Question 1a. What is the direction of shift of a dose-response curve when a reversible competitive antagonist is present at a fixed concentration?
- Up
- Down
- Left
- Right
- Down and right
Question 1b. When the antagonist is competitive and reversible how does the Emax change?
- It is unchanged
- It is increased
- It is decreased
Question 1c. When the antagonist is competitive and reversible how does the ED50 change?
- It is unchanged
- It is increased
- It is decreased
Question 2a. What is the direction of shift of a dose -response curve when an irreversible competitive antagonist is present at a fixed concentration.
- Up
- Down
- Left
- Right
- Down and right
Question 2b. When the antagonist is competitive and irreversible how does the Emax change?
- It is unchanged
- It is increased
- It is decreased
Question 2c. When the antagonist is competitive and irreversible how does the ED50 change?
- It is unchanged
- It is increased
- It is decreased
Question 3a. What is the direction of shift of a dose -response curve when a non-competitive antagonist is present at a fixed concentration.
- Up
- Down
- Left
- Right
- Down and right
Question 3b. When the antagonist is non-competitive how does the Emax change?
- It is unchanged
- It is increased
- It is decreased
Question 3c. When the antagonist is non-competitive how does the ED50 change?
- It is unchanged
- It is increased
- It is decreased
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