Which of the following is/are TRUE about ion channels and membrane pumps? a) lons can only move through ion channels down a gradient, while pumps can move ions against their gradients. b) lon channels are single-pass transmembrane proteins, while pumps consist of transmembrane proteins that cross the membrane multiple times. O c) lon channels mediate only passive diffusion, while pumps must hydrolyze ATP to move ions. d) a and c e) a, b and c
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- Describe the contribution of each of the following to establishing and maintaining membrane potential: (a) the Na+K+ pump, (b) passive movement of K+ across the membrane, (c) passive movement of Na+ across the membrane, and (d) the large intracellular anions.Which of the following is ther eason why the potassium leaves the cell readily at the peak of the action potential?A) The sodium-potassium pumps work hard to return potassium to the extracellular fluid. B) Diffusion will continue to push potassium into the cell, but electrostatic pressure will move potassium out of the cell. C) Diffusion will push potassium out of the cell, but electrostatic pressure continues to attract potassium to the interior of the cell. D) Both diffusion and electrostatic pressure will cause potassium to exit the cell.Glucose transport across cell membranes varies depending upon blood glucose levels. When glucose levels are high, glucose transport is accomplished via membrane transporters. When glucose concentrations are low, the transport of glucose across the membrane is dependent upon the sodium ion concentration. What types of transport is observed for glucose? A)simple diffusion at high [glucose], secondary active transport at low [glucose] B)facilitated diffusion at high [glucose], secondary active transport at low [glucose] C)simple diffusion at high [glucose], primary active transport at low [glucose] D)facilitated diffusion at high [glucose], primary active transport at low [glucose]
- Which of the following statements about the sodium-potassium pump is correct? A) Both sodium and potassium move down their concentration gradient across the membrane B) 2 sodium ions are pumped out of the cell against their concentration gradient C) The sodium-potassium pump is a type of cotransport. D) ATP is used as an energy sourceTypically, there is an ion gradient between the cytoplasm and the interior of synaptic vesicles. The ion gradient has a functional role. Which of the following statements best describes the ion gradient across the synaptic vesicle membrane and its role? a.) There is a proton gradient across the synaptic vesicle membrane, and it provides the driving force for the transport of neurotransmitter into the vesicle. b.) There is a sodium gradient across the synaptic vesicle membrane, and it provides the driving force for the transport of neurotransmitter into the vesicle. c.) There is a proton gradient across the synaptic vesicle membrane, and it provides the driving force for the transport of neurotransmitter out of the vesicle. d.) There is a sodium gradient across the synaptic vesicle membrane, and it provides the driving force for the transport of neurotransmitter out of the vesicle.Define the terms (i) facilitated diffusion, (ii) primary active transport and (iii) secondary active transport. Identify which of these transport types the following are examples of: a) ATP/ADP translocase b) K^+ channels c) Bacteriorhodopsin
- Which statement is TRUE regarding the Na+ voltage-gated channel in neurons? A) Similar to the potassium ion channel, it exists as a tetramer in the membrane. B) Aspartate residues are part of the voltage-sensing helices. C) Positive membrane potentials on the extracellular side will close the channel. D) Ion specificity comes from the voltage-sensing helices.The resting membrane potential…A) Can be approximated using the Goldman-Hodgkin-Katz equation.B) Represents a difference in charges across the cell membrane, resulting mostly from the passive flow of Na+ions.C) Has no influence on the driving force that acts on different ions across the cell membrane.D) Is equally dependent on the concentration gradients of potassium and sodium across the cell membrane.E) Becomes hyperpolarized during an excitatory graded potential.Which type of membrane transporter could move molecules against their concentration gradient (low to high) a) Carrier proteins b) Leak channel proteins c) Ligand-gated channel proteins d) All of the above
- Which of these answers explains why synaptic vesicles only releasee their neurotransmitter cargo in response to a signal? A) the necessary Rab proteins are not synthesized until an action potential arrives B) vesicle formation at the trans-Golgi network cannot occur in the absence of plasma membrane depolarization C) an additional protein, synaptotagmin, makes vesicle fusion dependent on the calcium concentration D)a plasma membrane transporter is needed to actively pump neurotransmitter into the synaptic cleft. These are inactive until membrane depolarizationA red blood cell with an intracellular fluid (ICF) concentration of 280 mmol/L, is placed into an environment were the concentration of the extracellular fluid (ECF) is 305 mmol/L. As a result, water will move across the cell/plasma membrane. a) Name the process by which water moves b) Describe the overall direction of movement of the water. Answer choices: (i) From outside the cell to inside the cell (ii) From inside the cell to outside the cell, or (iii) Equally, into and out of the cell iii Explain your reasoning for your answer to part (c). 1In your answer you must describe the environment on both sides of the membrane, and use 3 of the following 4 terms correctly; hypertonic, hypotonic, lower solute concentration, higher solute concentrationn (2pts -Correct use of biological terminology, and correct spelling is essential. Edit View Insert Format Tools Table 12pt v Paragraph BIUA ...Ouabain is a specific inhibitor of the active transport of sodium ions out of the cell and is therefore a valuable tool in studies of membrane transport mechanisms. Which of the following processes in your own body would you expect to be sensitive to inhibition by ouabain? Explain your answer in each case. a) Facilitated diffusion of glucose into a muscle cell b) Active transport of dietary phenylalanine across the intestinal mucosa c) Uptake of potassium ions by red blood cells d) Active uptake of lactose by the bacteria in your intestine