Chapter 2, Problem 20RQ

Summary Introduction

To examine: Whether the statement “Some individuals have an increased need for folate due to the gene variant 5,10-methylenetetrahydrofolate reductase that blocks the absorption of folate from food” is true or false.

Introduction: Folic acid is an essential vitamin that is absorbed from food. It is involved in various cellular processes. 5,10-methylenetetrahydrofolate reductase (MTHFR) is an enzyme that functions to convert folate into active forms that can be used as substrates for the synthesis of amino acids, proteins, and phospholipids.