Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 28, Problem 9P
Interpretation Introduction
Interpretation:
The possible application for the drug involved in the cancer chemotherapy which is capable of inhibiting the ABC transporter MDR should be determined.
Concept introduction:
ABC transporters use the ATP binding energy and hydrolysis to transport numerous substrates through the cellular membranes. These ABC transporters can be divided into three chief functional classes. In prokaryotes, importers facilitate the uptake of nutrients into the cell.
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SIGNALS AND TARGETS. Listed below are sample polypeptides/proteins with their signal molecule/peptide. Answer the questions that follow. If you are asked to give the amino acid sequence, provide the sequence using the three-letter names of the amino acids (eg. ser-ala-met).
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