After performing a plate and liquid lysate, it was found that the plate lysate achieved the common titre range of 1010-1011 pfu/ml whereas the liquid lysate achieved a range of 108 PFU/mL; what is the reason for the lower titre in different methodologies? How can we troubleshoot this issue in the future?

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 7.2P
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After performing a plate and liquid lysate, it was found that the plate lysate achieved the common titre range of 1010-1011 pfu/ml whereas the liquid lysate achieved a range of 10PFU/mL; what is the reason for the lower titre in different methodologies? How can we troubleshoot this issue in the future?

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