Answered: 1. The following data were obtained for… | bartleby

Curren'S Math For Meds: Dosages & Sol

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter21: Heparin Infusion Calculations

Section: Chapter Questions

Problem 1.3P

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CHEM151/251
Biochemistry 1
a. Determine Km
1. The following data were obtained for a competitive inhibition study in which the [I] = 3 µM for each
determination of vo in the presence of inhibitor. The Vmax = 200 μM P/min for both data sets.
200
Vo (UM P/min)
8 8 8 8 8 8 8 8 8
180
160
140
120
100
40
Name (Print)/ID #:
the absence of inhibitor.
Participation Question # 10
No Inhibitor
50
+Inhibitor
100
[Substrate] (UM)
150
b. Determine Km, app for the data obtained in presence of inhibitor.
200
c. Calculate the value for Ki. Note: a = 1 + [I]/Ki and a¹ = 1 + [I]/Ki*.
for the data obtained in

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