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- Select the most accurate answer: HHV-8: A. Is a human herpesvirusB. Affects the immunosuppressed patientC. Is oncogenic, causing Kaposi’s sarcoma (KS), primary effusion lymphomaD. In post-transplant patients who develop KS, it appears to be due to reactivation of HHV-8E. The transmission of HHV-8 has been associated with organ transplants and injection drug useF. All of the aboveA 3-year-old girl was admitted with a diagnosis of acute lymphocytic leukemia. After admission, she was treated by administration of packed red cells, 2 units of platelets, IV fluids, and allopurinol. On the second hospital day, chemotherapy was begun, using IV vincristine and prednisone and intrathecal injections of methotrexate, prednisone, and cytosine arabinoside. She was discharged for home care 5 days later. She was continued on prednisone and allopurinol at home. She received additional chemotherapy 1 month later (11/1) and again on 11/14. On 12/6, she was readmitted because she had painful sores in her mouth and was unable to eat. LABORATORY RESULTS 10/1 10/2 10/3 10/4 11/14 12/6 6/20 Urea N 12.0 ** ** 15 4.0 2.0 ** (mg/dL) Creatinine 0.7 (mg/dL) 0.7 0.7 ** ** 1.0 ** Uric acid (mg/dL) 9.2 ** 12.0 4.0 1.9 2.3 3.1 WBC 56,300 3,700 ** ** ** 2,800 3,700 (mm2) **indicates test not performed Questions: 1. How would you explain the significant elevations of uric acid on admission? 2.…All transplant drugs have the same drug advisory, this is to use with caution when administering them in combination with another immunosuppressant due to the increased risk for: Edema Anemia Nausea and Vomiting Infection
- Which link in the chain of infection is the intervention described below meant to break? Having moderate-to-severe asthma may increase your risk for severe illness from COVID-19. Actions you take should include: Follow your Asthma Action Plan. Continue your current medicines, including any inhalers with steroids in them. Make sure that you have at least a 30-day supply of your medicines. Avoid your asthma triggers. (https://www.cdc.gov/coronavirus/2019- ncov/need-extra-precautions/people-with-medical-conditions.html) Means of transmission Infectious agent Susceptible host Portal of entryWhat is the immunologic manifestation of: 1. Compliment deficiency 2. Myeloperoxidase 3. Reticular dysgenesisexplain these as an Immunotherapeutic approach for cancer therapy, 1. MONOLOCAL ANTIBODIES, 2. CHECKPOINT INHIBITORS, 3. CYTOKINES 4. CANCER VACCINES, 5. ADOPTIVE CELL THERAPY ( CAR T- CELL THERAPY) EXPLAIN EACH WITH ALL DETAILS ALL DETAILS NEEDED. I WILL DISLIKE IF IT’s SHORT ANSWER. OTHERWISE I WILL RATE :)
- In some cases antibodies from individuals who have recovered from COVID-19 are being used as treatment for individuals who are infected with COVID-19. We know from history that these antibodies could provide immunity for those now afflicted with the disorder. While this is great, there could, initially be problems with this treatment plan. Explain, how/ why this could work and discuss at least one specific problem that might be encountered using this treatment method.The clinical course of this disease progresses in three stages. During the acute phase, the child is treatec with intravenous immunoglobulin and: 1. Aspirin to reduce thrombosis formation that may occur within coronary artery aneurysms 2. Ibuprofen to reduce inflammation of the vascular system 3. Dialysis to remove the toxins resulting from concurrent renal failure - Plasma infusions to decrease the polycythemiaSelect the most accurate answer: (please answer all the questions) 1) Kaposi sarcoma (KS) is a cancer that causes patches of abnormal tissue to grow under the skin, in the lining of the mouth, nose, and throat, in lymph nodes, or in other organsA. TrueB. False 2) HHV-8A. Is a human herpesvirusB. Affects the immunosuppressed patientC. Is oncogenic, causing Kaposi’s sarcoma (KS), primary effusion lymphomaD. In post-transplant patients who develop KS, it appears to be due to reactivation of HHV-8E. The transmission of HHV-8 has been associated with organ transplants and injection drug useF. All of the above
- A 45-year-old woman has just tested positive for BRCA1. She has a family history of breast cancer and lost her mother at the age of 50 from breast cancer. She has been receiving yearly mammograms, but now with this discovery of the BRCA1, she is even more concerned about her risk factors for developing breast cancer. What should the nurse discuss with her regarding risk factors?Above in the answer is mentioned " acute lymphoblastic leukaemia (ALL) affects the bone marrow and blood. Overproduction of lymphoblasts, which are immature white blood cells" after I did my research i found out the same that patients with ALL have elevated WBC count, due to this patient presenting with low WBC count (1x10^9/L) Could it be possible that they are suffering from another malignancy rather then acute lymphoblastic leukemiaRewrite the following sentences after correction: 1. The N1303k mutation in the CFTR gene of CF patients is autosomal dominant disorder due to insertion of asparagine at 1303. 2. If a person RBCs have B surface antigen and it will clump with antigen B such clumping indicates blood type B. 3. Indirect ELISA can detect polygenic gene expression.
