Table 3: Toxic Doses and presentation of overdose symptoms. Acetaminoph en Aspirin Ibuprofen Naproxen Toxic Dose > 200 mg/ kg weight Estimated Toxic Dose for Mary The first symptoms occur a few hours after a toxic dose. These include: nausea, vomiting, excessive sweating, lack of appetite, and tiredness. Abdominal pain set in after 24-48 hours as liver damage occurs. In severe cases, after 3-5 days patients will experience yellowing of the skin, difficulty with blood sugar regulation, bleeding abnormalities, and liver swelling days. In severe cases, 1-2% of patients will die of liver failure in 4 to 18 days. > 300 mg/ kg Symptoms will occur within the first few hours after toxic dose. Symptoms could include irregular breathing, blurred vision, ringing in ears, seizures, diarrhea, rash, heartburn, and general confusion. >400 mg/kg Symptoms of an overdose generally occur within 4 hours of a toxic dose. Symptoms could include: heart burn and stomach pain, seizures and a lack of consciousness, changes in blood pressure and heart rate, and kidney failure. > 400 mg/kg weight Symptoms of an overdose generally occur within several hours of a toxic dose. Symptoms could include: heartburn, vomiting, seizures, lethargy, and a prolonged time for blood to clot.
Table 3: Toxic Doses and presentation of overdose symptoms. Acetaminoph en Aspirin Ibuprofen Naproxen Toxic Dose > 200 mg/ kg weight Estimated Toxic Dose for Mary The first symptoms occur a few hours after a toxic dose. These include: nausea, vomiting, excessive sweating, lack of appetite, and tiredness. Abdominal pain set in after 24-48 hours as liver damage occurs. In severe cases, after 3-5 days patients will experience yellowing of the skin, difficulty with blood sugar regulation, bleeding abnormalities, and liver swelling days. In severe cases, 1-2% of patients will die of liver failure in 4 to 18 days. > 300 mg/ kg Symptoms will occur within the first few hours after toxic dose. Symptoms could include irregular breathing, blurred vision, ringing in ears, seizures, diarrhea, rash, heartburn, and general confusion. >400 mg/kg Symptoms of an overdose generally occur within 4 hours of a toxic dose. Symptoms could include: heart burn and stomach pain, seizures and a lack of consciousness, changes in blood pressure and heart rate, and kidney failure. > 400 mg/kg weight Symptoms of an overdose generally occur within several hours of a toxic dose. Symptoms could include: heartburn, vomiting, seizures, lethargy, and a prolonged time for blood to clot.
Chapter17: Drugs And Medicine: Healing, Helping, And Hurting
Section: Chapter Questions
Problem 1SC
Related questions
Question
Based on a grade 11 chemistry student, answer the following question based on the provided information in the provided information:
Do you think Mary died due to an overdose of medication? Use evidence from your calculations to support your reasoning. Mary's weight is 50 kg.
Transcribed Image Text:Table 3: Toxic Doses and presentation of overdose symptoms.
Acetaminoph
en
Aspirin
Ibuprofen
Naproxen
Toxic Dose
> 200 mg/ kg weight
Estimated Toxic Dose for Mary
The first symptoms occur a few hours after a toxic dose. These include:
nausea, vomiting, excessive sweating, lack of appetite, and tiredness.
Abdominal pain set in after 24-48 hours as liver damage occurs. In
severe cases, after 3-5 days patients will experience yellowing of the
skin, difficulty with blood sugar regulation, bleeding abnormalities, and
liver swelling days. In severe cases, 1-2% of patients will die of liver
failure in 4 to 18 days.
> 300 mg/ kg
Symptoms will occur within the first few hours after toxic dose.
Symptoms could include irregular breathing, blurred vision, ringing in
ears, seizures, diarrhea, rash, heartburn, and general confusion.
>400 mg/kg
Symptoms of an overdose generally occur within 4 hours of a toxic
dose. Symptoms could include: heart burn and stomach pain, seizures
and a lack of consciousness, changes in blood pressure and heart
rate, and kidney failure.
> 400 mg/kg weight
Symptoms of an overdose generally occur within several hours of a
toxic dose. Symptoms could include: heartburn, vomiting, seizures,
lethargy, and a prolonged time for blood to clot.
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