Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 23.1, Problem 1COMQ
Summary Introduction
Introduction:
Chromosome mapping is a technique that is used to find the position of various genes on the chromosomes. It can be done by different methods including, cytogenetic mapping, linkage mapping, and physical mapping. These are done using various techniques.
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Information obtained by microscopic analysis of stained chromosomes is used in: a. radiation hybrid mapping b. sequence mapping c. RFLP mapping d. cytogenetic mapping
When preparing a karyotype, which of the following steps is conducted?a. Treat the cells with a chemical that causes them to begin cell division.b. Treat the cells with a hypotonic solution that causes them to swell.c. Expose the cells to chemical dyes that bind to the chromosomesand stain them.d. All of the above steps are carried out.
1.) Chromosome images are obtained from any cell type that has a nucleus.
2.) Chromosomes can be obtained from reticulocytes.
a. Both are correct
b. Both are incorrect
c. Statement 1 is incorrect. Statement 2 is correct.
Chapter 23 Solutions
Genetics: Analysis and Principles
Ch. 23.1 - Prob. 1COMQCh. 23.2 - Prob. 1COMQCh. 23.3 - A molecular marker is a _____ found at a specific...Ch. 23.3 - 2. Which of the following is an example of a...Ch. 23.3 - To map the distance between molecular markers via...Ch. 23.4 - 1. What is a contig?
a. A fragment of DNA that...Ch. 23.4 - A vector that can carry a large fragment of...Ch. 23.4 - 3. Chromosomal walking is a method of _____ in...Ch. 23.5 - Prob. 1COMQCh. 23.5 - Prob. 2COMQ
Ch. 23.5 - 3. A prokaryotic genome is about 4 million bp in...Ch. 23.6 - Metagenomics is aimed at a. determining the...Ch. 23 - 1. A person with a rare genetic disease has a...Ch. 23 - For each of the following, decide if it could be...Ch. 23 - Which of the following statements about molecular...Ch. 23 - 1. Is each of the following a method used in...Ch. 23 - Prob. 2EQCh. 23 - Prob. 3EQCh. 23 - The cells from a persons malignant tumor were...Ch. 23 - 5. Figure 23.2 describes the technique of FISH....Ch. 23 - Explain how DNA probes with different fluorescence...Ch. 23 - 7. A researcher is interested in a gene found on...Ch. 23 - Prob. 8EQCh. 23 - Prob. 9EQCh. 23 - Prob. 10EQCh. 23 - Prob. 11EQCh. 23 - Prob. 12EQCh. 23 - In the Human Genome Project, researchers have...Ch. 23 - 14. Take a look at question 3 in More Genetic...Ch. 23 - 15. Place the following stages of a physical...Ch. 23 - 16. What is an STS? How are STSs generated...Ch. 23 - 17. Four cosmid clones, which we will call cosmids...Ch. 23 - A human gene, which we will call geneX, is located...Ch. 23 - 19. Describe how you would clone a gene by...Ch. 23 - 20. A bacterium has a genome size of 4.4 Mb. If a...Ch. 23 - 21. Discuss the advantages of next-generation...Ch. 23 - Prob. 22EQCh. 23 - Prob. 23EQCh. 23 - What is a molecular marker? Give two examples....Ch. 23 - Which goals of the Human Genome Project do you...
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- When preparing a karyotype, which of the following steps isconducted?a. Treat the cells with a drug that causes them to begin celldivision.b. Treat the cells with a hypotonic solution that causes them toswell.c. Expose the cells to chemical dyes that bind to the chromosomes and stain them.d. All of the abovearrow_forwardA molecular marker is a found at a specific siteon a chromosome that has properties that allow it to be . a. colored dye, visualized via microscopyb. colored dye, visualized on a gelc. segment of DNA, uniquely identified using molecular toolsd. segment of DNA, visualized via microscopyarrow_forwardWhat are the advantages of real-time PCR over microscopy for diagnosing malaria? a. Giemsa stain is not required for real-time PCR b. It allows for species identification and quantification of malaria-causing plasmodium at lower blood concentration with greater sensitivity and specificity. c. Real-time PCR doesn't require the use of a microscope which is deemed too expensive. d. Real-time PCR has a hiher sensitivity for the main malaria-causing plasmodium, P. falciparum, than microscopy techniques. Thank you!!!arrow_forward
- Which is the proper order of the following steps in a genecloningexperiment involving vectors?1. Add DNA ligase.2. Incubate the chromosomal DNA and the vector DNA with arestriction enzyme.3. Introduce the DNA into living cells.4. Mix the chromosomal DNA and vector DNA together.a. 1, 2, 3, 4 c. 2, 4, 1, 3b. 2, 3, 1, 4 d. 1, 2, 4, 3arrow_forwardHow is homologous recombination for DNA repair different from recombination in meiosis? Choose all correct answers. a. HR in DNA repair requires a double-strand break, but meiotic recombination does not. b. HR in DNA repair requires strand invasion, but meiotic recombination does not. c. HR in DNA repair results in identical chromosomes. Meiotic recombination results in changes to the DNA sequence of the "repaired" chromosomes. d. HR in DNA repair uses a newly synthesized identical chromosome as a template. Meiotic recombination uses a homologous chromosome as a template.arrow_forwardAsaparrow_forward
- When recombination (“crossing over”) doesn’t happen correctly, what type(s) of mutations that can occur? Mark all that apply Select one or more: a. Deletion of part of a chromosome b. Translocation (transfer of part of a chromosome to a non-homologous chromosome) c. Duplication of part of a chromosome d.Inversion (reversal or “flipping” of part of a chromosome)arrow_forwardThe following are techniques that create bands along the length of a chromosome, EXCEPT: A. Quinacrine banding B. Reverse banding C. Giemsa banding D. CBG bandingarrow_forwardA. Aneuploidy refers to the loss or gain a chromosome part. B. Polyploid cells have extra chromosome sets. A) Both statement is correct B) Both statement is incorrect C) First statement is correct, Second is incorrect D) First statement is incorrect, Second is correctarrow_forward
- a. In order to help you visualize the processes, begin by drawing the 4 pictures from question “2" at the appropriate spot by the arrows along the top. b. Using a thin line, graph the relative amount of DNA per nucleus using the LEFT Y axis (G1, S and G2 are graphed for you). c. Using a thick line or different color and the scale on the RIGHT Y axis, graph the changes in Ploidy or sets of information per nucleus. Haploid (1n) means one of each chromosome type. Diploid (2n) means two of each chromosome type. 4x 1n G1 s'G2 P' M'A'T'cG1' s'G2 P' M' A'T C M' A T' C Fert Mitosis Meiosis IMeiosis II Relative amount of DNA per nucleus Ploidy per nucleusarrow_forwardObserve the process of transduction in the image below. Cell 1 is represented by "A," Cell 2 is represented by "B," and Cell 1's DNA is represented by "a." The blue color represents the components of the bacteriophage. 6 Process of transduction. A B m с D 5 Which of the following correctly identifies a process that occurs during transduction? um No n During meiosis, crossing over occurs, which combines the genetic information of Cell A and Cell B. Genetic information is being transferred between bacterial cells using a pilus. Bacterial chromosomes are independently sorted into the bacteriophages. n Cell A's DNA was inserted into Cell B and incorporated into the genome of Cell B.arrow_forwardA medical student is studying a liver biopsy taken from a regenerating liver following a partial hepatectomy. The student sees a dividing cell in which the chromosomes are aligned on a plate. Which of the following best describes the character of the chromosomes in the plate? A. 23 chromosomes with 2N DNA total and with each chromosome having one chromatid B. 23 chromosomes with 4N DNA total and with each chromosome having two chromatids C. 46 chromosomes with 2N DNA total and with each chromosome having one chromatid D. 46 chromosomes with 4N DNA total and each chromosome having two chromatids E. 92 chromosomes with 2N DNA total and with each chromosome having two chromatidsarrow_forward
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