Lehninger Principles of Biochemistry
7th Edition
ISBN: 9781464126116
Author: David L. Nelson, Michael M. Cox
Publisher: W. H. Freeman
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Chapter 21, Problem 18P
Summary Introduction
To draw: The mechanism for each of the three reactions involved in the pathway for synthesis of mevalonate from acetyl CoA.
Introduction:
The mevalonate pathway is also known as HMG-CoA reductase pathway. It begins with acetyl CoA and produces isopentyl pyrophosphate and dimethylallyl pyrophosphate. Statin which is provided for lowering the cholesterol level in the body targets the mevalonate pathway to decrease the cholesterol level.
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