What is the purpose behind the introduction of the triazole ring in this sedative-hypnotic agent? To produce a more lipophilic longer acting agent To produce shorter-acting agents. To produce the antipsychotic effect O To produce less toxic agents.
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- Which drug is afull agonist at opioid receptors with analgesics activitiy equivalent to morphine, a linger duration of action and fewer with drawal sign on abrupt discontinuance than morphine?? 1-fentanyl 2-methadone 3- NalbuphineWhat are the mechanism of analgesic action of morphine? Briefly explan at your own wordsWhat is the mechanism of analgesic action of morphine? Briefly Explain. explain at your own words
- Why does morphine show less analgesic activity after oral administration? explain at your own wordsWhy does morphine show less analgesic activity after oral administration? Explain at your own words answer?Which of the following groups in the following compound is important for the selectivity of B-adrenoceptors? HO HO O The phenol OH O The amine O The alcohol IZ The tertiary butyl group The hydroxymethylene group
- Give me a figure of the mechanism of analgesic action of morphine?Briefly explain the mechanism of analgesic action of morphine? explain at your own wordsWhen an elderly but active gentleman came in to collect his prescription for zopiclone (3.75mg at night), he seemed anxious and asked if it was longer acting than lormetazepam, whichwas his last hypnotic.He had asked his GP to change to a longer acting hypnotic because he was waking up in themiddle of the night to go to the toilet, not able to go back to sleep. The two hypnotics havesimilar properties but if anything the duration of action of zopiclone is slightly shorter.• The gentleman is 72; he lost his wife 10 months ago and is now living with his daughter’sfamily. She has two teenage girls.1: What issues would you want to explore?2: What would your advice be?3: Why do you think the GP changed the hypnotics?
- What are the therapeutic benefits of Benzodiazepines? list three medications in this classification?Why Benzodiazepine induces tolerance? Please answer at your own words.An individual who has been using a drug for an extendedperiod of time suddenly finds himself unable to securemore of the drug. He acts nervous and irritable and ishyperactive. He seems almost desperate to find more ofthe drug, but experiences no sickness, pain, or other outward physical discomfort. Based on his behavior, whatdrugs might he possibly have been using? Explain youranswer.