Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781259709227
Author: Marjorie Kelly Cowan Professor, Heidi Smith
Publisher: McGraw-Hill Education
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Chapter 10, Problem 4Q
Summary Introduction
Introduction:
Antimicrobial strategy revolves around the necessary
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Technically speaking, true antibiotics are drugs…
A. Produced naturally by microbes
B. Taken orally, not injected.
C. Used to treat any microbial infection
D. Used to treat any bacterial disease.
We have many antimicrobial drugs to treat bacterial infections, but very few for viruses. Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?
Which of the following drugs inhibits protein synthesis through binding to ribosomal 30S subunit:
O a. Linezolid
O b. Amikacin
O c. Ciprofloxacin
O d. Azithromycin
Chapter 10 Solutions
Microbiology Fundamentals: A Clinical Approach
Ch. 10.1 - State the main goal of antimicrobial treatment.Ch. 10.1 - Identify the sources for the most commonly used...Ch. 10.1 - Describe two methods for testing antimicrobial...Ch. 10.1 - Prob. 4AYPCh. 10.1 - NCLEX PREP 1. An RN is caring for a 26-year-old...Ch. 10.2 - Explain the concept of selective toxicity.Ch. 10.2 - List the five major targets of antimicrobial...Ch. 10.2 - Prob. 7AYPCh. 10.2 - Distinguish between broad-spectrum and...Ch. 10.2 - Prob. 9AYP
Ch. 10.2 - Explain the mode of action of penicillinases and...Ch. 10.2 - Identify two antimicrobials that act by inhibiting...Ch. 10.2 - Prob. 12AYPCh. 10.2 - Identify one example of a fluoroquinolone.Ch. 10.2 - Describe the mode of action of drugs that target...Ch. 10.2 - Prob. 15AYPCh. 10.2 - Prob. 16AYPCh. 10.2 - Explain why antiprotozoal and antihelminthic drugs...Ch. 10.2 - List the three major targets of action of...Ch. 10.2 - Prob. 2NPCh. 10.3 - Discuss two main ways that microbes acquire...Ch. 10.3 - List five cellular or structural mechanisms that...Ch. 10.3 - Prob. 21AYPCh. 10.3 - Prob. 3NPCh. 10.3 - Prob. 1MMCh. 10.4 - Distinguish between drug toxicity and allergic...Ch. 10.4 - Prob. 23AYPCh. 10.4 - Prob. 4NPCh. 10.4 - Prob. 5NPCh. 10 - Microbial resistance to drugs is acquired through...Ch. 10 - Prob. 2QCh. 10 - Prob. 3QCh. 10 - Prob. 4QCh. 10 - Why does the penicillin group of antibiotics have...Ch. 10 - Prob. 6QCh. 10 - Prob. 7QCh. 10 - Conduct research to find out why drugs blocking...Ch. 10 - Prob. 9QCh. 10 - Prob. 10QCh. 10 - You take a sample from a growth-free portion of...Ch. 10 - Prob. 12QCh. 10 - Treating malarial infections is theoretically...Ch. 10 - Can you think of a situation in which it would be...Ch. 10 - Prob. 15QCh. 10 - Prob. 16QCh. 10 - Prob. 17QCh. 10 - Prob. 18QCh. 10 - An antimicrobial drug with a _______ therapeutic...Ch. 10 - Prob. 20QCh. 10 - Prob. 21QCh. 10 - Prob. 1VC
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- 1.) Which of the following are criteria for antibiotics? ( Select all that apple) A. Kill viruses B. Chemical substances produced by a microscope C. Effective in small doses D. Stops the growth or kills other microorganisms. 2) which antibiotic inhibits protein synthesis? ( select all that apply) A. Gentamicin B. Amoxicillin C. Erythromycin D. Tetracyclinearrow_forwardWhat is the specific mode of action and the target organisms of each of the three antibiotics used in the exercise (isolation of E. coli bacteriophage)?a. Ampicillin:b. Polymyxin:c. Streptomycin:arrow_forwardThe first step for directly linking a microbe to a specific disease according to Koch's postulates is to A.isolate microbes from the blood of healthy animals. B. culture the blood or other body fluid from a diseased animal using nutrient medium. C. inject a sample of blood or other body fluid from a diseased animal into a healthy animal. D. obtain a sample of blood or other body fluid from a diseased animal.arrow_forward
- what is the mechanism of action for penicillins? a. injury to plasma membrane b. inbibition of protein synthesis c. inhibition of cell wall synhesis d. inhibition of nucleic acid synthesis e. none of the above describes the mechanism of action for penicillinsarrow_forwardIdentify examples of cell-wall antibiotics that are not beta-lactam drugs.arrow_forwardExplain why drugs that effect bacterial ribosomes can be safely used in treating people.arrow_forward
- Drugs are often given to patients before going into surgery, to dentalpatients with heart disease, or to healthy family members exposed tocontagious infections.a. What word would you use to describe this use of drugs?b. What is the purpose of this form of treatment?c. Explain some potential undesired effects of this form of therapy.d. Define probiotics and list some ways they are used.arrow_forwardIntroduction: There’s quite a bit of interest around repurposing extant drugs to treat infections by targeting host pathways that pathogens rely on. Here are a few potential drugs: 1) A drug that inhibits endocytosis, but not phagocytosis. 2) A drug that inhibits degradation of cytoplasmic proteins into smaller peptides, preventing their cycling back into amino acids. 3) A drug used to treat porphyria that reduces the reactivity of heme. 4) A drug that depletes glutathione, a chemical which protects red blood cells against the reactivity of heme. 5) A drug that reduces expression of the ACE-2 protein. Question: Pick a drug and an infection that the drug is likely to be good at treating, or pick an infection and a drug that would most likely make the infection substantially worse. Which drug and pathogen did you pick? Do you think it’ll make it better or worse?arrow_forwardMost antiviral drugs: a) damage the cell wall b) are nucleoside analogs c) are enzymes inhibitors d) prevent viruses from entering cells e) damage the plasma membranearrow_forward
- Discuss why it is important for us to conduct research at the basic level of physiology in order to better understand what makes Mycobacteria latent or grow during an infection so that we can design new and/or better treatment modalities.arrow_forwardSubstances that are naturally produced by certain microorganisms that can either inhibit or destroy other microorganisms are called: a)semisynthetic drugs b) narrow-spectrum drugs c) antibiotics d) synthetic drugsarrow_forwardGive two reasons why bacteria are becoming more and more resistant to antibiotics.arrow_forward
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