Wild-type mice have brown fur and short tails. Loss of function of a particular geneproduces white fur, while loss of function of another gene produces long tails, and lossof function at a third locus produces agitated behavior. Each of these loss of functionalleles is recessive. If a wild-type mouse is crossed with a triple mutant, and their F1progeny is test-crossed, the following recombination frequencies are observed amongtheir progeny. Produce a genetic map for these loci.Brown, short tailed, normal: 955White, short tailed, normal:16Brown, short tailed, agitated: 0White, short tailed, agitated: 36Brown, long tailed, normal:White, long tailed, normal:Brown, long tailed, agitated:46014White, long tailed, agitated: 933

The recombination frequency is calculated as the number of recombinant progeny divided by the total…

Answered: Wild-type mice have brown fur and short…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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When Calvin Bridges observed a large number of offspring from a cross of white-eyed female Drosophila tored-eyed males, he found very rare white-eyed femalesand red-eyed males among the offspring. He was ableto show that these exceptions resulted from nondisjunction, such that the white-eyed females had received twoXs from the egg and a Y from the sperm, while thered-eyed males had received no sex chromosome fromthe egg and an X from the sperm. What progeny wouldhave arisen from these same kinds of nondisjunctionalevents if they had occurred in the male parent? Whatwould their eye colors have been?
In Drosophila, a heterozygous female for the X-linkedrecessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred inthe following phenotypic ratios.+ b c 460a + + 450a b c 32+ + + 38a + c 11+ b + 9 No other phenotypes were observed.(a) What progeny phenotypes are missing? Why?
A pure-breeding strain of squash that produced diskshaped fruits (see the accompanying illustration) wascrossed with a pure-breeding strain having long fruits.The F1 had disk fruits, but the F2 showed a new phenotype, sphere, and was composed of the followingproportions:Longlong 32 sphere 178 disk 270Sphere DiskPropose an explanation for these results, and showthe genotypes of the P, F1, and F2 generations.
In a vial of Drosophila, a research student noticedseveral female flies (but no male flies) with bag wingseach consisting of a large, liquid-filled blister insteadof the usual smooth wing blade. When bag-wingedfemales were crossed with wild-type males, 1/3 of theprogeny were bag-winged females, 1/3 were normalwinged females, and 1/3 were normal-winged males.Explain these results.
A wild-type fruit fly (heterozygous for gray body color andnormal wings) is mated with a black fly with vestigial wings.The offspring have the following phenotypic distribution: wildtype, 778; black vestigial, 785; black normal, 158; gray vestigial,162. What is the recombination frequency between these genesfor body color and wing size? Is this consistent with the resultsof the experiment in Figure 15.9?
Summer squash exist in long, spherical, or disk shapes. When atrue-breeding long-shaped strain was crossed to a true-breedingdisk-shaped strain, all of the F1 offspring were disk-shaped. Whenthe F1 offspring were allowed to self-fertilize, the F2 generationconsisted of a ratio of 9 disk-shaped to 6 round-shaped to 1 longshaped. Assuming the shape of summer squash is governed by twodifferent genes, with each gene existing in two alleles, propose amechanism to account for this 9:6:1 ratio
The mutant FMR-1 allele that causes fragile X syndrome is considered to be X-linked dominant withincomplete penetrance and variable expressivity.Why do most females heterozygous for one mutantand one normal allele have at least some symptomsof the disease?
F1 hybrids between two species of cotton, Gossypium barbadenseand Gossypium hirsutum, are very vigorous plants. However, F1crosses produce many seeds that do not germinate and a high percentageof very weak F2 offspring. Suggest two reasons for theseobservations.
In Drosophila, a heterozygous female for the X-linkedrecessive traits a, b, and c was crossed to a male that phenotypically expressed a, b, and c. The offspring occurred inthe following phenotypic ratios.+ b c 460a + + 450a b c 32+ + + 38a + c 11+ b + 9 No other phenotypes were observed.(a) What is the genotypic arrangement of the alleles ofthese genes on the X chromosome of the female?
In Drosophila, a cross was made between females expressing thethree X-linked recessive traits, scute bristles (sc), sable body (s),and vermilion eyes (v), and wild-type males. All females were wildtype in the F1, while all males expressed all three mutant traits.The cross was carried to the F2 generation and 1000 offspringwere counted, with the results shown in the following table. Nodetermination of sex was made in the F2 data. Question:Calculate the coefficient of coincidence; does this represent positive or negative interference? Phenotype Offspringsc s v 314+ + + 280+ s v 150sc + + 156sc + v 46+ s + 30sc s + 10+ + v 14
The A locus and the D locus are so tightly linked that norecombination is ever observed between them. If Ad/Ad is crossed with aD/aD and the F1 is intercrossed,what phenotypes will be seen in the F2 and in whatproportions?
You are studying tail length in a species of mice, where some mice have long tails and some have short tails.Preliminary results show that long tail is dominant, but you think the trait may be X-linked. Give the expectedoffspring phenotypic ratio for each cross if the trait is X- linked or if it is autosomal and answer the question atthe end. Make sure your phenotypic ratio is labeled with the complete phenotype (all relevant details). Cross #1: true-breeding long-tailed male x true-breeding short tailed female• Expectation if X-linked?• Expectation if autosomal?Cross #2: true-breeding long-tailed female x true-breeding short tailed male• Expectation if X-linked?• Expectation if autosomal?Compare the four results listed above. Briefly, why is a reciprocal cross is necessary to determine X (or Z)linkage?

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