The conversion of pyruvate into acetyl CoA consists of three steps. Identify these three steps and order them from first to last. decarboxylation oxidation acetyl transfer First step Last step Answer Bank reduction condensation
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- Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.Identify a pathway for utilization of the four carbons of acetoacetate in cholesterol biosynthesis. Carry your pathway as far as the rate-determining reaction in cholesterol biosynthesis. Drag the appropriate labels to their respective targets. succinyl-CoA succinate acetyl-CoA CoA-SH acetoacetyl-CoA HMG-CoA 2NADP 2NADPH+ 2H acetoacetate K UHL return to a mevalonate + CoA-SHPart A Identify each of the following metabolic pathways. Drag the appropriate labels to their respective targets. Reset Help the conversion of fatty acids to 2-carbon units of acetyl CoA ketogenesis the conversion of an amino acid to an a-keto transamination acid the combination of 2-carbon units of acetyl COA to form fatty acids oxidative deamination the removal of an amino group as NH4+ from B oxidation glutamate to yield a-ketoglutarate lipogenesis the production of ketone bodies
- Which reaction below corresponds with substrate level phosphorylation? Fructose-1,6-bisphosphoglycerate >>>> G3P Pyruvate >>>> Acetyl-CoA Glucose >>>> Glucose-6-phosphate 1,3-bisphosphoglycerate >>>> 3-phosphoglycerate >>>> pyruvate Acetyl + Oxaloacetate >>>> CitrateThe conversion of pyruvate to Acetyl-CoA involves an oxidative decarboxylation. Correct the path of the electrons through this mechanism: Pyruvate -> NAD -> lipoamide -> FAD -> TPPC-CH2 + H* CO, + CH,-C-S-COA S-COA Malonyl-CoA Acetyl-CoA Hydrolase Transferase Lyase Ligase
- What is the rate-limiting step in the synthesis of acetyl CoA? oxidation regeneration of lipoamide decarboxylation transfer to lipoamide transfer to CoAWhich of the following is NOT part of the multi-enzyme complex of fatty acid synthase? O enoyl-ACP reductase O acetyl CoA carboxylase O 3-hydroxybutyrylACP-dehydratese O B-ketoacyl-ACP reductaseWhat is the final reaction in the final round of fatty acid synthase? Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP Reductase
- The large amount of energy used during aerobic exercise(e.g., running) requires large amounts of oxaloacetate.Explain why acetyl-CoA cannot be used to produceoxaloacetate in this circumstance. What is the sourceof oxaloacetate molecules during aerobic activity?All of the following are accurate contrasts for beta oxidation vs fatty acid synthesis except which of the following statements? Group of answer choices The hydroxylacyl group differs in stereochemistry between beta oxidation and biosynthesis CoA is the acyl carrier group in beta oxidation, acyl carrier protein is the carrier in biosynthesis The carbon unit resulting from beta oxidation is acetyl-CoA, the carbon unit for biosynthesis is malonyl-CoA FAD is an electron acceptor in beta oxidation, NADP+ is the electron acceptor in biosynthesisWhich of the following is most helpful in ensuring that wasteful (unproductive) hydrolysis of acetyl CoA does not occur in the reaction catalyzed by citrate synthase? Group of answer choices Citrate synthase is a tetramer Induced fit ensures oxaloacetate binds before acetyl CoA 3 molecules of oxaloacetate bind for every 1 molecule of acetyl CoA Citrate inhibits the reaction Which of the following catalyzes a step that does NOT produce CO2? Group of answer choices alpha-ketoglutarate dehydrogenase complex malate dehydrogenase pyruvate dehydrogenase complex isocitrate dehydrogenase Citrate synthase is regulated by... Group of answer choices Concentrations of substrate and products Fructose-2,6-Bisphosphate Covalent modification Allosteric regulation by the levels of NADDH