20. A pharmacist adds 10 mL of a 20% (w/v)solution of a drug to 500 mL of D5W forparenteral infusion. What is the percent-age strength of the drug in the infusionsolution?(a) 2% v/v(b) 2% w/v(c) 1.96% w/v(d) 0.39% w/v20. (d) 0.39% w/v

Drug calculation is a important aspect in calculating the dose based on the BMI ,BSA ,age and body…

Answered: 20. A pharmacist adds 10 mL of a 20%…

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter9: Parenteral Medication Labels And Dosage Calculation

Section: Chapter Questions

Problem 7.10P

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18. Esmolol 1.2 g in 500 mL D5W has been ordered at a rate of 100 mcg/kg/min for a client weighting 103.2 kg. Determine the following: a) dosage in mcg/min: b) rate in mL/hr c) Is the dosage administered to the client safe?
1. 2. 3. 4. A physician wants to administer an anesthetic agent at a rate of 5 mg/h by IV infusion. The elimination rate constant is 0.2 h¹ and volume of distribution is 20 L. a. How long will it take to reach a drug concentration of 1 µg/ml? b. How long will it take to reach steady state? c. What loading dose should be recommended if the doctor wants the drug concentration to reach 1.25 µg/ml immediately? What is the concentration of a drug 3 hours after administration of a loading dose of 10 mg and the simultaneous infusion of 2 mg/h? The drug has a half-life of 3 h and a volume of distribution of 10 L? A patient was infused for 12 h with a drug (k= 0.4 h¹; Vd= 15L) at a rate of 5 mg/h. What are the concentrations of the drug at 1, 2, 8, 10, 14, and 16 hours since the start of the infusion? Given the following drug concentrations determine k, V₁, CL and half-life for a drug infused at a rate of 200 mg/h for 8 hours. Time(hr) 1 2 4 8 9 10 14 Drug Concentration(mg/L) 27.50 40 48 50…
When 100 mg of a drug is administered as an IV bolus dose, the plasma concentrations (ug/mL) observed over time (hr) can be described by the following equation: C = 3.6e-0.105t C= 3-6e AUC 36 6 -0.105t 5. Calculate AUC(0-0) 0-105 = 34.28 6. What is the volume of distribution? Dose 100 VD= Co 3-6 7. Calculate the clearance of this drug. CI = KXVD CI = 0•105 x 27-8 %3D %3D Cl=2.9 8. What IV dose would be required to produce an initial plasma concentration of 10 ug/mL?
The peak plasma concentration achieved after the first IV dose of drug X is 25 mg/L. The drug’s half-life is 3.5 hours, and it is administered every 12 hours. What will be the peak plasma concentration at steady state?
A child weighing 22 lbs, has an infection and the doctor orders erythromycin drops 2.0 mLp.o. q6h. The bottle states that the usual dosage is 20.0-40.0 mg/kg/day, and there are35.0 mg per 1.5 mL. Find the min and max dosage per day in mL. Is the order within therecommended dosage?
The biexponential equation for a two compartment model drug is C1,t = 50.0e-1.64t + 20.0e-0.147t. The drug is administered as a rapid IV bolus at t = 0. After 2.00 hours how many mg/l will the drug concentration in the central compartment be.
The initial plasma concentration of a drug given iv at 8:00am is 210 mg/ml. If the half life of the drug is 6 hours, what will the plasma concentration be at 7:00pm that same day?
A 100 ml vial of alteplase, a thrombolytic drug, contains 100 mg of drug equivalent to 58,000,000 international units to be administered via intravenous infusion. Determine the units administered to a patient who weighs 172 lb at a dose of 0.9 mg/kg and the volume of injection to use. 43,100,200 units: 78.60 mL 50,810,000 units: 75.50 mL O45,500,700 units: 73.80 mL 40,808,800 units: 70.40 mL
After oral administration of single 100 mg capsule of an antihypertensive drug to a normal volunteer, the total calculated AUC was 20 mg.hr/L. After intravenous bolus administration of 20 mg, the AUC was 10 mg.hr/L. Calculate the absolute bioavailability of the drug from the tablet applied orally. (10. SLAYT) A) 60% B) 20% C) 40% D) 50% E) 75% What sould be the minimum solubility of an active substance (its molecular weight:500) in the dissolution media to be chosen in order to ensure the sink condition in the paddle method by using a 1 liter volume of beaker of a tablet (its dose strength is 100 mg and tablet weight is 200 mg? (4. SLAYT) 1 mg/ml 200 mg/ml 20 mg/ml 5 mg/ ml 10 mg/ ml
An IV infusion is to contain 40 mEq of potassium ion and 10 mEq of sodium ion in 500 mL of D5W.Using a 20% w/v potassium chloride injection (MW 74.5, valence of 1) and 0.45% sodium chlorideinjection (MW 58.5, valence of 1), how many milliliters of each should be added to the 500mL bag ofD5W to supply the required ions?
6, If Mr. Strong is admitted to the hospital and administered Buprenex, how much will you draw up in the syringe for a 0.6-mg dose? How many milliliters (mL) will be needed per day if the dosage range is 0.3 to 0.6 mg every 6 hours? (Buprenex 0.3 mg/mL.) Please show your calculations. nhohia Use the Internet to

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20. A pharmacist adds 10 mL of a 20% (w/v) solution of a drug to 500 mL of D5W for parenteral infusion. What is the percent- age strength of the drug in the infusion solution? (a) 2% v/v (b) 2% w/v (c) 1.96% w/v (d) 0.39% w/v 20. (d) 0.39% w/v