What is the function of the kinase associated with the pyruvate dehydrogenase complex?
Q: Briefly describe the dual role of lipoic acid in the pyruvate dehydrogenase complex
A: Lipoic acid is essentially used in aerobic processes. It is important biological compound for the…
Q: can you explain the catalytic mechanism of pyruvate dehydrogenase (complex)
A: Pyruvate dehydrogenase is a multimeric protein involved in the glycolytic pathway of the cell which…
Q: How does the action of allosteric effectors differ in the reactions catalyzed by phosphofructokinase…
A: Glycolysis is breakdown of glucose. It is a ten step enzymatic process. Phosphofructokinase is an…
Q: How does control of the glucose6-phosphatase reaction differ from that of the fructose-1,6-…
A: Gluconeogenesis is the formation of glucose. It resembles reversal of glycolysis. Three steps of…
Q: What is alpha keto glutarate dehydrogenase complex?. explain very briefly.
A: Tri carboxylic acid (TCA) cycle is an amphibolic pathway that means it involves both catabolic and…
Q: How many acetyl CoA molecules can be produced during the complete β-oxidation of this fatty acid?
A: Answer- Beta oxidation is the biochemical reaction in which fatty acids molecules are broken down to…
Q: Which isoenzyme of Lactate dehydrogenase is present in blood?.
A: Isoenzymes are physically different from of enzyme that catalyses same biochemical reactions.
Q: Which of the enzymes in glycolysis are NADH linked dehydrogenases?
A: Glycolysis is the first step in energy production from glucose. Carbohydrates from the food are…
Q: What are the steps involved (in order) in the conversion of pyruvate to acetyl CoA?
A: Conversion of pyruvate to acetyl CoA: Pyruvate is the end product of glycolysis and acetyl CoA is…
Q: Why is reciprocal regulation a key feature of glucose metabolism?
A: Carbohydrate metabolism is the whole of biochemical processes responsible for the metabolic…
Q: Why does it make metabolic sense for ADP and GDP to inhibit ribose phosphate pyrophosphokinase?
A: Ribose phosphate phosphokinase or ribose-phosphate pyrophosphokinase (RPPK) is a phosphoribosyl…
Q: The action of glucagon on liver cells leads to inhibition of pyruvate kinase. What is the most…
A: Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It works to raise the…
Q: Which one of the five steps of the pyruvate dehydrogenase complex reaction is most likely to be…
A: Pyruvate dehydrogenase complex is a group of non-covalently associated enzymes. It catalyzes…
Q: The serine residues in acetyl CoA carboxylase that are the target of the AMP-activated protein…
A: Fatty acids are carboxylic acids that contain a long aliphatic chain that could be either branched…
Q: How does an increase in the NADH/NAD+ratio affect the activity of pyruvate dehydrogenase?
A: The enzyme pyruvate (PDH) dehydrogenase is the major protein complex that helps to connect…
Q: How does the action of allosteric effectors differ in the reactions catalyzed by phosphofructokinase…
A: Allosteric effectors are the molecules that bind with one of the active sites of an enzyme that are…
Q: Which of the following does not correctly describe the isozymes of lactate dehydrogenase (LDH) in…
A: Lactate dehydrogenase (LDH) is an enzyme which catalyzes the conversion of lactate to pyruvate along…
Q: The glycerol derived from lipolysis of triacylglycerols is converted into glyceraldehyde…
A: Glycolysis is considered as a process in which glucose is converted into pyruvate molecule.
Q: How do aminotransferases and glutamate dehydrogenase cooperate in the metabolism of the amino group…
A: Aminotransferases belong to transferases enzyme that transfers one group into another and glutamate…
Q: How does an increase in the NADH/NAD1 ratio affect the activity of pyruvate dehydrogenase?
A: Introduction: The citric acid cycle is a series of reactions that yield two carbon dioxide…
Q: What are the current treatments for Pyruvate Kinase Deficiency (PKD) patients?
A: Pyruvate kinase deficiency is a genetic disorder in which the enzyme pyruvate kinase, which is…
Q: Which complex contains Succinate dehydrogenase and what are the roles of thisenzyme?
A: Succinate dehydrogenase is a part of the cellular biochemical machinery for breaking down sugars,…
Q: What is the fate of cytosolic pyruvate when it is reduced by cytosolic NADH?
A: The metabolic pathway is be defined as the series of chemical reactions occurring in a living…
Q: What is the function of NAD+ in the pyruvate dehydrogenase complex?
A: Pyruvate is formed from glycolysis. This pyruvate gets converted to acetyl CoA by oxidative…
Q: What are the effects of Glucose-6 Phosphate Dehydrogenase Deficiency? Explain its mechanism of…
A: Glucose 6 phosphate dehydrogenase is an important Enzyme of redox metabolism in RBC in which it…
Q: How is Pyruvate Kinase Deficiency (PKD) inherited? What gene is responsible for the expression of…
A: Pyruvate kinase is an enzyme that regulates cell metabolism by catalysing the conversion of…
Q: If acetyl-CoA is labeled with 14C at its methyl group, how many rounds of the cycle are required…
A: Acetyl CoA is an organic molecule further transformed into oxaloacetate that joins the citric acid…
Q: Why is pyruvate referred to as the hub of glucose oxidation?
A: Glycolysis is the oxidation of glucose to produce carbon dioxide and water. Pyruvate is the…
Q: Which amino acids can be converted to pyruvate by a single enzyme-catalyzed reaction?
A: Pyruvate is a three-carbon compound that is the end product of the glycolysis pathway. Pyruvate is…
Q: When one of the acetyl CoA is processed through the citric acid cycle, how many times does a…
A: In the Krebs cycle, the acetyl CoA is undergone into the cyclic process and result in the formation…
Q: What is the common end-product of the catabolism of the branched chain amino acids that are…
A: Amino acids are converted to the TCA cycle intermediates through transamination reactions. The TCA…
Q: What type of reaction is catalyzed by isocitrate dehydrogenase and a-ketoglutarate dehydrogenase?
A: Oxidative decarboxylation is a process in which carbon dioxide is produced through the removal of a…
Q: Is AMP an allosteric inhibitor or activator of glycogen phosphorylase in the muscle or liver
A: Muscle glycogen phosphorylase: AMP act as activator of glycogen phosphorylase -a form (active form)…
Q: What is the advantage for some tumors to stop expressing the genes for glucose-6-phosphatase,…
A: Glucose-6-phosphate, phosphoenolpyruvate carboxykinase, and fructose bisphosphatase are the three…
Q: How does pyruvate from glycolysis get to the pyruvate dehydrogenase complex?
A: Pyruvate dehydrogenase complex : It is a complex of three enzymes that converts pyruvate into…
Q: What is the advantage of activating pyruvate kinase with fructose-1,6-bisphosphate?
A: Glycolysis is the metabolic pathway that converts glucose into pyruvate and hydrogen ion through…
Q: What coenzymes are required by the pyruvate dehydrogenase complex? What are their roles?
A: A coenzyme is a non-protein component of an enzyme that is required for the enzymatic reaction to…
Q: Which citric acid cycle intermediate can be converted to an amino acid in one transaminase step?
A: "Hi! As you have posted multiple questions and have not mentioned which is to be answered, we are…
Q: How does an increase in the ADP/ATP ratioaffect the activity of isocitrate dehydrogenase?
A: Isocitrate dehydrogenase and is an enzyme that catalyses the oxidative decarboxylation of…
Q: What prevents the phosphatase activity of PP1 from always inhibiting glycogen degradation?
A: Introduction: Glycogen is stored in the liver and skeletal muscle. To maintain the glucose levels in…
Q: What is the first cofactor to accept electrons from pyruvate in the Pyruvate dehydrogenase complex?
A: Pyruvate dehydrogenase enzyme is a multi enzyme complex which links glycolysis to krebs cycle.…
Q: describe how the pyruvate dehydrogenase complex is regulated?
A: Pyruvate dehydrogenase complex (PDC) is a three-enzyme complex that decarboxylates pyruvate into…
Q: explain the difference between pyruvate carrier and pyruvate dehydrogenase complex?
A: Pyruvate refers to the conjugate base of pyruvic acid is an important intermediate in many metabolic…
Q: How does compromised pyruvate kinase activity lead to anemia?
A: Pyruvate kinase is a catalytic enzyme that catalyzes the final step of glycolysis, which is crucial…
Q: what linkage does glycogen synthase catalyzes?
A: Glycogen synthase is an enzyme involved in glycogen synthesis. Glycogen is synthesized from extra…
What is the function of the kinase associated with the pyruvate dehydrogenase complex?
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- Identify the means by which the pyruvate dehydrogenase complex is regulated.What is the advantage for some tumors to stop expressing the genes for glucose-6-phosphatase, phosphoenolpyruvate carboxykinase, and fructose bisphosphatase?One treatment for shock is to administer dichloroacetate (DCA), which inhibits the kinase associated with the pyruvate dehydrogenase complex. What is the biochemical rationale for this treatment?