piligonoal o lo oo i gutwollot 6A. Draw all of the possible aldol addition and condensation products from the following reaction (you may ignore stereochemistry of aldol products but not condensation): NaOH OMe ? H3C CH3 ÓMe

piligonoal o lo oo i gutwollot 6A. Draw all of the possible aldol addition and condensation products from the following reaction (you may ignore stereochemistry of aldol products but not condensation): NaOH OMe ? H3C CH3 ÓMe

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter23: Carbonyl Condensation Reactions

Section23.3: Dehydration Of Aldol Products: Synthesis Of Enones

Problem 4P

See similar textbooks

Related questions

Q: Он о OH O Он о Он о H. ÓH II IV V Which of the following molecules is not a possible product when a…

A: Aldol condensation: The alpha hydrogen of carbonyl compounds is acidic in nature and it is removed…

Q: The following is an aldol condensation reaction, involving two different carbonyl compounds, one…

Q: H;C CH3 -CH=CH-C -CH,CH3 -CH=Ċ- -CH3

Q: What starting materials are needed to synthesize each compound using an aldol or similar reaction?

A: The reactant of a product can be determined by the retrosynthetic method. The retrosynthetic method…

Q: Draw the product formed (after dehydration) in the crossed aldol condensation of phenylacetaldehyde…

A: Cross aldol reaction is the reaction between two different aldehyde or ketone compounds. The product…

Q: Propose a mechanism for the aldol condensation of cyclohexanone. Do you expect theequilibrium to…

A: In base-catalyzed aldol condensation, nucleophilic addition of an enolate ion takes place on a…

Q: 8.45 Which of the following compounds undergoes E2 elimination with strong base? For compounds that…

A: Welcome to bartleby ! We have to tell which decalin will undergo alkene

Q: What is the expected product A for the following intramolecular aldol reaction? CH3 O NaOH A H3C H.…

Q: A key step in the synthesis of donepezil is a directed aldol reaction that forms α,β- unsaturated…

Q: 6. How would you synthesize the enone below from a crossed Aldol reaction?

A: We have to synthesis the given enone by cross aldol reaction. Cross aldol reaction involve of two…

Q: ...

Q: What conditions are necessary for a crossed-aldol reaction to occur? NaOH, H20 H. H. 50° C I II O…

A: In this question, we have to find out the correct answer of given problem by the help of the…

Q: 2) Increasing yield in cross Aldol condensation p-methyl benzaldehyde, p-methoxy benzaldehyde,…

A: Aldol condensation is the condensation of two distinct aldehydes or ketones, at least one of which…

Q: 4. Give the crossed aldol product for the following reaction. NaOH (aq) + H. 25 °C

A: The Cross Aldol condensation reaction is a type of organic reaction . In the Reaction two Carbonyl…

Q: . Carefully draw the product of the following aldol condensation/dehydration reaction: КОН ? H20 + 2…

A: This reaction occurs in 3 steps: Step 1: Formation of Nucleophile by one of the molecule. Step 2:…

Q: Dehydration via an E1cb mechanism Michael Reaction Intramolecular Aldol Reaction В KOH / ELOH / heat…

A: We know, Micheal reaction is basically the nucleuphilic addition reaction which is basically 1-4…

Q: into the indicated products. Identify the substrate, reagent(s) and catalyst if any used for each…

Q: What conditions are necessary for a crossed-aldol reaction to occur? NaOH, H2O H. H. 50° C II O…

A: Concept is based on Aldol reaction

Q: Q4- The following molecules can be formed by either:; Enamine Acylation; Aldol Condensation; Claisen…

Q: Aldehydes that do not undergo aldol condensation are I) propanal II) trichloroethanal III)…

A: 1) With Grignard's reagent aldehydes gives organometallic compounds which on hydrolysis gives…

Q: Propose a mechanism, using curved arrows, for the base-catalysed aldol reaction and the subsequent…

Q: 6. The molecules shown below are capable of undergoing either an aldol or Claisen reaction. H O H a)…

A: The detailed solution of the given are provided below in attach image.

Q: Q5 If you took a TLC of an Aldol reaction/condensation what would be the order of the spots on the…

A: Applying concept of polarity of molecules and relationship with Rf value .

Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

A: The reaction taking place is given as,

Q: 5. Which of the following compounds will not undergo Aldol reaction and why? `H `H а. b. CH3 с. d.…

A: If adjacent carbon of carbonyl carbon contain alpha hydrogen (sp3 hybridised) then undergo aldol…

Q: 2. The following reaction will make co-major products, one aldol, and one Claisen, draw both and…

A: There are two possible products for given reaction. 1. Aldol 2. claisen

Q: q. aldol of pentan-3-one with sodium hydroxide in water followed by acid r. caproic acid + methanol…

Q: 23. Show the complete stepwise reaction mechanism for the following Aldol condensation reaction. Use…

A: Carbonyl compounds are the organic compounds containing the C=O group. Ketones and aldehydes belong…

Q: 4. What is the intermediate of the following reaction sequence? 1. O3 Proline ? 2. (CH3)2S (Aldol…

Q: 0-H + HB + B

A: Aldol condensation: An aldol condensation is a type of condensation reaction in organic chemistry in…

Q: What is TRUE about the reaction below? Select one: O a. The reaction has the same rate when the base…

A: Organic reactions are those in which organic reactant react to form organic products.

Q: There are other condensation reactions similar to the aldol and Claisen condensations: a. The Perkin…

A: The Perkin condensation is the condensation of an aromatic aldehyde and acetic anhydride. It is…

Q: d. Predict the aldol product when the following aldehyde is allowed to react under the following…

A: Reaction 1 : Aldol condensation. Reaction 2 : Michael addition.

Q: Cinnamaldehyde may be synthesized through aldol condensation reaction of two aldehydes Q and R as…

Q: Robinson Annulation Practice Problems: Fill in the missing intermediates, products or starting…

Q: OH OH Ni 25°C heat E2 H, H. aldol 1) LIAIH, 2) H,O*

A: In aldol condensation reaction, two carbonyl compounds (aldehydes or ketones) react with each other…

Q: 3. The Aldol condensation reaction shown below can be properly called a crossed aldol condensation.…

A: Note: Since you have asked multiple questions, we will solve the first question for you. If you want…

Q: 1. Show the method to carry out each transformation: two-step method using a Grignard reagent. CH3…

Q: The Robinson annulation reaction involves Michael addition and aldol condensation and it is a ring…

Q: Which of the following pairs will give two cross-aldol products? and H. (H3C)3C H. and H. TH. CHO…

Q: CH CH, Draw the structure of the major organic product of the following reaction. Predict whether…

A: The given reaction is an aldol condensation where the reaction proceeds in the following three…

Q: CH, KOH CH二CH NO2

Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

Q: Which of the following molecules is not able to undergo an aldol self-condensation? CH₂ A H₂C 00.0 어…

A: we have to select the molecule which cannot participate in aldol self condensation

Q: NaOH КОН A H20 EtO H20 NaOEt NaH B EtO H. HOET CląC Cl3 OEt THE +

A: Since you have posted a question with multiple sub-parts, we will solve first three subpartsfor you.…

Q: e aldol condensation is complete once the aldol product above undergoes an elimination upon heating.…

A: Please find below the reaction with missing bonds, and curved arrows.

Q: Aldol product Donor Acceptor сно OH 2. но co,C2H5 CHO CHO A B D co,C2H5 F CHO co,C2HS

Q: 4.Predict the products of the following aldol condensations. Indicate the product before and after…

A: Aldol condensation: The alpha hydrogen of carbonyl compounds is acidic in nature and it is removed…

Q: 3-Methylbutanal undergoes an aldol reaction to form 3-hydroxy-2-isopropyl-5-methylhexanal as shown.…

Q: 4.Which is the most thermodynamically stable product of the following aldol condensation reaction?…

A: I would Say E,E as Phenyl Group is bulky so it will prefer to go on E- configuration

Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

taneon lo robio i guiwollol o n
6A. Draw all of the possible aldol addition and condensation products from the following
reaction (you may ignore stereochemistry of aldol products but not condensation):
NaOH
OMe
?
H3C
CH3
H
OMe
Jobong oryloby vithob
plam

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps with 2 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction. CH3 CH3 H dilute NaOH 95% aq. ethanol, 0-5⁰ You do not have to consider stereochemistry. • If no reaction occurs, draw the organic starting material. O-Sn [F ? ChemDoodleⓇ
@GMU 73765 What is the expected product A for the following intramolecular aldol reaction? O CH3 O NaOH A H3C EtOH H
Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction. CH3 CH3- CH3 H dilute aqueous NaOH 0-5⁰ You do not have to consider stereochemistry. • If no reaction occurs, draw the organic starting material. Sn [F ? ChemDoodleⓇ
Q6. Propose a mechanism, using curved arrows, for the base-catalysed aldol reaction and the subsequent dehydration between furfural and cydahexanene КОН H
The reaction below is a base-catalyzed aldol reaction. O || CH₂-C-H CH3-C-H Ethanal (Acetaldehyde) H I CH3-C-H Ethanal (Acetaldehyde) NaOH Draw curved arrows to show the movement of electrons in the step of the mechanism shown below. Arrow-pushing Instructions AC⇒x= :O: || :CH₂-C-H OH Bl CH3-CH—CH2-CH -CH₂-1-1 a 3-Hydroxybutanal (B-hydroxyaldehyde; formed as a racemic mixture) :0: :0: || CH3—CH—CH2-C-H A tetrahedral carbonyl addition intermediate X
Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction. O ⇐ H dilute NaOH 95% aq. ethanol, 0-5° • You do not have to consider stereochemistry. •If no reaction occurs, draw the organic starting material. + HO CH3 On t ?
What is the reactant that would give the following Aldol Condensation product? 01 0 | 0 ||| O IV OV H H تبار نہید لبد بد مبد IV :O: ة :0: :0: :O:
18en the folbwng sequence of reac ond what wo structure of compound AT D (CH,,CULI 2) H,0 HN-CH, H,0 Select one 2.Wnchufthfollewine.comectly represert eet the stepm the rechnsnetamad altalcardensation react
Draw the mechanism of the following reaction. Do the cyclization steps follow Baldwin's rules? (Hint: The mechanism starts with hydrolysis of the acetal to aldehyde) OEt OEt 2M HCI
The aldol addition product of the following reaction is мен (2 mol) A OH A D B кон, но 6-8 °С OH во OH с сно ОН D CHO
Identify a type of reaction that can be used to prepare the compound below without the need for any further reactions. MeO O Conjugate addition O enolate alkylation O Claisen condensation O aldol reaction Submit Answ
Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction. CH3 CH3 CH3 H dilute aqueous NaOH 0-5° • You do not have to consider stereochemistry. • If no reaction occurs, draw the organic starting material. {n [t ? ChemDoodle