The catalytic mechanism of bovine pancreatic RNase A relies upon acid-base catalysis involving the amino acid imidazole lysine histidine aspartic acid Oglutamic acid
Q: Use the table of the codons to answer the following question. Starting with the start codon, what is…
A: A codon is a sequence of three consecutive nucleotides in a DNA or RNA molecule that codes for a…
Q: A-DNA has a helix diameter of 25.5 Angstrom, a pitch per turn of 25.3 Angstrom, and a rise per base…
A: The A-DNA, B-DNA and Z-DNA are the commonly occurring structural conformations of DNA. The most…
Q: Cholesterol is An essential lipid molecule we can only obtain by ingestion O An essential lipid…
A: Cholesterol is a neutral lipid. It is a type of sterol. It is plays very important in the body by…
Q: For each fatty acid given, determine the following. Gross ATP from b-oxidation cycles Gross ATP…
A: Since you have posted a question with multiple subparts, we will solve the first three sub-parts for…
Q: The ATP yield from TCA cycle starting with two molecules of acetyl CoA is....... a) 15 ATP. b) 24…
A: Introduction: TCA cycle which is also known as the Kreb cycle is the last common oxidative pathway…
Q: Write a paragraph or more to introduce the enzyme catalase. Include the following details in your…
A: The enzyme catalase is found in nearly all living organisms that are exposed to oxygen. This enzyme…
Q: Which statement(s) regarding ions is true when a neuron is at rest? Positively charged cations are…
A: Neurons are also known by the name nerve cells. These cells are referred to as the fundamental units…
Q: For the binding of a ligand to a protein, what is the relationship between the Ka (association…
A: The ligand in protein-ligand binding is typically a molecule that generates a message by connecting…
Q: Question #8 Shown below are the chemical structures of several cofactors that are used in enzyme…
A: The names and properties of the coenzymes are as follows:
Q: electrochemical potential is a compounds solubility in oil versus water and determines how easily it…
A: The fluid mosaic model describes the cell membrane as a mosaic of several types of molecules like…
Q: Select the molecules that contains sphingosine. Molecule C phosphatidylcholine Molecule B Molecule A…
A: Phospholipids are compound lipids composed of fatty acids, alcohol, and a phosphate group.…
Q: Draw the structure of 1-palmitoleyl-2-linolenyl-3-stearyl triacylglyceride
A: A triacylglyceride contains a glycerol molecule (has 3 carbon backbone) & to each carbon a fatty…
Q: Label what these 2 reactions represent
A: Many biochemical reactions involved more than one substrates in which enzyme catalyzed the…
Q: Every amino acid that undergoes catabolic breakdown give rise to an ammonia molecule that must be…
A: There are 20 naturally occurring amino acids that are found in proteins. Amino acids can be…
Q: What the most important difference between cellulose and other polysaccharides discussed in class…
A: Cellulose is a type of carbohydrate that is mostly present in the plants. It is generally not…
Q: Use the Michaelis-Menten plot to answer this question. What is the estimated value of Vmax of the…
A: Vmax : Reaction rate- when the enzyme gets fully occupied by substrate. Vmax- Maximum velocity
Q: Why are nucleic acids considered a non-essential component of the diet? Bases, specifically purines…
A: Nucleic acids are biomolecules composed of nucleotide units. Each nucleotide unit is composed of a…
Q: What is the role of tyrosine in prostaglandin synthesis? Tyrosine provides the proton to the double…
A: Prostaglandins are mostly produced from Arachidonic acids( a C20 poly-unsaturated fatty acids) in…
Q: METHOD : Touch different surfaces after that sanitize your hand with 40% alcohol then touch the…
A: Introduction: Disinfectants are substances that are applied to non-living objects in order to…
Q: pH and cells, hypothesis In the Functions of Buffers simulation, a good hypothesis would be:…
A: Introduction: The cytoplasm is the inside environment of a cell that is surrounded by a membrane. It…
Q: student performs a separation by TLC on a silica get plate that results in three spots. A red spot…
A: Introduction: Thin-layer chromatography (TLC) is an important technique for the identification and…
Q: Which syndrome is most closely associated with gluten sensitivity?
A: Gluten is a protein that can be found in a variety of grains, including wheat, rye, spelt, and…
Q: Below is a nucleotide base pair from B-DNA with three different regions indicated by A, B, and C. C…
A: If we represent the nitrogen base as a triangle, there are going to be three edges: Hoogstein Edge:…
Q: Which of the following is not a potential biological role of the lipid asymmetry of the plasma…
A: The plasma membrane is also known by the name cell membrane. This membrane is found in all the major…
Q: A feature of obesity that causes it to impact on many diseases is low level inflammation and the…
A: Obesity is a complex disease and occurs due to accumulation of excessive amount of body fat. Obesity…
Q: Given 60 glucose molecules available in a muscle fiber to undergo aerobic respiration, how many H+…
A: ETC is coupled with ATP synthesis. ETC occurs in Cristea (inner mitochondrial membrane). ETC…
Q: 7. cis 20:5(45,8,11,14,17) 20:5;5,8,11,14,17 w3,6,9,12,15 8. trans 20:5(45,8,11,14,17)…
A: Cis and trans Fatty differ in the arrangement of hydrogen atoms on the double bonded Carbon atom.…
Q: You wish to perform an electrophoretic resolution of your restriction enzyme–digested DNA. The sizes…
A: Agarose gel electrophoresis is a method of gel electrophoresis that is used to separate a mixed…
Q: Which enzyme catalyzes the conversion of Cholesteryl ester to cholesterol and fatty acid?…
A: Cholesteryl ester is a dietary lipid that is an ester of cholesterol. The carboxylate group of fatty…
Q: The following strand of DNA is transcribed: 5'-GACCTCCGAATGC-3' Write the sequence of the…
A: Transcription- formation of mRNA from DNA In , RNA A pairs with U G pairs with C
Q: In vision, vitamin A serves as a cofactor for key enzymatic reactions needed for vision is…
A: Rods (in the periphery) and cones (in the center) make up the eye's retina. Cones are essential for…
Q: In the α helix the hydrogen bonds: a. are roughly parallel to the axis of the helix. b. are roughly…
A: α-helix is the secondary structure of proteins which is a common motif found in proteins. Hydrogen…
Q: Modify the amino acid by adding or removing atoms or bonds and by adding charges where appropriate.…
A: Note : Hi ! Thank you for the question. We are authorized to answer one question at a time. Since…
Q: 1. ATP ACCOUNTING Provide what is being asked for. Show all relevant calculations and summarize your…
A: Complete Oxidation of odd numbered fatty acids like 17:0 fatty acid (given in the question) requires…
Q: You obtain the following results for the transport of an amino acid into bacteria. Based on this…
A: The cell membrane presents a hydrophobic barrier that separate the interior of the cell from the…
Q: How would IgG enhance innate immune system
A: Introduction: Immune system is a defense mechanism of body which protects us from any foreign body…
Q: The three-dimensional conformation of a protein may be strongly influenced by amino acid residues…
A: Proteins are unbranched polymers constructed from 20 standard α-amino acids. They have four levels…
Q: It's a three part question based on the chart provided asking: a) Which of these enzymes has the…
A: For an enzyme catalyzed reaction, Km is the substrate concentration that is required to attain half…
Q: 1. What are the clinical manifestations of hyperglycemia? 2. What are the clinical manifestations of…
A: Hyperglycemia is a condition wherein a person has high levels of blood sugar, resulting from…
Q: Ferritin is a blood plasma iron transport protein O True O False
A: Iron (Fe) is very important in our body as it acts as cofactor. When iron enters the cells of our…
Q: What is the primary reason the a-helix conformation in polypeptides such a stable form? A. The…
A: The secondary structure of protein determines the local spatial arrangement of the amino acids in…
Q: ALL biosynthetic reactions require which of the following metabolites(s)? NADPH Glucose 6-P High…
A: Biosynthetic reactions are the reactions that are catalysed by Enzymes to synthesise more complex…
Q: What are the most important roles of starch in the cooking? Explain
A: Introduction: Starch is a carbohydrate that contains a large number of glucose units that are…
Q: CI The common name for metabolite 4 How does its structure differ from diazepam? HO НО Metabolite 4…
A: The distinctive chemical structure of molecules that are used as drugs gives them their…
Q: explain the chemical reaction that occurs water molecules dissociate and reform. why is these…
A: Water is an essential molecule of life. Water is made up of two atoms of hydrogen along with one…
Q: Reducing power for the synthesis of fatty acids is produced in which reactions? conversion of…
A: The fatty acid synthesis starts from acetyl Co-A which is an intermediate of the TCA cycle. The…
Q: 1. ATP ACCOUNTING, Provide what is being asked for. Show all relevant calculations and summarize…
A: Almost all fatty acids (are carboxylic acids) are hydrocarbon components of lipids, these chains…
Q: 3. A 45-year-old woman was admitted to hospital because of frequent headaches, muscle weakness,…
A: Adrenal glands are the glands located above the kidneys. The adrenal glands have two regions known…
Q: Which of the following mechanisms ensure that the utilization of dietary nucleic acids is effected?…
A: Purine and pyrimidine biosynthesis occurs from the waste products of other metabolic pathways like…
Q: A3 Glucosylacetamide has a structure similar to the transition state during catalysis by the enzyme…
A: The chemical compounds that have structure similar to that of transition state substrate are called…
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
- Using the catalytic mechanism of serine proteases, draw and label a reaction coordinate diagram/graph of the chymotrypsin-catalyzed hydrolysis of a peptide bond.When hyaluronan synthase from Pasteurella multocida was expressed in E. coli, the bacteria spun out a capsule of hyaluronan. This reaction was analyzed using purified membrane fragments containing the hyaluronan synthase, a radio-labeled tetrasaccharide acceptor (Part A), along with the activated forms of the sugar subunits: UDP-N-acetylglucosamine and UDP-glucuronic acid. In short incubations with the complete mixture, the tetrasaccharide primer elongated by several units, although only odd-numbered chains were visible (Part B lane 2). If one or both activated sugars were left out, the results shown in lanes 3-5 (Part B) were obtained. Why do you suppose that only odd-number chains are visible in your assay? (A) ACCEPTOR nonreducing end HO- HO OH COO glucuronic acid (GICUA) HO- CH3 T C=O I NH CH₂ OH N-acetylglucosamine (GlcNAc) COO но- HO OH OH I CH₂ reducing end NH C=O CH3 Choose one: O A. Synthase adds GlcNAc much more slowly than it adds GICUA. O B. One of the monosaccharide…Amino transferases catalyze the transfer of amino groups to alpha-keto acids with pyridoxal phosphate as the prosthetic group. Pyridoxal phosphate can accept an amino group, and its aminated form, pyridoxamine phosphate, can donate its amino group to an alpha-keto acid. Draw the detailed mechanism of the transamination reaction in the active site of an aminotransferase. Use the glutamate oxaloacetate transaminase as an example.
- In the serine protease triad, the proximity of an aspartatecarboxylate group to the imidazole group of histidine raisesthe latter’s pKa. Explain.Briefly describe the induced-fit conformational change when hexokinase binds its substrate.. (a) Explain the biochemical basis for the fact that one can synchro- nize cell populations by treating them with deoxythymidine. (b) Explain the apparent paradox that DATP at low concentrations is an activator of ribonucleotide reductase, whereas at higher concen- trations it becomes inhibitory.
- . (a) Explain the biochemical basis for the fact that one can synchro- nize cell populations þy treating them with deoxythymidine. (b) Explain the apparent paradox that dATP at low concentrations is an activator of ribonucleotide reductase, whereas at higher concen- trations it becomes inhibitory.Why Phenylmethylsulfonyl fluoride (PMSF, shown in Fig.) does not inhibit aspartate protease as potent as serine protease?Lysine degradation requires removal of two amino groups. Removal of itsε-amino group gives a-aminoadipic semialdehyde. This product is thendegraded to acetoacetate by the same chemical strategy used to degrade thebranched-chain amino acids. Draw the proposed intermediates in this pathway (Hint: see Figure 18.14).
- The mitochondrial form of carbamoyl phosphate synthetase is allosterically activated by N-acetylglutamate. Briefly describe a rationale for this effect.Serine Proteases, such as chymotrypsin, contain Ser/Asp/His as a catalytic triad (i.e. three collaborating amino acids) of amino acids involved in enzyme catalysis. Why is this? Examine each amino acid of this catalytic triad (schematically detailed below: Ser195/Asp102/His57) and, based on your understanding of amino acid characteristics, predict what the role of each amino acid could be. His57 Ser195 Asp102What would be the effect on the activity of phosphofructokinase of the mutation of Asp103 to the unusual amino acid shown below? Explain in terms of actual structures of the side chains of Asp and this unusual amino acid.