What is the usual rate-limiting step for a poorly soluble and highly permeable drug (BCS 2)?

Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter13: The Chemistry Of Solutes And Solutions
Section13.6: Expressing Solution Composition
Problem 13.7PSP
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What is the usual rate-limiting step for a poorly soluble and highly permeable drug (BCS 2)?

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