His388 Glu357 His388 Glu357 Ring opening Proton HO HO abstraction HO G6P His388 Glu357 His388 His388 Glu357 Glu357 HO HO OH ci-enediol intermediate F6P Ring closare Describe the mechanism shown above for phosphoglucose isomerase. • Describe the chemistry of each step · How the enzyme appears or might facilitate the chemistry • How the enzyme increases the reaction rate.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 25P: Using the ActiveModel for phosphofructokinase (Trypanosoma), describe the difference between the...
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His388
Glu357
His388
Glu357
Ring opening
Proton
HO
HO
abstraction
HO
но-
G6P
He
NH-
NH
His388
His388
His388 Glu357
Glu357
Glu357
HO
но
HO
но-
но
OH
cis-enediol
F6P
Ring closure
intermediate
OH
Describe the mechanism shown above for phosphoglucose isomerase.
Describe the chemistry of each step
• How the enzyme appears or might facilitate the chemistry
How the enzyme increases the reaction rate.
Transcribed Image Text:His388 Glu357 His388 Glu357 Ring opening Proton HO HO abstraction HO но- G6P He NH- NH His388 His388 His388 Glu357 Glu357 Glu357 HO но HO но- но OH cis-enediol F6P Ring closure intermediate OH Describe the mechanism shown above for phosphoglucose isomerase. Describe the chemistry of each step • How the enzyme appears or might facilitate the chemistry How the enzyme increases the reaction rate.
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