What occurs in the liver of an alcoholic drinker? * O Activity of TCA cycle is reduced due to oxaloacetate deficiency. More and more dihydroxy-acetone phosphate is produced. ONADH depletion due to ethanol oxidation by alcohol dehydrogenas All choices are correct.
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- Which enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferaseLactate dehydrogenase O is needed for oxidative metabolism of glucose O only functions in muscle O only operates early in exercise O Is used to both produce and consume lactate. Glucagon secretion causes inhibition of intracellular acetyl-CoA car- boxylase activity by several mechanisms. Name all you can think of.
- Alpha-ketoglutarate dehydrogenase exhibits feedback inhibition byvny can acetone sometimes be detected in the breath of patients with type 1 diabetes? A. Glucagon signaling is faulty, leading to an excess of oxaloacetate, which enables acetyl-CoA to enter the citric acid cycle, therefore resulting in the production of ketone bodies including acetone OB. Insulin signaling is faulty, so excess malonyl-CoA is generated, which leads to excess acetyl-CoA from beta oxidation Oc. None of the other answers is correct OD. Insulin signaling is correct, but excess acetyl-CoA is generated anyway, leading to the production of ketone bodies including acetone O E. Insulin signaling is faulty, fatty acids are catabolized to acetyl- COA despite high blood glucose, and excess acetyl-CoA is converted to ketone bodies,What is the function of glyceraldehyde 3-phosphate dehydrogenase? catalyzes the transfer of a phosphoryl group from ATP to an acceptor oxidation of the alcohol to an aldehyde dehydration and dephosphorylation of GAP hydrolysis of GAP oxidation by NAD+ and formation of acyl-phosphate
- Loss of muscle tone is associated with which deficiency? O All deficiencies mentioned O None of the given O Alpha-ketoglutarate deficiency Succinate dehydrogenase deficiencyOf the allosteric enzymes listed below, which are suppressed by NADH? Select all that apply. the pyruvate dehydrogenase complex a-ketoglutarate dehydrogenase complex U isocitrate dehydrogenase pyruvate kinase Ophosphofructokinase hexokinase OglucokinaseA. What would happen in the Krebs cycle with the loss of activity of phosphoglycerate kinase? What would happen in glycolysis? 10. What happens to glycolysis with the addition of high amounts of citrate? What happens to ETS? 11. What happens in the Krebs cycle with a block in fumerase? 12.If an amino acid enters the Krebs cycle at the acetyl CoA entry point, how much more ATP is being made than if it enters at a keto-glutarate?
- Which of the following reactions required dihydrolipoyl dehydrogenase? Oxidative decarboxylation of pyruvate Oxidative decarboxylation of a-ketoglutarate Both A and B Neither A nor B Fatty acid biosynthesis is stimulated by: Decreased levels of citrate Increased levels of palmitoyl-CoA Increased levels epinephrine Increased levels of AMP All of the above None of the above. Identify the Krebs cycle enzyme which acts on a five-carbon substrate, produces a four-carbon product substituent (attached to coenzyme A), and generates one molecule of NADH. a-ketoglutarate dehydrogenase pyruvate dehydrogenase citrate synthase malate dehydrogenase succinate dehydrogenase Which of the following enzymes consumes one molecule of NADH, during anaerobic fermentation in yeast, as it converts a two-carbon substrate molecule into a two-carbon product molecule? succinate dehydrogenase pyruvate decarboxylase C. isocitrate dehydrogenase lactate dehydrogenase alcohol dehydrogenaseConsider the following reaction sequence. glucose 1-phosphate + UTP UDP-glucose +-0-P-0- UDP-glucose + (glucose), UDP + (glucose),+1 Which of the following characterizes this process? consumes energy O all of these anabolic O a step in gluconeogenesis