Which of the following is the most likely explanation for an individual who lacks CCR5 as a result of a homozygous defect in the CCR5 gene becoming infected with HIV? a. The mutated CCR5 genes reverted to the normal form, rendering macrophages susceptible to macrophagetropic HIV variants. b. The macrophage-tropic HIV variant entered host cells using CD4 alone. c. The viral nucleic acid alone was taken up by cells, as in cell transformation by bacterial DNA. d. The individual had received a transplant of HIV-infected cells expressing normal CCR5. e. The primary infection involved a lymphocyte-tropic strain of HIV that used CXCR4 as its co-receptor.
Which of the following is the most likely explanation for an individual who lacks CCR5 as a result of a homozygous defect in the CCR5 gene becoming infected with HIV? a. The mutated CCR5 genes reverted to the normal form, rendering macrophages susceptible to macrophagetropic HIV variants. b. The macrophage-tropic HIV variant entered host cells using CD4 alone. c. The viral nucleic acid alone was taken up by cells, as in cell transformation by bacterial DNA. d. The individual had received a transplant of HIV-infected cells expressing normal CCR5. e. The primary infection involved a lymphocyte-tropic strain of HIV that used CXCR4 as its co-receptor.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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| Which of the following is the most likely explanation for an individual who lacks CCR5 as a result of a homozygous defect in the CCR5 gene becoming infected with HIV? |
| a. The mutated CCR5 genes reverted to the normal form, rendering macrophages susceptible to macrophagetropic HIV variants. |
| b. The macrophage-tropic HIV variant entered host cells using CD4 alone. |
| c. The viral |
| d. The individual had received a transplant of HIV-infected cells expressing normal CCR5. |
| e. The primary infection involved a lymphocyte-tropic strain of HIV that used CXCR4 as its co-receptor. |
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