When 0.066g of cholesterol is dissolved in 1.00 mL of ether and placed in a sample cell 10.0 cm in length, the observed rotation 20°C (using the D line of sodium) is -0.208°Calculate the specific rotation of cholesterol. specific rotation [a] = i

When 0.066g of cholesterol is dissolved in 1.00 mL of ether and placed in a sample cell 10.0 cm in length, the observed rotation 20°C (using the D line of sodium) is -0.208°Calculate the specific rotation of cholesterol. specific rotation [a] = i

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter3: Stereoisomerism And Chirality

Section3.7: Optical Activity—how Chirality Is Detected In The Laboratory

Problem 3.9P

See similar textbooks

Related questions

Q: The specific rotation of (-) isomer is -22˚, with concentration of 4.2 g/100 mL, and pathlength of…

A: Specific rotation, [α]: It is the rotation caused by a sample at a concentration of 1.0 g/mL in a…

Q: The specific rotation of a pure substance is -5.90°. What is the percentage of this isomer in a…

A: The optical purity is calculated by the formula, Optical purity=observed specific rotationspecific…

Q: the specific rotation of sucrose is 66.5(°cm^3)/(gdm), what is its molar rotation? Molar mass of…

Q: 7. A 0.5 gram sample of hoodia gordonii isolated from natural sources yields an observed rotation of…

A: (a)Determine the specific rotation [α] of hoodia gordonii for the given entities:

Q: When 0.247 g of monosodium glutamate (MSG) is dissolved in 10.0 mL of water and placed in a sample…

A: We are authorized to answer one question at a time, since you have not mentioned which question you…

Q: 13. When 0.095 g of cholesterol is dissolved in 1.00 mL of ether and placed in a sample cell 10.0 cm…

A: Specific rotation of a sample is calculated by the formula given as follows: Specific…

Q: A 1.26 M solution of (R)-2-butanol is mixed with an equal volume of a 0.630 M solution of racemic…

A: The angle of rotation of a plane polarized light by the optically active compound is known as…

Q: 1) The specific rotation of (R) -2-bromooctane is -36 . What is the percentage composition of a…

A: Given: Specific rotation of pure enantiomer (R)-2-bromooctane = -36 o And the mixture rotation = +12…

Q: A pure B-D-hexose solution has an initial optical rotation of -120.0. After mutarotation what is the…

A: Reducing sugar shows a change in the optical rotation when one pure anomer is dissolved in an…

Q: If a solution of a compound (50.0 g/100 mL of solution) has a measured rotation of +150 in a 2 dm…

Q: Solution A contains 9 g of pure (-)-fructose was diluted to 500 mL with water and placed in a…

Q: =rcise 2 Calculate the specific rotation of a compound of molecular weight 150 gm/mole if a 1.0M…

A: “Since you have asked multiple question, we will solve the first question for you. If youwant any…

Q: The specific rotation of the pure (S) form of effluvium is -25.0°. Efflivium is an expensive…

A: Racemic effluvium + Enantiomerically pure effluvium ----> Resultant Drug Specific rotation of…

Q: Consider a solution that contains 74.0% R isomer and 26.0% S isomer. If the observed specific…

Q: The specific rotation for a pure enantiomer is known to be-45 g mL-1 dm-1. A sample containing both…

A: For this sample, specific rotation [a] [a] = observed rotationconcentration ×length[a] =…

Q: A natural product was isolated in the laboratory, and its observed rotation was +10° when measured…

A: Given, The observed rotation is +10° Length of the tube is 1 dm Concentration of the sample is 1.0…

Q: Calculate the specific rotation of a pure sample of a secondary alcohol that gave an observed…

Q: A new chemical reaction produced a mixture of two enantiomers. When 9.0 g of this mixture was…

A: The percentage of (+) and (-) enantiomers produced in the reaction is to be found out. For this the…

Q: A 1.50 g sample of coniine, the toxic extract of poison hemlock, was dissolved in 10.0 mL of ethanol…

A: Introduction : We have to calculate [α]D for coniine .

Q: Consider a solution that contains 69.0% R isomer and 31.0% S isomer. If the observed specific…

A: The solution contains 69.0% of R isomer and 31.0 % of S isomer. Here R isomer is in excess than S…

Q: Q3) (- A solution of 2.0 g of (+)-glyceraldehyde in 10.0 mL of water was placed in a 10.0 cm…

Q: Q. A sugar solution was prepared by as 10.0 g/100 ml, has a measured rotation of +35° in a 4.5 cm…

Q: (c) If the specific rotation of an enantiomeric mixture is +12.5° and that of the pure enantiomer is…

A: Given that, Specific rotation of an enantiomeric mixture = +12.5° Specific rotation of pure…

Q: Consider a solution that contains 84.0% R isomer and 16.0% S isomer. If the observed specific…

A: Given, A solution contain 84.0% R isomer and 16.0% S isomer. The observed specific rotation is -37.…

Q: A solution of (S)-2-butanol (molar mass = 74.12) is observed to have a rotation in a 10 cm path…

A: Since your question has multiple parts, we will answer the first question for you. If you want…

Q: Dextromethorphan has a specific rotation of +142°. If an optically impure sample of dextromethorphan…

Q: the specific rotation of sucrose is 66.5(°cm^3)/(gdm), what is its molar rotation? Mr sucrose is 342

Q: How can you decide whether an observed rotation of a solution of an optically active compound is…

A: Optically active compound: Some chemical compounds have the capability to rotate the plane-polarized…

Q: what is the specific rotation of the compound?

Q: A 0.26 M solution of an enantiomerically pure chiral compound D has an observed rotation of +0.197°…

Q: If a sample of 2-butanol has a specific rotation of +3.25o, determine the %ee and the molecular…

Q: The observed rotation of 2.0 g of a compound in 50 mL of solution in a polarimeter tube 20 cm long…

A: Specific rotation is a property of a chiral compound. It is defined as change in orientation per…

Q: A 0.100 M solution of an enantiomerically pure chiral compound D has an observed rotation of +0.22…

A: Since you have asked multiple questions we will some the first one for you, if you want answer to a…

Q: A solution of 2.0 g of (+)-glyceraldehyde, HOCH2CHOHCHO, in 10.0 mL of water was placed in a 100-mm…

A: Given : Observed rotation = +1.74° Length of the tube = 100 mm = 10 cm = 1 dm…

Q: The specific rotation, [a], for sucrose is +67. What is the observed rotation for a solution of 0.70…

A: Given : Specific roation of sucrose = +67 mass of sucrose = 0.70 gvolume of water = 10 mLpath length…

Q: The specific rotation of optically pure adrenaline in water at 25°C is -53. If a chemist has a…

A: The absolute difference between the mole fraction of two enantiomers is termed as enantiomers. Let…

Q: The specific rotation of (R)carvone is -61o. A chemist prepared a mixture of (R)-carvone and…

Q: The specific rotation for (-)-methylphenidate is -38° mL g¹ dm¹. Path length of the polarimeter is 1…

A: Given , Specific rotation of (−)-methylphenidate = - 38°mLg dm path length of polarimeter = 1 dm

Q: (R)-Camphor [a]20, = +44.0°/(g/mL)dm %3D A researcher places a 0.5 g/mL sample of camphor into a 1.0…

A: The formula for the enantiomeric excess, ee, is

Q: 3. A solution of enantiomers has an observed specific rotation of +8.0°ml/g dm and pure (+)…

Q: If a pure R isomer has a specific rotation of –126.0°, and a sample contains 70.0% of the R isomer…

Q: A 1.62 M solution of (R)-2-butanol is mixed with an equal volume of a 0.810 M solution of racemic…

A: A numerical problem based on concentration terms, which is to be accomplished.

Q: Calculate the e.e. and the specific rotation of a mixture containing 6.0 g of (+)@butan@2@ol and 4.0…

A: Enantiomeric excess (ee) can be defined as a measure of purity which is used for chiral substances.…

Q: Calculate the specific rotation of 120mL methyl salicylate (C8H8O3) if the molar rotation is -1.50°.…

A: MW of salicylate is 152 Molar rotation is -1.50°

Q: The specific rotation of (S)-2-butanol is +135 IF100 g of its enantiomer is dissolved in 100 ml of…

Q: 2. The specific rotation of (S)-carvone (at 20°C) is +61. A chemist prepared a mixture of…

A: Given -> Specific rotation of (S)-carvone = +61 Observed rotation of mixture =-55°

Q: The specific rotation for (-)-methylphenidate is -38° mL g¹ dm¯1. Path length of the polarimeter is…

Q: What is the enantiomeric excess of a solution with a specific rotation of - 90 degree where the pure…

Q: A solution of 0.50 g of (-)@epinephrine dissolved in 10.0 mL of diluteaqueous HCl was placed in a…

A: The specific rotation is given by formula, The molarity of the solution is calculated using grams…

Q: A 1.50 g sample of coniine, the toxic extract of poison hemlock, was dissolved in 10.0 mL of ethanol…

Q: Find the optical purity of a sample that has an observed rotation of +4.5o and a specific rotation…

A: In this question, we will determine the optical purity ( also called percentage of enantiomeric…

Q: Calculate the specific rotation of (2R,3R)-tartaric acid based on the following observation: A 0.856…

A: Given: Mass of pure acid, m = 0.856 g Volume of water, V = 10.0 mL…

Concept explainers

Stereochemistry and Isomerism

Stereochemistry deals with the three-dimensional structure and properties of molecules. It explains the arrangement of atoms and their manipulation within a molecule in a 3D structure. Stereochemistry can be dealt with all types of molecules. Based on the stereochemistry of a molecule, the physical and chemical properties of the molecules vary.

Question

When 0.066 g of cholesterol is dissolved in 1.00 mL of ether and placed in a sample cell 10.0 cm in length, the observed rotation
20°C (using the D line of sodium) is -0.208°Calculate the specific rotation of cholesterol.
specific rotation [a] =
i
eTextbook and Media

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

2. The observed rotation of a compound, X (14.0g dissolved in water to make 100ml. of solution) in a polarimeter tube of length 30cm is +10.5°. What is the specific rotation of X?
1. When 0.247 g of monosodium glutamate (MSG) is dissolved in 10.0 mL of water and placed in a sample cell 10.0 cm in length, the observed rotation at 20°(using the D line of sodium) is +0.632°. Calculate the specific rotation of MSG. 2. When 0.095 g of cholesterol is dissolved in 1.00 mL of ether and placed in a sample cell 10.0 cm in length, the observed rotation at 20°C (using the D line of sodium) is -0.299°.Calculate the specific rotation of cholesterol.3. The specific rotation of L-dopa in water (at 15°C) is -39.5. A chemist prepared a mixture of L-dopa and its enantiomer, and this mixture had a specific rotation of -34. Calculate the % ee of this mixture. 4. The specific rotation of vitamin B7 in water (at 22°C) is +92. A chemist prepared a mixture of vitamin B7 and its enantiomer, and this mixture had a specific rotation of +18. Calculate the % ee of this mixture.
View Policies Current Attempt in Progress When 0.234 g of monosodium glutamate (MSG) is dissolved in 10.0 mL of water and placed in a sample cell 10.0 cm in length, the observed rotation at 20°(using the D line of sodium) is +0.599°. Calculate the specific rotation of MSG. specific rotation = [a] = i eTexthook and Media
28. Calculate the specific rotation of the following compound taken at 25°C using the sodium D line: 1g of sample is dissolved in 20mL of ethanol, the measurement was carried out in 20-cm polarimeter tube, and the observed rotation was equal to 1.25° counterclockwise. A -12.5° 29 Pradios B -22.5° C +12.5° D -0.25° с E -122.5° D F-36.0° G -1.25⁰
If a substance is known to have a specific rotation of -89.3 deg mL/g dm, what is the concentration (in g/mL) of a solution that would give an observed rotation of -25.5 degrees, if the path length of the sample tube was 2.00 dm? (Hint: Rearrange the specific rotation calculation formula)
The observed rotation for 100 mL of an aqueous solution containing 1 g of sucrose, placed in a 2-decimeter sample tube, is +1.33 degrees at 25 degrees C (using sodium lamp). Calculate the specific rotation of sucrose.
The specific rotation, [a]p, for (-)-malic acid is -27. What is the observed rotation for a solution of 1.2 g of (-)-malic acid in 10 mL of water in a sample tube having a pathlength of 10 cm? | degrees. The observed rotation of a solution of 1.2 g of a compound in 10 mL of water is +0.75 degrees. If the pathlength is 10 cm, what is the specific rotation of the compound? 9 more group attempts remaining Submit Answer Retry Entire Group
The observed rotation of a solution of 1.2 g of a compound in 10 mL of water is +0.75 degrees. If the pathlength is 10 cm, what is the specific rotation of the compound?
An enantiopure naturally occurring sugar had a specific rotation of +136. A synthetic sample of this sugar gave a rotation of +84°, when a sample of concentration 1.37 g/100 ml was placed in a cell with a path length of 20 cm. (i) Which of the following prefixes could be used to describe this compound (on the basis of the information provided) +/-, d/l, D/L, R/S? (ii) Calculate the ee of the synthetic sample.
When 0.018 g of cholesterol is dissolved in 1.00 mL of ether and placed in a sample cell 10.0 cm in length, the observed rotation at 20 degrees (Using the D line of sodium) is -0.0567 degrees. Calculate the specific rotation of cholesterol. specific rotation= [α] =
Consider a solution that contains 84.0% R isomer and 16.0% S isomer. If the observed specific rotation of the mixture is −37.0°, what is the specific rotation of the pure R isomer? [a] = = O
CH, CH, Q3: The specific rotation of L-alanine in water (at 25°C) is +2.8. A chemist prepared a mixture of L-alanine and its enantiomer, and 3.50 g of the mixture was dissolved in 10.0 mL of water. This solution was then placed in a sample cell with a pathlength of 10.0 cm and the observed rotation was +0.78. Calculate the % ee of the mixture.