Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. H3C. NH2 HCI/H₂O reflux
Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. H3C. NH2 HCI/H₂O reflux
Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter20: Acidity And Pka Of Phenols
Section: Chapter Questions
Problem 11E
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![Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate
as it is first formed in the following reaction.
H3C.
...
NH2
HCI/H₂O
reflux
• You do not have to consider stereochemistry.
• Include all valence lone pairs in your answer.
• Do not include counter-ions, e.g., Na+, I, in your answer.
• In cases where there is more than one answer, just draw one.
+
4
n [
?](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd6d74daf-b9d0-4d49-b577-093d2bde6ada%2Fccd73257-5563-4e39-af19-637c4cd10d71%2Fs85cp8d_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate
as it is first formed in the following reaction.
H3C.
...
NH2
HCI/H₂O
reflux
• You do not have to consider stereochemistry.
• Include all valence lone pairs in your answer.
• Do not include counter-ions, e.g., Na+, I, in your answer.
• In cases where there is more than one answer, just draw one.
+
4
n [
?
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