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Intracellular receptors bind to signaling molecules that are
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A.
anionic.
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B.
cationic.
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C.
nonpolar.
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D.
polypeptides.
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- Which of the following questions regarding second messengers is false? a. They are needed to mediate the action of nonpolar regulatory molecules. b. They are released from the plasma membrane into the cytoplasm of cells. c. They are produced in response to the binding of regulatory molecules to receptors in the plasma membrane. d. They produce the intracellular actions of polar regulatory molecules.Paracrine signaling is characterized by ligands that are a. produced by the cell itself. b. secreted by neighboring cells. c. present on the plasma membrane of neighboring cells. d. secreted by distant cells.Carbon monoxide is a deadly gas. This is due to its quick activation of specific signaling pathways in cells of our body. Since this is a gas, it most likely uses.... Select one: a. A transmembrane cell surface receptor since it cannot pass through cell membranes b. A voltage-gated ion channel receptor since it creates a charge when crossing the cell membrane c. An intracellular receptor since it can easily diffuse across a membrane
- A biochemist is designing a new drug that will mimic the shape and function of a particular intercellular signaling molecule. Therefore she must produce a molecule that will bind to the receptor protein and... A. produce a cellular response by altering the Na+/K+ pump located near the receptor site. B. induce a change in the receptor molecule shape, which will ultimately prevent a cellular response. C. induce a change in the receptor molecule shape, which will ultimately produce a cellular response. D. induce a change in the phospholipid bilayer that causes a polar reversal allowing the molecules to be endocytose (engulfed).Hydrophobic signaling molecules act by a. binding to plasma proteins b. starting second messenger systems c. binding to receptors inside the cell d. starting action potentialsWhich of the following are methods of cellular signaling? Select one: a. All the answers are correct. b. Connections through fibers of the ECM from one cell to another c. Ligand binding to a receptor in the cell membrane d. Desmosomes ‘pulling’ one cell to another e. Lipid or gas ligand binding to an intracellular receptor
- What type of cell signaling receptor is depicted below a. Cytoplasmic Receptor b. Transmembrane Receptor c. Intracellular Receptor d. Nuclear ReceptorWhat is a key characteristics of a G protein-linked receptors? a. it allows ions to flow through b. it changes confirmation and becomes autophosporylated c. it is a serpentine transmembrane receptor?Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium. They have an important role in vascular homeostasis. Endothelin activates G protein-coupled receptors (GPCRs) ETA or ETB on a target cell. Which subunit of heterotrimeric G protein is released when the receptor is activated? a.) gamme b.) beta c.) alpha
- A ligand binds to the extracellular portion of a receptor. Another ligand binds to an identical half of the same receptor. When this happens, the two halves come together and the intracellular portion adds phosphates from ATP to tyrosine amino acids it the receptor structure. This passage describes what kind of receptor? Select one: a. A G-protein coupled receptor b. A receptor tyrosine kinase c. A receptor tyrosine phosphatase d. A ligand-gated kinase channelInsulin is a peptide (protein) hormone. As such, which of the following would be the most likely receptor for this signaling hormone? Select one: a. A transmembrane receptor in the cell membrane b. An intracellular receptorIdentify which of the following statements is a lie? Select one: a. The docking of ligands to the receptor causes receptor-associated proteins to activate another protein to continue the signaling cascade and one example of this event is the binding of epidermal growth factor (EGF) to the EGF receptor . b. Ligands are important to initiate signal Transduction pathway. c. Ligands detach from the cell surface receptor in order to change the conformation of the receptor and initiate the signaling pathway.