Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 37, Problem 26CTQ
Why is cAMP-mediated signal amplification not required in steroid hormone signaling? Describe how steroid signaling is amplified instead.
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Students have asked these similar questions
In the B-acrenergic receptor signaling pathway where desensitization occurs, what
protein acts as an effector protein?
The activity of the effector protein directly affects the activity of which protein in this pathway?
How would the presence of a GAP affect the desensitization process?
stimulate it
inhibit it
have no effect
What is the actual mechanism by which desensitization occurs?
the receptor is ubiquitinated
the hormone is phosphorylated
the hormone is degraded
the receptor is internalized
In a hypothetical cAMP-mediated signal transduction cascade, the GTP-αs/adenylate cyclase interaction following a single hormone–receptor binding event lasts for 2.3 seconds. The catalytic rate (turnover number) for the adenylate cyclase in question is 350 cAMP molecules produced per second. How many cAMP molecules would be produced if five hormone-receptor binding events were to occur before the hormone molecule dissipates in the bloodstream? What is the amplification effect of this step in the signaling pathway?
Recently, a Gα q-coupled receptor was discovered that mediates at least some of the many activities of estrogen. At the time, this discovery generated considerable controversy, as it ran counter to what was then the understanding of how steroid hormone signaling worked. Which of the following observations might have led the investigators to suspect the existence of this newly discovered receptor?
A.
Activities of estrogen apparent less than 1 minute after application of the hormone
B.
The growth promoting activity of estrogen
C.
The presence of estrogen nuclear receptors in cells not previously known to respond to the hormone
D.
Estrogen is found in much higher concentrations in adult women than adult men
E.
Uptake of estrogen by target cells
Chapter 37 Solutions
Biology 2e
Ch. 37 - Figure 37.5 Heat shock proteins (HSP) are so named...Ch. 37 - Figure 37.11 Pancreatic tumors may cause excess...Ch. 37 - Figure 37.14 Hyperthyroidism is a condition in...Ch. 37 - A newly discovered hormone contains four amino...Ch. 37 - Which class of hormones can diffuse through plasma...Ch. 37 - Why are steroids able to diffuse across the plasma...Ch. 37 - A new antagonist molecule has been discovered that...Ch. 37 - What effect will a cAMP inhibitor have on a...Ch. 37 - When insulin binds to its receptor, the complex is...Ch. 37 - Drinking alcoholic beverages causes an increase in...
Ch. 37 - FSH and LH release from the anterior pituitary is...Ch. 37 - What hormone is produced by beta cells of the...Ch. 37 - When blood calcium levels are low, PTH stimulates:...Ch. 37 - How would mutations that completely ablate the...Ch. 37 - A rise in blood glucose levels triggers release of...Ch. 37 - Which mechanism of hormonal stimulation would be...Ch. 37 - A scientist hypothesizes that the pancreas’s...Ch. 37 - Which endocrine glands are associated with the...Ch. 37 - Which of the following hormones is not produced by...Ch. 37 - Recent studies suggest that blue light exposure...Ch. 37 - Although there are many different hormones in the...Ch. 37 - Where is insulin stored, and why would it be...Ch. 37 - Glucagon is the peptide hormone that signals for...Ch. 37 - Name two important functions of hormone receptors.Ch. 37 - How can hormones mediate changes?Ch. 37 - Why is cAMP-mediated signal amplification not...Ch. 37 - Name and describe a function of one hormone...Ch. 37 - Describe one direct action of growth hormone (GH).Ch. 37 - Researchers have recently demonstrated that...Ch. 37 - How is hormone production and release primarily...Ch. 37 - Compare and contrast hormonal and humoral stimuli.Ch. 37 - Oral contraceptive pills work by delivering...Ch. 37 - What does aldosterone regulate, and how is it...Ch. 37 - The adrenal medulla contains two types of...Ch. 37 - How would damage to the posterior pituitary gland...
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