6. You are performing site-directed mutagenesis to test predictions about which residues are critical for the function of a protein. Which of each pair of amino acid substitutions below would you expect to disrupt protein structure the most? Briefly explain your answers. (a) Ile replaced by Leu or Tyr (b) Val replaced by Ala or Phe (c) Lys replaced by Asp or Arg

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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6. You are performing site-directed mutagenesis to test predictions about which residues are critical for
the function of a protein. Which of each pair of amino acid substitutions below would you expect to
disrupt protein structure the most? Briefly explain your answers.
(a) Ile replaced by Leu or Tyr
(b) Val replaced by Ala or Phe
(c) Lys replaced by Asp or Arg
Transcribed Image Text:6. You are performing site-directed mutagenesis to test predictions about which residues are critical for the function of a protein. Which of each pair of amino acid substitutions below would you expect to disrupt protein structure the most? Briefly explain your answers. (a) Ile replaced by Leu or Tyr (b) Val replaced by Ala or Phe (c) Lys replaced by Asp or Arg
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Introduction 

Proteins are complex biomolecules that play a crucial role in the functioning of cells and tissues. They are made up of chains of smaller units called amino acids, which are linked by peptide bonds. The order of the amino acids determines the specific three-dimensional structure of each protein, which in turn determines its function.

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