The drug troglitazone was used to treat diabetes but was withdrawn from the market when patients who took the drug suffered from severe side effects. The data below show the activity of an enzyme in the steroid biosynthetic pathway in the presence and absence of 10 µM troglitazone. [S] (µM) v0 (pmol min-1) Create a plot of 1/v0 vs. 1/[S]. Calculate KM and vmax in presence and absence of inhibitor. What type of inhibitor is troglitazone? Clearly support your answer.

The drug troglitazone was used to treat diabetes but was withdrawn from the market when patients who took the drug suffered from severe side effects. The data below show the activity of an enzyme in the steroid biosynthetic pathway in the presence and absence of 10 µM troglitazone. [S] (µM) v0 (pmol min-1) Create a plot of 1/v0 vs. 1/[S]. Calculate KM and vmax in presence and absence of inhibitor. What type of inhibitor is troglitazone? Clearly support your answer.

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter4: Basic Immunology And Immunohematology

Section4.2: Infectious Mononucleosis Tests

Problem 5RQ

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