Answered: 4. What is the intermediate of the…

4. What is the intermediate of the following reaction sequence? 1. O3 Proline ? 2. (CH3)2S (Aldol condensation) (Ozonolysis) A) B) н он OH D) H3CS OH OH H O=

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter23: Addition To A Carbonyl

Section: Chapter Questions

Problem 1E

See similar textbooks

Related questions

Q: 12) Write the product of each step in the following reaction sequence. 1) НОСН-CH,OH, Н,О* 2) LİAIH4…

A: In organic chemistry, inter conversion of organic molecule takes place from one form to another form…

Q: CH H' TH. Na OH CH3

A: The reaction given is aldol reaction.

Q: 6. Draw out the mechanism of the final step(s) of each reaction scheme (i.e., mechanism that starts…

A: The explanation is given below-

Q: Help

A: In aldol condensation, the base abstract the proton from the alpha carbon, the enolate carbon then…

Q: 5. Give the reagents needed for each step in this synthesis. ОН LCECH CECH ON

A: Given,

Q: 48. Percentage yied of Elimination Product I.CH3CHBRCH2CH2CH3 + CH3S/DMSO → II.CH3CHBrCH2CH2CH3 +…

A: Here we have to choose correct option about percentage of yield of above reactions-

Q: A key step in the synthesis of donepezil is a directed aldol reaction that forms α,β- unsaturated…

Q: CH3 NaOH CH3-CH-C-H

Q: D Fill in the reagents to complete the Synthetic and draw the final product EŁOH 30, 2. 3.

A: These reactions are studied in the enolate chemistry, Firstly base will abstract the proton to…

Q: 1. НCN, acid 2. LIAIH4, dry Et,0 H. final product NH2 H* Br он H. internal aldol condensation

A: The solution of the question is given below:

Q: 4. Give synthesis O H3CN- H3CH₂C -NH₂

Q: Identify the type of reaction. A. Clemmensen Reduction B. Cannizzaro Reaction C. Aldol Condensation…

A: Hh

Q: for the following, 1) which bond first breaks with retrosynthesis (ex C6-C7). 2) what product is…

Q: Part 2 out of 2 Formation of the product: Y OH CHO CH3 draw structure ... Draw the major…

A: Part 2 We have to draw the unknown structure and also identify the reagents Y and Z.

Q: Write a plausible reaction sequence of 4 steps starting from A, B, C, or D. You may use any…

Q: 26. Which of the following is an important intermediate of the reaction sequence shown in the box?…

A: ->gilmann reagent ((CH3)2CuLi) give Michael addition reaction when reacts with alpha-beta…

Q: What are the product of the attached reaction?

A: NBS (N-bromosuccinimide) is used as a reagent for allylic bromination of the given compound. Allylic…

Q: 36) (1) Complete the following reactions with appropriate products. acylation nitration isoprCOCI…

A: Step 1 : Fridel craft acylation. Step 2 : Nitration. Step 3 : Wittig reaction. Step 4 :…

Q: CO2ME Me- Me CO2ME hv 12 Ме., PhCI Me Me 110°С, 87% Me Ме Ме

Q: 1) NaOEt Me OEt 2) H30* Could you show the mechanism please, also how do you know which alpha…

A: Given : We have to write the product for the given reaction.

Q: intermediate product NH, 1 2 6 10 8 9 -1

A: The sequence of reaction to reagent 10 and the role of reagent are express below Reagent 1 :…

Q: 25°C HO. HO. Na* OH (aq) OH (aq) 25°C 85°C aldol

A: Answer:- This question is answered by using the simple concept of chemical reaction of self Claisen…

Q: Draw the product of the reaction shown below at physiological pH (pH = 7.4). Ignore inorganic…

Q: What is TRUE about the reaction below? Select one: O a. The reaction has the same rate when the base…

A: Organic reactions are those in which organic reactant react to form organic products.

Q: 27. (10) Write a reasonable mechanism for the following transformation. H₂SO4 OH OH 28 + Predict the…

A: Here we have to write the mechanism of the following given reactions. Here the first reaction is…

Q: Propose the reaction mechanism of the following reaction. 32. Propose the reaction mechanism of the…

A: In presence of heat first ring opening occurs then (4+2) cycloaddition reaction occurs.

Q: 1) 2 possible enolates can form when using (CH3)3CO– as the base to form the enolate of the ketone…

A: the tert butoxide ion is considered a bulky base 2t abstracs less hindrance 2°∝H that leads to less…

Q: HO2C CH2N2 H H Me., Me Et20 90 & (4 steps) Me., Me Me Me

A: Diazomethane (CH2N2) reacts with carboxylic acid to form methyl ester. CH2N2 abstracts proton from…

Q: Determine the product and name of the rxn HO 1. Аc-0, AcO-Na+ (A) 2. Н20 Ac20= acetic anhydride…

Q: Compound (a) is an intermediate in the mechanism showing the formation of acetal (f). Which…

A: The reaction mechanism of formation of acetal via intermolecular reaction results in formation of a…

Q: 9. Draw the product of this reaction sequence. No mechanism is required KMNO4 Cl2 H* HO, heat FeCl3…

A: When alkyl substituted benzene, ethyl benzene, is treated with potassium permanganate in presence of…

Q: Q10 Using an aldol or crossed aldol condensation, suggest a synthesis of the following compounds: me…

A: In organic chemistry, an aldol condensation is a condensation reaction in which an enol or enolate…

Q: 1. Draw the structure of the intermediate products in the following reactions: (C,H),P-CH CH3 AICI,…

Q: What is the structure of an intermediate in the methyl shift rearrangement reaction shown in the…

Q: 4. Describe in table format the following criteria for S,' reactions: (a) strength of nucleophile;…

A: Following are the explanation for SN1 reaction according to given parameters. Dear student, since…

Q: Consider the reaction sequence shown in the box. The intermediate of the reaction sequence is an…

A: A Gilman reagent is a lithium and copper (diorganocopper) reagent compound, R2CuLi.

Q: 2) Formulate the mechanism with all intermediates for the formation reaction of benzyl ether from…

A: Alcohols are organic compounds that are characterized by the presence of a hydroxyl group (-OH)…

Q: Me Ме МeONa/ MeOН /12

A: Reactions - When a methyl ketones reacting with a base MeONa or Meoh and halogen used…

Q: Draw the substitution product(s) of the following reaction and show the mechanism by drawing the…

A: The products are

Q: tu II it 1ONIlal 1epot. OH ОН О H. A For the "crossed" aldol reaction that lead to product C, did…

A: Aldol condensation is a very important reaction in organic chemistry. This is a condensation between…

Q: Draw the intermediate compound after each step of this multistep synthesis. The intermediate…

A: The intermediate compound in the reaction has to be given,

Q: What product is formed after 2 reactions (dilute acid then HIO4, H2SO4)?

A: In this question, we will give two products one is after diluted acid and another is after HIO4 /…

Q: 2. (a) What is the major enolate formed in each reaction? Justify your prediction : LDA, THF -78 °C…

A: Carbonyl compound having acidic alpha hydrogen, reacts with base to form enolate ion. The enolate…

Q: piligonoal o lo oo i gutwollot 6A. Draw all of the possible aldol addition and condensation products…

Q: CH, 0 NaOH CH3-CH-C-H

Q: 2) What two organic starting materials are required to produce cinnamaldehyde (PHCH=CHCHO) via a…

A: Cross aldol condensation: In this reaction, a condensation of aldehyde or ketone takes place in…

Q: ОН H3O 2 CH3-C-H A В Aldol addition A Aldol condensation product product

A: First we will draw aldol addition product, then it will undergo dehydration to form condensation…

Concept explainers

Alkanes and Cycloalkanes

Alkanes are saturated organic compounds which are made up of C and H atoms. Alkanes have the general formula of CnH2n+2. Alkane contains sp3 hybridized carbon atoms with four sigmas (σ) bonds & every hydrogen atom is connected with one of the carbon atoms. The size of the alkane could be determined by the number of carbon atoms located in it.

Question

4. What is the intermediate of the following
reaction sequence?
1. O3
Proline
2. (CH3)2S
(Aldol condensation)
(Ozonolysis)
A)
н он
OH
B)
C)
D)
H3CS OH
OH
H.

Expert Solution

Step 1

Trending now

This is a popular solution!

Step by step

Solved in 2 steps with 2 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

1). Fill in the missing intermediates and product in the following mult-step synthesis:
Which of the following does not support a nucleophilic attack of a covalent catalysis? a. Hydroxyl b. Sulfhydryl c. Imidazole d. Amino e. Methyl
What is the strongest nucleophile, NH3, CH4, CH3O-, or H2O?
6. For the following reaction, draw all of the synthetic intermediates that are formed in each step, including the final product. 1. H2SO4 2. mCPBA 3. MgBr-CH2CH3 4. H20 HO.
For the following reaction step, indicate which pattern of arrOw pushing it represents. :O: CI: H. proton transfer loss of leaving group C) nucleophilic attack rearrangement
please help me to make synthesis of chrysin (5,7-dihydroxyflavone) in 4 or more steps and start for any compound these photo of chrysin compund
D) 2) What two organic starting materials are required to produce cinnamaldehyde (PHCH=CHCHO) via a crossed aldol condensation followed by dehydration? A) PHCH3 and CH3CHO B) PHCHO and CH3CH2CHO C) PHCHO and CH3CH2OH D) PHCHO and CH3CHO uart "nolizable ketone to its enolate
9. Draw the complete mechanism of the following haloform reaction. 1. NaOH Cl, (excess) HO 2. H3O* OH
Provide the synthetic route for the following reaction? (CH3)2CHCH2Br ----> (CH3)2CHCH2CH2CH2NH2
12) Write the product of each step in the following reaction sequence. 1) НОСН-CH,OH, Н,О* 2) LİAIH4 3) excess MeMgBr LOCH2CH3 4) H3O*
R The mechanism involves the following 5 steps: haloketone with base to yield a ring-contracted product. 1. Abstraction of a proton to form enolate anion 1; 2. Formation of a cyclopropanone intermediate 2 with expulsion of chloride ion; 3. Addition of hydroxide ion to form tetrahedral intermediate 3; 4. Collapse of the tetrahedral intermediate and breakage of the three-membered ring to form carbanion intermediate 4; 5. Proton transfer to form the rearranged carboxylic acid. For the following reaction, draw the reaction out on paper and then draw the structure of cyclopropanone intermediate 2 in the window. CO₂H CI 8 5 base . You do not have to consider stereochemistry. . You do not have to explicitly draw H atoms. . Do not include lone pairs in your answer. They will not be considered in the grading. . Do not include counter-ions, e.g., Na, I, in your answer. ***** O. Sn [F
What would be the missing steps and intermediates for the following reaction?