Small molecules binding to histone proteins also control gene expression by chromatin remodelling Group of answer choices No answer text provided. True No answer text provided. false
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- Hyperacetylation of histone tails is often associated with: Question 22 options: Tight conformation of chromatin Loose conformation of chromatinWrite the word TRUE if the statement is correct and if false, replace the underlined words with the correct one. 1. Heterochromatin is typically gene-rich and composed of loosely-packed DNA that is transcriptionally active. 2. Molecular switches regulate the expression of genes by directing where and when genes should be turned on or off depending on the cell signal. 3. DNA Methylation and acetylation of histones are inverselycorrelated 4. Specialized cells produce specialized proteins derived from luxury genes which are constitutively expressed. 5. In mammals, methylation patterns that regulate DNA structure and gene expression become evident from the gastrula stage.The retinoblastoma tumor suppressor gene Rb (RB1) codes forthe retinoblastoma protein (pRB). pRB prevents the progression of the cell cycle through G1 if DNA has been damaged. Itdoes so in part because it binds a transcription-activatingdimer referred to as E2F-DP. The pRB-E2F/DP complex recruits a histone deacetylase to chromatin. Explain.
- "While other proteins come and go during the cell cycle, the proteins of the origin recognition complex remain bound to the DNA throughout" is true or false.Your favorite gene is expressed only in liver cells. Describe what this gene's chromatin looks like in brain cells and liver cells. Your answer re: Write your response here.. lat Reco zic GerThe activity of ________ will result in an increasedpositive charge on the histone. Question 24 options: Histone acetyltransferase Histone deacetylase Histone methyltransferase Maintenance methylase Histone demethylase
- Drag the term or statement to the correct column. Transcription factor stimulates own production Nucleosomes moved to new location Histone variants localized to specific locations Acetylation, phosphorylation, and methylation Cis Methylation on C Trans Molecular Mechanism Covalent addition to DNA Chromatin remodeling Covalent addition to histone Localization of histone variant Feedback loop Reset Change Cis or transEpigenetic changes in chromatin remodelling which selectively PREVENTS transcription Acetylation and phosphorylation of certain histone proteins Methylation Group of answer choices NEITHER 1 NOR 2 2 ONLY 1 AND 2 1 ONLYThe human phenotype is regulated by epigenetic control of gene expression. Discuss the three main types of epigenetic regulation, illustrating your answer with examples of diseases arising from impairment of each of these processes. 600 words.
- Which of the following statements most accurately represent chromatin state and transcription? Group of answer choices 1.Histone deacetylases promote closed chromatin and result in repressed transcription 2.Open chromatin is associated with hypoacetylation and has high levels of transcription 3.Histone acetyltransferases result in hypoacetylation and high levels of transcription 4.Hyperacetylation is associated with closed chromatin and low levels of transcriptionHeterochromatin and Euchromatin Have Which Different Histone modifications__________ is never involved in the initiation of eukaryotic transcription. Question 4 options: sigma factor trans-acting elements chromatin remodeling complexes cis-acting elements activators