The extravasation of neutrophils and lymphocytes occurs by generally similar mechanisms, although some differences distinguish the two processes. Which statements are true about lymphocyte extravasation? Naive lymphocytes are confined to the secondary lymphatic system by expression of the surface protein CD62L which recognizes HEV addressins. The adhesion step requires chemokine activation. Extravasation follows the order of chemoattraction, adhesion, rolling, and transmigration. Extravasation follows the order of rolling, activation, adhesion, and transmigration. The transmigration step requires chemokine activation. CCR7 is an essential chemokine receptor that guides lymphocyte extravasation into tissues during an immune response.
The extravasation of neutrophils and lymphocytes occurs by generally similar mechanisms, although some differences distinguish the two processes. Which statements are true about lymphocyte extravasation? Naive lymphocytes are confined to the secondary lymphatic system by expression of the surface protein CD62L which recognizes HEV addressins. The adhesion step requires chemokine activation. Extravasation follows the order of chemoattraction, adhesion, rolling, and transmigration. Extravasation follows the order of rolling, activation, adhesion, and transmigration. The transmigration step requires chemokine activation. CCR7 is an essential chemokine receptor that guides lymphocyte extravasation into tissues during an immune response.
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section: Chapter Questions
Problem 14RE
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