Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 23.6, Problem 1BC
Summary Introduction
To analyze:
The importance of RNA polymerase II in eukaryotes and the effect of amanitin toxin have on human cells.
Introduction:
RNA polymerase found in the nucleus of eukaryotic cells usually. It is a multiprotein complex. It catalyzes the transcription of DNA to produce precursors of mRNA. The RNA polymerase II includes RNAP II and Pol II.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
M13 is a filamentous phage that infects the bacterium Escherichia coli. Infection with M13 is
not lethal. However, the infection causes turbid plaques in E. coli because infected bacteria
grow slower than the surrounding uninfected bacteria. This phage has been engineered to act
as a vector system. Explain how the amplification of gene of interest works in this phage with
illustration.
Figure 5 shows the lac operon structure in Escherichia coli.
a) Name structures P, Q and R.
b) Name substance S.
c) What is the enzyme encoded by gene I. Give its function.
d) What will happen if substance S is absent in the medium?
The structure of a prodrug used for treating people with HIV virus (human immunodeficiency virus) and AIDS is shown below. This molecule is a precursor of a protease inhibitor that competitively inhibits HIV protease due to its resemblance to the proteolytic site of the enzyme. Which process in the viral life cycle does this inhibitor target directly ?
Group of answer choices
a. viral protein processing for making new viruses
b. viral mRNA synthesis
c. viral DNA integration into the host cell DNA
d. viral DNA synthesis
Chapter 23 Solutions
Principles of Biology
Ch. 23.1 - Prob. 1TYKCh. 23.1 - Prob. 2TYKCh. 23.2 - Prob. 1TYKCh. 23.2 - Prob. 2TYKCh. 23.3 - Prob. 1CCCh. 23.3 - Prob. 1TYKCh. 23.3 - What essential role did early alphaproteobacteria...Ch. 23.4 - Prob. 1CCCh. 23.4 - Which structure is associated with motility in one...Ch. 23.5 - In which of the hosts does sexual mating of P....
Ch. 23.5 - Prob. 1TYKCh. 23.6 - Prob. 1CCCh. 23.6 - Prob. 2CCCh. 23.6 - Prob. 1BCCh. 23.6 - Prob. 1TYKCh. 23.7 - Prob. 1TYKCh. 23 - Prob. 1TYCh. 23 - Prob. 2TYCh. 23 - Prob. 3TYCh. 23 - Prob. 4TYCh. 23 - Prob. 5TYCh. 23 - The protists most closely related to the fungal,...Ch. 23 - Prob. 7TYCh. 23 - Prob. 8TYCh. 23 - People use bacteria, protists, or fungi to: make...Ch. 23 - Prob. 1CCQCh. 23 - Prob. 2CCQCh. 23 - Prob. 3CCQCh. 23 - Prob. 1CBQCh. 23 - Prob. 2CBQ
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Name a nucleoside analog. Explain how that nucleoside analog works. Which viruses are effectively treated by that nucleoside analog?arrow_forwardYou were able to obtain the RNA of the influenza virus. If you injected this into a susceptible host cell could this RNA alone cause a lytic infection? Please explain why or why not with proper reasoning.arrow_forwardIn the treatment of acquired immunodeficiency syndrome (AIDS), a possible mode of therapy is to inhibit the reverse transcriptase (RT) of the human immunodeficiency virus (HIV), whcih is required for the retrovirus to be propogated by RNA-directed DNA synthesis. In the figure below, one of the substrates for RT is thymidine; and two drugs, AZT and HBY097 are known to inhibit HIV RT> (a) Thymidine; (b) AZT; (c) HBY097 Look at the structures and predict the type of inhibition (i.e. competitive or non-competitive) likely to be shown by each drug. By using knowledge on enzyme, plan an experiment that would enable you to confirm the type of inhibition by investigating enzyme kinetics and explain how you would interpret the results.Remarks: Not more than 250 words.arrow_forward
- Imagine that a researcher discovers a new type of virus. This virus contains single‑stranded RNA with "negative" sense. Consider the image. Which statement is true regarding this virus? According to the Baltimore system, this virus would be classified as a type V virus. Based on the presence of single‑stranded RNA, this virus is likely similar to HIV. According to the Baltimore system, this virus would be classified as a type IV virus. This virus must use reverse transcriptase to produce mRNA.arrow_forwardThe lac operon has 4 genes, I, Z, Y and A. For each scenario, tell me the result of the mutation, what would happen if this mutant was in the presence of lactose and why. A) Lac I is mutated/not functional - B) Lac Y is mutated/not functional -arrow_forwardIf a viral host cell has a mutation that interferes with the addition of carbohydrates to proteins (glycoproteins) during processing in the Golgi apparatus, which of the following processes is most likely to occur? O A. Viruses released by that host cell would have a decreased ability to infect cells than the virus that originally infected the cell. B. The virus-encoded protease would be unable to cleave large viral proteins into smaller, functional polypeptides. OC. The virus would be unable to replicate within the host cell. D. Viruses released by that cell are novel and would result in infections with higher mortality rates.arrow_forward
- Why are bacterial DNA gyrase and topoisomerase good targets for antimicrobial drugs? These enzymes are not necessary for DNA replication. These enzymes are involved in energy production, so targeting them would prevent the bacteria from obtaining necessary energy. These enzymes are different from their eukaryotic counterparts, so the drugs targeting them should not affect the host. These enzymes are responsible for host cell recognition, so targeting them would prevent the host cell from being infected.Flag this QuestionQuestion 10arrow_forwardWhich of the following statements is false?a) A derivative of lactose serves as an inducer of the lac operon.b) Signal transduction provides a mechanism for a cell to sense the conditions of its external environment.c) Quorum sensing allows bacterial cells to sense the density of like cells.d) An example of a two-component regulatory system is the lactoseoperon, which is controlled by a repressor and an activator.e) An ORF is a stretch of DNA that may encode a protein.arrow_forwardIn the trp operon, if a mutation occurred in the gene for the repressor so that it could bind to the operator even in the absence of tryptophan____________. a) the inducer cannot bind trpO, so operon gene transcription occurs b) the active repressor cannot bind trpO, so operon gene transcription is attenuated c)the active repressor binds tpO, so operon gene transcription is always repressed d) the repressor binds the corepressor, and operon gene transcription occurs.arrow_forward
- Bacteriophage lambda is integrated in DNA of a host cell, which is exposed to UV light in a body of water in the environment. Describe the sequence of events that occurs in its life cycle. Briefly describe the role of the Lambda repressor (cI) and cII activator to regulate the switch between the lysogenic and lytic cycles of phage Lambda.arrow_forwardBriefly describe how the Nucleocapsid protein of rabies virus promotes the switch from transcription to viral genomic replication.arrow_forwardWhat evolutionary advantage would a retrovirus gain by having the ability to regulate the sites of splicing of its RNA?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
What Is A Virus ? ; Author: Peekaboo Kidz;https://www.youtube.com/watch?v=YS7vsBgWszI;License: Standard YouTube License, CC-BY