Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 23, Problem 13P
Summary Introduction

To explain: The reason why segmentation of the genome provides a strong evolutionary advantage for negative strand viruses.

Concept introduction: Negative sense single-stranded RNA virus or negative-stranded virus (NSV) or (-) ssRNA virus are viruses that have RNA as the genetic material as the name suggests, and their RNA is homologous to mRNA. They convert their negative sense into positive sense and then proceed with translation. They have genome segmentation, that is, the genome is present as discrete set of RNA segments as present in influenza virus, rift valley virus, hanta virus, and lassa virus.

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