The initial plasma concentration of a drug given iv at 8:00am is 210 mg/ml. If the half life of the drug is 6 hours, what will the plasma concentration be at 7:00pm that same day?
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The initial plasma concentration of a drug given iv at 8:00am is 210 mg/ml. If the half life of the drug is 6 hours, what will the plasma concentration be at 7:00pm that same day?
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- The peak plasma concentration achieved after the first IV dose of drug X is 25 mg/L. The drug’s half-life is 3.5 hours, and it is administered every 12 hours. What will be the peak plasma concentration at steady state?Mrs B presents you with a prescription for warfarin tablets 1 mg. The directions are to take 6 mg at 6pm that evening, followed by alternating daily doses of 4 mg and then 3 mg (as long as her INR remains within the recommended range). What is the exact number of warfarin 1 mg tablets required for a 28 day supply assuming her INR remains in range?The nurse is preparing to give Acetaminophen to a 5year old girl weighing 20 kg. The doctor has ordered Acetaminophen 240mg PO qehr PRN pain. the safe dose range for acetaminophen is 10-15 MG/KG/dose. What is the low safe amount per dose? [1] What is the high safe amount per dose? (2) is this dose safe to give? (3]
- 100 mg dose of Drug X is administered via IV at 7 hours, blood drug concentration is 5 mcg/mL Half-life of the Drug X is 5 hours A. Find the blood concentration after 6 hours if the dose is 1g (should be between 50.39 and 61.6) B. Minimum effective concentration is 2 mcg/mL. IF the first dose was 100mg of Drug X, how many hours after the dose would reach to 2mcg/mL. (When should the 2nd dose be given). (should be between 12.06 and 14.74)The medication order for a patient is 150 mL of drug A over 2.0 hours with a drop factor of 12 gtt/mL. What is the flow rate in drops/min?A 160lb patient disagnosed with supraventricular tachycardia is to receive verapamil 5mg IV over 2 minutes. The drug is available in 4mL vials containing 2.5mg/mL. How many mL will you administer?
- n 10-kg infant requires a continuous infusion of a drug to run at 1 mL/hr to deliver 3 mcg of drug/kg/min. Calculate the milligrams of drug that must be added to a 100-mL IV infusion solution.The order is for 0.35 mg of epinephrine stat; the drug is available as an ampule with the concentration labeled as 1:1000 (weight in grams: volume in mL). How much volume should be administered to the patient per dose? 1) 0.035 mL 2) 0.35 mL 3) 3.5 mL 4) 35 mLA prescription order calls for 1.25 g of vancomycin in 500 mL of NS (0.9%/100mL). After reconstitution vancomycin injection is available in a strength of 50 mg/mL. How many mL of vancomycin injection should be drawn up to prepare this prescription?
- A patient, whose weight is 80.5 kg and height is 63 inches, is to receive dacarbazine in 250 mL 5% dextrose injection over 30 to 60 minutes. Dacarbazine is available as 200 mg/vial reconstituted to 10 mg/mL. How many mL will be needed to add to the IV bag?The client was ordered Oral Phenergan 0.1g, TDS (three times a day). The pharmacy has dispensed Phenergan 25mg tablets. How many tablets will you administer? What dose of Phenergan will this client receive in 24 hours?From an economic point of view, the consultancy firm wanted to calculate the price a patient would need to pay for the full treatment. The cost of each vial of the drug ‘A’ is $450.50 dollar where it contains 30 mg. The usual dose of drug administered is 145 mg once every 2 weeks, during a 12-week period to a patient weighing 190 lb and a height of 6 ft 2 inch. Calculate the cost for the full treatment for the above patient.