Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 19, Problem 2P
Interpretation Introduction
(a)
Interpretation:
The effect of increase in the concentration of
Concept Introduction:
Enzyme catalyzes
Interpretation Introduction
(b)
Interpretation:
The effect of increase in the concentration of ATP on the TCA cycle needs to be explained.
Concept Introduction:
Enzyme catalyzes chemical reaction in cells is called Tricarboxylic acid cycle (TCA). It is also known as Krebs cycle and citric acid cycle. The
Interpretation Introduction
(c)
Interpretation:
The effect of increase in the concentration of isocitrate on the TCA cycle needs to be explained.
Concept Introduction:
Enzyme catalyzes chemical reaction in cells is called Tricarboxylic acid cycle (TCA). It is also known as Krebs cycle and citric acid cycle. The
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Students have asked these similar questions
. Briefly describe the biological rationale for cach of the following allosteric
phenomena: (a) activation of pyruvate carboxylase by acetyl-CoA; (b) acti-
vation of pyruvate dehydrogenase kinase by NADH; (c) inhibition of isoci-
trate dehydrogenase by NADH; (d) activation of isocitrate dehydrogenase by
ADP; (e) inhibition of a-ketoglutarate dehydrogenase by succinyl-CoA;
(f) activation of pyruvate dehydrogenase phosphatase by Ca*.
From the complete oxidation of glucose (glucose → 6CO2), how many total NADH electron carriers are produced and how many total nucleotide triphosphates are yielded (be sure to deduct payback) as part of substrate level phosphorylation?
Match the name of the process with its description
Electron transport chain
oxidation of pyruvate
chemiosmotic phosphorylation
citric acid cycle
1.
The 2-carbon acetyl group separates from coenzyme A and attaches to a four carbon molecule called oxaloacetate, forming the 6-carbon molecule called citrate. In a series of enzyme-catalyzed steps, the citrate loses 8 high-energy electrons to NAD+ and FAD. In addition, ADP is phosphorylated (changed to ATP) as part of step three. Carbons leave as carbon dioxide in steps 2 and 3. This leaves a 4-carbon molecule, which eventually combines with another Acetyl CoA to form citrate and the cycle begins again.
2.
Pyruvate moves into the mitochondrion and two electrons are removed from pyruvate and transferred to NAD+. One of the carbon atoms in pyruvate leaves as a molecule of carbon dioxide. The remaining 2-carbon piece becomes attached to Coenzyme A.
3.
Protons concentrated in the…
Chapter 19 Solutions
Biochemistry
Ch. 19 - Radiolabeling with 14C-Glutamate Describe the...Ch. 19 - Prob. 2PCh. 19 - Assessing the Effect of Active-Site...Ch. 19 - Understanding the Mechanism of the -Ketoglutarate...Ch. 19 - Understanding the Action of Fluoroacetate on the...Ch. 19 - Prob. 6PCh. 19 - Prob. 7PCh. 19 - Prob. 8PCh. 19 - Prob. 9PCh. 19 - Prob. 10P
Ch. 19 - Prob. 11PCh. 19 - Prob. 12PCh. 19 - Prob. 13PCh. 19 - Prob. 14PCh. 19 - Prob. 15PCh. 19 - Prob. 16PCh. 19 - Understanding the Oxidation of Glucose and Its...Ch. 19 - Prob. 18PCh. 19 - Prob. 19PCh. 19 - Prob. 20PCh. 19 - Complete oxidation of a 16-carbon fatty acid can...Ch. 19 - Study Figure 19.18 and decide which of the...Ch. 19 - Prob. 23P
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