Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In response to increased temperature (a “heat shock"), heat shock proteins are activated by release from the NR/HSP complex. At the same time, transcription of HSP genes is activated. Why do you think the cell responds to a heat shock by increasing the activity of proteins that help refold misfolded proteins?

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Answer 1

Textbook Question

Chapter 37, Problem 1VCQ

Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In response to increased temperature (a “heat shock"), heat shock proteins are activated by release from the NR/HSP complex. At the same time, transcription of HSP genes is activated. Why do you think the cell responds to a heat shock by increasing the activity of proteins that help refold misfolded proteins?

Chapter 37, Problem 1VCQ, Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In

Expert Solution & Answer

Summary Introduction

To write:

The reasons behind the cell response to a heat shock to increase the activity of proteins that help refold misfolded proteins.

Introduction:

Heat shock proteins are the proteins, which act as the molecular chaperons. These are only produced in the cells when the cells undergo the stressed conditions. They play the functions in stabilizing the proteins and ensure the folding and refolding of the proteins.

Explanation of Solution

HSPs regulate the process of transcription. When the cell faced any stressed conditions, the intracellular nuclear receptor bond to these heat shock proteins and gets dissociated from the heat shock proteins upon hormone binding. This nuclear receptor and heat shock protein complexes activate the heat shock proteins and the process of transcription and translation take place.

After this, the hormone receptor complex binds a DNA sequence in the nucleus and form hormone response element. This element functions in initiating the process of gene transcription and translation and the resulting corresponding protein product will regulate the changes functions of cells. In case of high temperature, the structure of the protein gets unfold or get denature.

Conclusion

In case of high temperature, the proteins structure get unfold or get denature.

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Students have asked these similar questions

It is important for the cell to be able to terminate responses, and diminish responsiveness to prevent overstimulation. Cells have different mechanisms for this. One such mechanism is receptor down regulation. a.) Down regulation describes a decrease in the availability of hormones or neurotransmitters that bind to receptors on the surface of target cells, making the cells less likely to be stimulated. b.) Down regulation describes glycosylation of receptor proteins receptors on the surface of target cells in order to decrease the selectivity of ligand binding, making the cells less sensitive to a hormone or neurotransmitter. c.) Down regulation describes a decrease in the number of receptors on the surface of target cells, making the cells less sensitive to a hormone or neurotransmitter.

HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) MRNA transcripts can be collected from cells, made to glow with a fluorescent dye, and added to a microarray chip containing spots with DNA sequences from each of these genes. (In the depiction of the microarrays below o indicates no binding of the MRNA, and • indicates binding.) HDL-R PFK CD3 A Which of the gene expression patterns would you expect to see if you used mRNA from immune B cells to add to the microarray? O A O B O C O D

HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) Which of the following describes differences in the HDL-R gene in liver & immune cells? O The immune cell has permanently altered the HDL-R gene so that it can no longer be transcribed. O The immune cell has removed the estrogen response element from the HDL-R gene so that it cannot be transcribed. No difference O Only the liver cell retains the HDL-R gene, the immune cell has lost it.

Answer 2

Textbook Question

Chapter 37, Problem 1VCQ

Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In response to increased temperature (a “heat shock"), heat shock proteins are activated by release from the NR/HSP complex. At the same time, transcription of HSP genes is activated. Why do you think the cell responds to a heat shock by increasing the activity of proteins that help refold misfolded proteins?

Chapter 37, Problem 1VCQ, Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In

Expert Solution & Answer

Summary Introduction

To write:

The reasons behind the cell response to a heat shock to increase the activity of proteins that help refold misfolded proteins.

Introduction:

Heat shock proteins are the proteins, which act as the molecular chaperons. These are only produced in the cells when the cells undergo the stressed conditions. They play the functions in stabilizing the proteins and ensure the folding and refolding of the proteins.

Explanation of Solution

HSPs regulate the process of transcription. When the cell faced any stressed conditions, the intracellular nuclear receptor bond to these heat shock proteins and gets dissociated from the heat shock proteins upon hormone binding. This nuclear receptor and heat shock protein complexes activate the heat shock proteins and the process of transcription and translation take place.

After this, the hormone receptor complex binds a DNA sequence in the nucleus and form hormone response element. This element functions in initiating the process of gene transcription and translation and the resulting corresponding protein product will regulate the changes functions of cells. In case of high temperature, the structure of the protein gets unfold or get denature.

Conclusion

In case of high temperature, the proteins structure get unfold or get denature.

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Answer 3

Textbook Question

Chapter 37, Problem 1VCQ

Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In response to increased temperature (a “heat shock"), heat shock proteins are activated by release from the NR/HSP complex. At the same time, transcription of HSP genes is activated. Why do you think the cell responds to a heat shock by increasing the activity of proteins that help refold misfolded proteins?

Chapter 37, Problem 1VCQ, Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In

Expert Solution & Answer

Summary Introduction

To write:

The reasons behind the cell response to a heat shock to increase the activity of proteins that help refold misfolded proteins.

Introduction:

Heat shock proteins are the proteins, which act as the molecular chaperons. These are only produced in the cells when the cells undergo the stressed conditions. They play the functions in stabilizing the proteins and ensure the folding and refolding of the proteins.

Explanation of Solution

HSPs regulate the process of transcription. When the cell faced any stressed conditions, the intracellular nuclear receptor bond to these heat shock proteins and gets dissociated from the heat shock proteins upon hormone binding. This nuclear receptor and heat shock protein complexes activate the heat shock proteins and the process of transcription and translation take place.

After this, the hormone receptor complex binds a DNA sequence in the nucleus and form hormone response element. This element functions in initiating the process of gene transcription and translation and the resulting corresponding protein product will regulate the changes functions of cells. In case of high temperature, the structure of the protein gets unfold or get denature.

Conclusion

In case of high temperature, the proteins structure get unfold or get denature.

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Answer 4

Textbook Question

Chapter 37, Problem 1VCQ

Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In response to increased temperature (a “heat shock"), heat shock proteins are activated by release from the NR/HSP complex. At the same time, transcription of HSP genes is activated. Why do you think the cell responds to a heat shock by increasing the activity of proteins that help refold misfolded proteins?

Chapter 37, Problem 1VCQ, Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In

Expert Solution & Answer

Summary Introduction

To write:

The reasons behind the cell response to a heat shock to increase the activity of proteins that help refold misfolded proteins.

Introduction:

Heat shock proteins are the proteins, which act as the molecular chaperons. These are only produced in the cells when the cells undergo the stressed conditions. They play the functions in stabilizing the proteins and ensure the folding and refolding of the proteins.

Explanation of Solution

HSPs regulate the process of transcription. When the cell faced any stressed conditions, the intracellular nuclear receptor bond to these heat shock proteins and gets dissociated from the heat shock proteins upon hormone binding. This nuclear receptor and heat shock protein complexes activate the heat shock proteins and the process of transcription and translation take place.

After this, the hormone receptor complex binds a DNA sequence in the nucleus and form hormone response element. This element functions in initiating the process of gene transcription and translation and the resulting corresponding protein product will regulate the changes functions of cells. In case of high temperature, the structure of the protein gets unfold or get denature.

Conclusion

In case of high temperature, the proteins structure get unfold or get denature.

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Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

To write:

The reasons behind the cell response to a heat shock to increase the activity of proteins that help refold misfolded proteins.

Introduction:

Heat shock proteins are the proteins, which act as the molecular chaperons. These are only produced in the cells when the cells undergo the stressed conditions. They play the functions in stabilizing the proteins and ensure the folding and refolding of the proteins.

Explanation of Solution

HSPs regulate the process of transcription. When the cell faced any stressed conditions, the intracellular nuclear receptor bond to these heat shock proteins and gets dissociated from the heat shock proteins upon hormone binding. This nuclear receptor and heat shock protein complexes activate the heat shock proteins and the process of transcription and translation take place.

After this, the hormone receptor complex binds a DNA sequence in the nucleus and form hormone response element. This element functions in initiating the process of gene transcription and translation and the resulting corresponding protein product will regulate the changes functions of cells. In case of high temperature, the structure of the protein gets unfold or get denature.

Conclusion

In case of high temperature, the proteins structure get unfold or get denature.

Answer 8

Expert Solution & Answer

Summary Introduction

To write:

The reasons behind the cell response to a heat shock to increase the activity of proteins that help refold misfolded proteins.

Introduction:

Heat shock proteins are the proteins, which act as the molecular chaperons. These are only produced in the cells when the cells undergo the stressed conditions. They play the functions in stabilizing the proteins and ensure the folding and refolding of the proteins.

Explanation of Solution

HSPs regulate the process of transcription. When the cell faced any stressed conditions, the intracellular nuclear receptor bond to these heat shock proteins and gets dissociated from the heat shock proteins upon hormone binding. This nuclear receptor and heat shock protein complexes activate the heat shock proteins and the process of transcription and translation take place.

After this, the hormone receptor complex binds a DNA sequence in the nucleus and form hormone response element. This element functions in initiating the process of gene transcription and translation and the resulting corresponding protein product will regulate the changes functions of cells. In case of high temperature, the structure of the protein gets unfold or get denature.

Conclusion

In case of high temperature, the proteins structure get unfold or get denature.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

To write:

The reasons behind the cell response to a heat shock to increase the activity of proteins that help refold misfolded proteins.

Introduction:

Heat shock proteins are the proteins, which act as the molecular chaperons. These are only produced in the cells when the cells undergo the stressed conditions. They play the functions in stabilizing the proteins and ensure the folding and refolding of the proteins.

Answer 12

Explanation of Solution

HSPs regulate the process of transcription. When the cell faced any stressed conditions, the intracellular nuclear receptor bond to these heat shock proteins and gets dissociated from the heat shock proteins upon hormone binding. This nuclear receptor and heat shock protein complexes activate the heat shock proteins and the process of transcription and translation take place.

After this, the hormone receptor complex binds a DNA sequence in the nucleus and form hormone response element. This element functions in initiating the process of gene transcription and translation and the resulting corresponding protein product will regulate the changes functions of cells. In case of high temperature, the structure of the protein gets unfold or get denature.

Answer 13

Conclusion

In case of high temperature, the proteins structure get unfold or get denature.

Answer 14

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