Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 13.1, Problem 1R
Summary Introduction
To review:
The circumstantial evidence in Griffith’s experiment of 1928 that indicated DNA (deoxyribonucleic acid) to be the genetic material.
Introduction:
Griffith conducted experiments on mice utilizing the bacteria Streptococcus pneumoniae in an attempt to discover a method to find a vaccine against this pneumonia-causing bacteria. He used two strains, rough strain (RII) and smooth strain (SIII). The R strain was the avirulent strain, while the S strain was the virulent strain and caused pneumonia.
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Given the state of knowledge at the time of the Avery, MacLeod,and McCarty experiment, why was it difficult for some scientiststo accept that DNA is the carrier of genetic information?
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Life: The Science of Biology
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- Was Pauling’s hypothesized model of DNA In January 1953 “correct”?arrow_forwardHow did Crick and Watson discovered DNA?arrow_forwardWith regard to Chargaff’s experiment described in Figure shown,answer the following:A. What is the purpose of paper chromatography?B. Explain why it is necessary to remove the bases in order todetermine the base composition of DNA.C. Would Chargaff’s experiments have been convincing if theyhad been done on DNA from only one species? Discuss.arrow_forward
- Explain how Avery-MacLeod-McCarty experiment discovered that DNA is the genetic material.arrow_forwardAfter Alfred Hersey and Martha Chase definitively identified DNA as the “Transformative material”, which three scientists were responsible for characterizing the structure of DNA? How did they do it?arrow_forwardWhy wasn’t James Watson punished by the scientific community once more was learned about how he obtained the critical data needed to come up with the structure of DNA?arrow_forward
- Who discovered DNA?arrow_forwardHow griffin's experiment helps in the identification of DNA as the genetic material?arrow_forwardDiscuss the experiments Griffith, Avery and Hershey/Chase did in the early 1920-50s that helped determine DNA was the genetic stuff. What was the “take home” from each?arrow_forward
- Several experiments aided the discovery of DNA being the inheritable material. Which of the following experiments clearly demonstrated DNA, not protein, was the inheritable material?arrow_forwardSeveral rounds of failure often precede most successful scientific discoveries. How did failure play a role in the discovery of the structure of DNA?arrow_forwardWhat background information did waston and crick have made availale for developing a model of DNA? What wastheir contribution?arrow_forward
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