ANATOMY+PHYSIOLOGY
4th Edition
ISBN: 9781260265217
Author: McKinley
Publisher: RENT MCG
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Chapter 24.5, Problem 17WDYL
Summary Introduction
To determine:
The effect of damage to the filtration membrane on relative permeability of the membrane and on the substances that are filtered.
Concept introduction:
Filtration membrane allows movement of all plasma components through it but not filter blood cells, small protein molecules and it filters out large molecules of proteins, engulfs and degrades macromolecules which are caught in the membrane.
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Students have asked these similar questions
Certain diseases, kidney trauma, heavy metals, and some bacterial toxins can damage the filtration membrane. What effect would this have on relative permeability of the membrane and the substances that are filtered?
Discuss the causes of the increase in fluid level in "vessel A," which is isolated
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The renal handling of a novel drug is being studied. When the drug is present in the blood, it is filtered into the Bowman’s capsule and secreted via transport proteins in the renal tubules, but it is NOT reabsorbed. The lines on the following graph represent filtration, secretion and excretion rates of this drug at various plasma concentrations.
For the three lines shown (labeled A-C) identify which line represents filtration, which line represents secretion, and which line represents excretion
Explain how you determined this.
Chapter 24 Solutions
ANATOMY+PHYSIOLOGY
Ch. 24.1 - Which structure of the urinary system forms urine,...Ch. 24.1 - What are the two means by which the kidney helps...Ch. 24.2 - What tissue composes the fibrous capsule that...Ch. 24.2 - What are the regions of the kidney that drain...Ch. 24.2 - What three anatomic structures of the kidney are...Ch. 24.3 - Prob. 6WDYLCh. 24.3 - Prob. 7WDYLCh. 24.3 - Prob. 8WDYLCh. 24.3 - Differentiate between the function of principal...Ch. 24.3 - What are the two primary cellular components of...
Ch. 24.4 - Prob. 11WDYLCh. 24.4 - What are the three major types of capillaries...Ch. 24.4 - What is the pathway of fluid filtered by the...Ch. 24.5 - How does tubular reabsorption differ from tubular...Ch. 24.5 - How are the components of the filtration membrane...Ch. 24.5 - What is normally filtered across the glomerular...Ch. 24.5 - Prob. 17WDYLCh. 24.5 - What is the value of the NFP if the glomerular...Ch. 24.5 - Prob. 19WDYLCh. 24.5 - If HPg increases, what is the effect on NFP? Is...Ch. 24.5 - Does urine production increase, decrease, or stay...Ch. 24.5 - What are the three factors that regulate...Ch. 24.5 - Prob. 23WDYLCh. 24.6 - What are the significant anatomic and physiologic...Ch. 24.6 - What is the transport maximum of a substance? How...Ch. 24.6 - Prob. 26WDYLCh. 24.6 - Why are proteins said to be transported rather...Ch. 24.6 - How does Na+ reabsorption occur? Which two...Ch. 24.6 - What is the effect of parathyroid hormone on the...Ch. 24.6 - How is the movement of H+ and HCO3 regulated by...Ch. 24.6 - Prob. 31WDYLCh. 24.6 - Prob. 32WDYLCh. 24.6 - Prob. 33WDYLCh. 24.7 - Prob. 34WDYLCh. 24.7 - Prob. 35WDYLCh. 24.8 - Prob. 36WDYLCh. 24.8 - Prob. 37WDYLCh. 24.8 - Prob. 38WDYLCh. 24.8 - Prob. 39WDYLCh. 24 - Prob. 1DYKBCh. 24 - _____ 2. When the kidneys are described as being...Ch. 24 - _____ 3. Which of the following is located within...Ch. 24 - _____ 4. All of the following are capillaries...Ch. 24 - _____ 5. Which of the following is a component of...Ch. 24 - _____ 6. If blood pressure in the glomerulus...Ch. 24 - _____ 7. Which hormone increases Na+ and water...Ch. 24 - _____ 8. If the tubular maximum is exceeded, then...Ch. 24 - _____ 9. The function unique to the nephron loop...Ch. 24 - _____ 10. If antidiuretic hormone (ADH)...Ch. 24 - Trace blood flow into and out of the kidney....Ch. 24 - Describe where filtrate, tubular fluid, and urine...Ch. 24 - Describe the anatomic components of the...Ch. 24 - Prob. 14DYKBCh. 24 - Explain how glomerular filtration rate (GFR) is...Ch. 24 - Discuss the affect of aldosterone and antidiuretic...Ch. 24 - Explain how antidiuretic hormone (ADH) is...Ch. 24 - Describe the significant differences between blood...Ch. 24 - Identify all of the following that are functions...Ch. 24 - Explain the process of micturition.Ch. 24 - Use the following paragraph to answer questions...Ch. 24 - Prob. 2CALCh. 24 - Use the following paragraph to answer questions...Ch. 24 - Martin, a young man of 20, was in a car accident...Ch. 24 - A 19-year-old male named Paul was in a diving...Ch. 24 - A patient with cancer is treated with...Ch. 24 - Prob. 2CSLCh. 24 - Males who suffer from either benign prostatic...
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- Blood volume must be restored in a person who has lost large amounts of blood due to serious injury. This is often accomplished by infusing isotonic NaCl solution into the blood. Why is this more effective than infusing an isoosmotic solution of a penetrating solute, such as urea?arrow_forwardExplain how a high concentration of sodium ions in theinterstitial fluid affects intracellular fluid levels.arrow_forwardExplain the effect of renin on filtration.arrow_forward
- Active transport requires the use of ATP. Identify two ions that require active transport to be selectively reabsorbed.arrow_forwardWhat would happen to plasma and urine osmolarity and urinevolume in a patient with a lung tumor that secretes vasopressin?arrow_forwardthe major difference between plasma and interstitial fluid is the absence of plasma proteins from the interstitial. explain how this affects solute distrbution and what kind of correction you would do it if you were measuring solute concentrationarrow_forward
- One model of the glomerular membrane is a microporous membrane in which right cylindrical pores penetrate all the way through the membrane. Assume that the pores have a length of 50 nm and a radius of 3.5 nm. The viscosity of plasma is 0.002 Pa s. The average hydrostatic pressure in the glomerulus is 60 mm Hg, hydrostatic pressure in Bowman's space is 20 mm Hg and the average oncotic pressure of glomerular capillary blood is 28 mm Hg. A. Calculate the flow through a single pore assuming laminar flow (use the Poiseuille flow equation) B. How many pores would there have to be to produce a normal GFR? C. If the total aggregate area of the kidneys for filtration is 1.5 m2, what is the density of the pores (number of pores per unit area)? D. What fraction of the area is present as pores?arrow_forwardBlood in renal efferent arterioles is compared to systemic arterial blood. hypertonic hypotonic isotonicarrow_forwardGiven the following volumes, calculate the Net Filtration: BP=30 mmHg, IF Osm Pressure=1 mmHg, Blood colloid osm pressure=22 mmHg, IF hydrostatic pressure=0 mmHgarrow_forward
- 1. There is a medical condition called Syndrome of Inappropriate Anti-Diuretic Hormone (SIADH) secretion, which can occur as a result of head trauma. Patients with this condition retain water and present with a volume imbalance. A) Name the type of volume imbalance and accompanying direction of changes in ICF and ECF volumes and osmolality. B) Calculate the changes in osmolality and volumes of extracellular and intracellular fluid compartments if 3 liters of water are retained by a patient with SIADH. You can assume that the patient’s initial volumes were ECF=14 L, ICF=28 L. And his initial body osmolality = 290 mOsM. Remember that the total solute in the ICF compartment is kept in place by the cell membrane barrier.arrow_forwardOne type of diuretic given to people with high blood pressure, renal disease and congestive heart failure are thiazide-type diuretics. These drugs inhibit sodium ion reabsorption by inhibiting the transport in the ascending limb of the loop of Henle. A) What does it mean to inhibit the transport of sodium ions in the loop of Henle? B) Explain how this inhibition of sodium ions in the loop of Henle could help increase urine production.arrow_forwardIf a positive ion is reabsorbed across a kidney membrane: A) A negative ion must be retained in reserve at the membrane B) A negative ion must be secreted across the membrane C) The same positive ion must be passively moved across the membrane D) A different positive ion must be secreted across the membrane E) None of these answers is correctarrow_forward
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