Q: How can a defect in p53 gene contribute to cancer development?
A: Cancer is an abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some…
Q: What is the link between epigenetics and cancer?
A: Epigenetics is considered as the study in which the gene shows its behavior according to the…
Q: How can the role of epigenetics in cancer be reconciled with the idea that cancer is caused by the…
A: Epigenetics is the study of various alterations in an organism occurred because of certain gene…
Q: Should genetic testing for cancer be availablefor everyone, or should genetic testingbe confined to…
A: Cancer is an abnormal proliferation of body cells that has undergone mutation. The cancer is of…
Q: What would make someone think they might have developed cancer and seek medical testing?
A: Cancer is a medical condition in which cells become abnormal and divide uncontrollably which leads…
Q: What are Two kinds of cancer-producing mutations?
A: Cancer is defined as any one of a large number of diseases characterized by the development of…
Q: Why is this system promising in curing cancer and genetic diseases? What are some of the…
A: Introduction Gene therapy involves changing the genetic instructions within a person's cells to…
Q: How can researchers pinpoint the particular driver mutations most responsible for the cancer…
A: The development of cancer is an evolutionary process at the cellular level. Several mutations…
Q: Why are people more likely to develop cancer as they age? Why does inheriting a mutation increase…
A: Cancer is the name given to a collection of related diseases.In all types of cancer,some of the…
Q: If cancer is fundamentally a genetic disease, how might an environmental factor such as smoking…
A: Tumor is a mass of tissues. It may be benign or malignant. The cellular growth that occurs when the…
Q: What is the cancer stem cell hypothesis?
A: Every living organism is made up of cells. A cell is a small self-contained unit within a whole…
Q: Why do mutations in DNA repair genes increase the likelihood of developing cancer?
A: Deoxyribonucleic acid (DNA) is a hereditary molecule that transfers genetic information from one…
Q: How can cancer arise from stem cells?
A: Stem cells are unique human cells and can grow into several cell types. This can vary between cells…
Q: What is the relationship between genetic mutations and cancer?
A: Mutation is defined as change in nucleotides nitrogenous base.
Q: What genes are involved in cancer?
A: Genes Involved In Cancer --- Genes and Their Characteristics -- Genes are made up of pieces of DNA…
Q: What are the requirements for normal cell division? What are the requirements for cancer cells…
A: Mutation is defined as an erroneous change within the gene sequence of an organism that leads to a…
Q: How is DNA methylation related to cancer?
A: The alteration to the structure of chromatin affects the gene expression, which is known as…
Q: How do normal cells protect themselves from accumulating mutations in genes that could lead to…
A: Studies reveal that the p53 protein instructs cells to under-go apoptosis when mutations in the DNA…
Q: How do oncogenes differ from tumor suppressor genes?
A: Oncogenes are a physically and functionally diverse set of genes, the protein products of which act…
Q: Cancer can arise spontaneously, but it can also be induced as a result of environmental factors such…
A: Cancer is a collection of diseases characterized by abnormal and uncontrolled growth. Cancer arises…
Q: How Mutations Cause Cancer Phenotypes?
A: The medical condition of cancer is generally characterized by the presence of a cluster of cells…
Q: relationship that may exist between mutations and cancer
A: Any permanent change occurring in the DNA base sequence is referred to as a mutation. The mutation…
Q: Many of the mutations in cancer samples are not necessarily driver mutations, but rather passenger…
A: Hematologic childhood cancer can develop in any part of the body, including the blood and lymph…
Q: How do we know that many cancer-causing agents (carcinogens)are also mutagenic?
A: A large number of chemicals and several physical agents, such as UV light and γ-radiation, have been…
Q: How do stem cells retain this capacity, and can we harness it to cure debilitating diseases?
A: Stem cells: Stem cells are the cells that have the potential to develop into different types in the…
Q: How oncogenes contribute to cancer?
A: Cancer: It is a disease where cells divide abnormally and damage other cells. There are…
Q: Let’s suppose you were interested in developing drugs to preventepigenetic changes that may…
A: Genes are basic physical and functional unit of heredity. It is a part of DNA that has instruction…
Q: What separates cancer cells from normal cells?
A:
Q: What technique is used to identify genes involved in cancer formation ?
A:
Q: What type of epigenetic changes are associated with cancer?
A: Epigenetic changes or modifications are important for maintenance of tissue specific gene…
Q: How tumor-suppressor mutations contribute to cancer?
A: Cancer - Cancer is a type of disease in which cells divide in an uncontrolled manner. The cells…
Q: What types of evidence indicate that cancer arises from genetic changes?
A: Cancer is a disorder in which abnormal cells divide irrepressibly and destroy the tissues of the…
Q: Sequencing the human genome, the development of microarray technology, and personal genomics promise…
A: To describe: How are Sequencing the human genome, the development of microarray technology, and…
Q: How does the normal p53 protein inhibit cancer development?
A: Tumor-suppressor genes code for proteins that repair damaged DNA (preventing a cell from turning…
Q: Mutations that increase the creation of blood vessels and turn on expression of telomerase are....…
A: Reactivation of telomerase could be valuable in certain types of cell treatment and doesn't seem…
Q: What could cause cancer in our natural environment? Or what activities do we carry out that could…
A: Cancer: Cancer is the condition of uncontrolled growth of abnormal cells anywhere in a body. These…
Q: What is a tumor suppressor? What is an oncogene?
A: Cancer is a diseased condition where the cells show abnormal growth and proliferation. The cancerous…
Q: How to do a cancer data dictionary?
A: The cancer data dictionary is a cluster of information about a cancer diagnosis. The data is…
Q: How do radiation and chemical mutagens cause DNA damage?
A: Mutagen It is the factor that cause irreversible and heritable change in the genetic material means…
Q: Discuss the concept of cancer survivorship ?
A: Survivorship in cancer refers to the health and well-being of a cancer patient from the time of…
Q: What are the two principal opposing views regarding the patenting of genes?
A: Gene patent is a patent on a specific isolated gene sequence, a natural sequence that has been…
Q: Which of the following is an enabling characteristic for cancer that can increase the likelihood of…
A: The somatic mutations in the genome of a cancer cell, irrespective of their structural nature, can…
Q: How can mutations in noncoding segments of DNA contribute to the development of cancers?
A: The functions segment of hereditary material that mainly codes for the proteins is a gene. The…
Q: What is the role of regulatory gene mutations in cancer?
A: Regulatory genes are defined as genes which control or regulate the expression of one or multiple…
Q: how can mutations in several genes drive cancer?
A: Ans: Mutation: The change in the nucleotide sequence base level (single base) is referred to as…
Q: what are the rolls that the p53 gene and RAS protein take on when trying to stop a cancer cell from…
A: Given: Role of p53 and RAS protein to stop a cancer cell from replication. What happens if mutation…
What are the biggest challenges that mutations pose to oncologists and cancer biologists who seek to find novel cures against cancers?
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- What are the ethical issues associated with gene and cell therapy? What are stem cells? Why are stem cells so important in gene and cell therapy?What is the cancer stem cell hypothesis?Which of the following is an enabling characteristic for cancer that can increase the likelihood of both passenger and driver mutations? a) Increased angiogenesis O b) Tumor-promoting inflammation O c) Avoiding immune destruction O d) Genome instability acer
- name any two methods that can possibly cure cancer .b) What is one reason that it is challenging to treat cancer?1) What are the limitations of targeted versus whole-genome or whole-exome profiling of cancer mutations? 2) What can you infer about mutations that are common to almost all of the cells in a tumor? 3) Summarize the high-level differences between the VCF and MAF file formats. 4) How do germline and somatic mutations differ in terms of their effect on cancer risk and prognosis?
- Why has gene therapy not been the success that was expected when it was first proposed as a viable means of treating genetic disorders?Why are bone marrow stem cells ideally suited as targets for gene therapy?Which of the following effectively describes the situation of someone with an inherited predisposition to cancer such as familial adenomatous polyposis or BRCA-associated familial breast cancer? Choose all that apply a) If they get malignant cancer, somatic mutations will not have been a factor b) Their cancer will most likely arise in their germ cells, not their somatic cells c) None of the answers effectively describes the situation d) Every cell of their body contains a gain-of-function allele of an oncogene e) Most cells in their body contain multiple cancer-causing mutations f) Every cell of their body contains a defective, loss-of-function allele of a tumor suppressor gene
- What separates cancer cells from normal cells? Describe one form of mutation that can increase the risk of a normal cell being cancerous.Why is it important to model cancer through the generation of induced pluripotent stem cells ? Please list item by item. Explain in detail the main findings.Although it is well known that X-rays cause mutations, they are routinely used to diagnose medical problems, including potential tumors, broken bones, and dental cavities. Why is this done? What precautions need to be taken?