Identify the enzyme involved in this reaction from the Glycolytic pathway. OPO32 H+OH CH₂OPO3²- O hexokinase O phosphofructokinase-1 O pyruvate kinase O phosphoglycerate kinase ADP ATP coo- H+OH CH₂OPO3²-
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- Which reaction below in the glycolytic pathway has a highly unfavorable delta Gº' but a favorable delta G under physiological conditions? 1,3-Bisphosphoglycerate + ADP3-Phosphoglycerate + ATP O2-phosphoglyerate → phosphoenolpyruvate Ofructose-1,6-bisphosphate dihydroxyacetone phosphate + glyceraldehyde-3-phosphate Ofructose-6-phosphate → fructose-1,6-bisphosphateBelow is an image of the Krebs cycle: acetyl-CoA oxaloacetate COASH H20 NADH NAD* H20 malate citrate fumarate isocitrate FADH2 NAD* CO2 FAD АТР NADH + ADP succinate GTP NAD+ a-ketoglutarate H20 GDP NADH + CO2 COASH succinyl CoA COASH Consider the conversion of succinate to fumarate, which is coupled with the production the electron carrier FADH2. If this reaction was NOT coupled with the production of FADH2 (and only catalyzed the conversion of succinate to fumarate), how would this impact ATP production through cell respiration? OATP production would stop because no high energy electron carriers would be produced ATP production would still occur, but there would be a much lower ATP yield because a large number of electron carriers are no longer being made ATP production would stop because without FADH2 we will no longer have electrons moving through the electron transport chain ATP production would still occur, but there would be a slightly lower ATP yield because a small number of…Indicate the general type of enzyme that mediates each glycolysis reaction depicted below. (e.g. Transferase, Oxidoreductase, Kinase, Hydrolase, Lyase, or Isomerase) iii. O H Glyceraldehyde-3-phosphate → 1,3-Bisphosphoglycerate H-C-OH + NAD CH₂O-P + P₁ H-O- -C-H Glucose →→ Glucose-6-phosphate H b 0 OH HO OH H-C- 0 -H HO- H ОН H-C-OH + NADH +H+ CH₂O P P ATP ADP 1 H (P-O- -C- H H HO OH 2-Phosphoglycerate → Phosphoenolpyruvate 0 OH H ОН -O~(P) + HOH
- The coenzyme NAD+ is required for which glycolytic reaction shown below? Oglyceraldehyde-3-P→ 1,3-bisphosphoglycerate glucose glucose-6-P fructose-6-P→ fructose-1,6-BP 2-phosphoglycerate → phosphoenolpyruvateWhat enzyme catalyzes the conversion of fructose 1,6-bisphosphate to fructose 6-phosphate? O fructose 2,6-bisphosphatase O phosphofructokinase-2 O fructose 1,6-bisphosphatase O phosphofructokinase-1Which of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinase
- Identify the label in the correct position in the following: C-1 of acetyl CoA to malate (one cycle) 3-14C OAA + unlabeled acetyl-CoA to succinate.Which of the following glycolytic enzymes must consume ATP during phosphorylation of its preferred substrate molecule? phosphoglycerate mutase pyruvate kinase succinate dehydrogenase hexokinase phosphoglycerate kinaseWhich reaction is irreversible? oxidized glutathione + NADPH + H+ → reduced glutathione + NADP+ ribulose 5-phosphate → ribose 5-phosphate glucose 6-phosphate + NADP+ → 6-phosphoglucono-δ-lactone + NADPH + H+ sedoheptulose 7-phosphate + glyceraldehyde 6-phosphate → fructose 6-phosphate + erythrose 4-phosphate ribulose 5-phosphate → xylulose 5-phosphate
- Relate the names and function and functions of the following glycolytic enzymes to steps in the process of glycolysis 1. Phosphofructokinase 2. Phosphoglyceromutase 3. Triosephosphate isomerase 4. Enolase 5. HexokinaseThe enzyme that catalyzes reaction below can be classified as: CoO COO NAD+ NADH + H* Но- | malate -C- H-Ć- dehydrogenase Охaloacetate Malate isomerase lyase hydrolase oxidoreductase ligase transferaseIn class, I mentioned that fructose is metabolized differently in the liver compared to glucose. Refer to the figure shown below to calculate the number ofATPs you would expect from the metabolism of fructose in the liver. Show your work! Fructokinase Fructose Fructose-1-P АТР ADP Aldolase B Dihydroxy- acetone phosphate Glyceraldehyde АТР Triose kinase Triose phosphate isomerase ADP 4 - Glyceraldehyde-3-P Glycolysis Руruvate Acetyl-CoA Fatty acids and triglycerides