Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 33.2, Problem 1TYK
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Describe the contribution of each of the following to the establishment and maintenance of membrane potential:
Part A
Na+K+ Pump
Passive movement of K+ across the membrane
Passive movement of Na+ across the membrane
Describe the contribution of each of the following to the establishment and maintenance of membrane potential:
Part A
Na+K+ Pump
Passive movement of K+ across the membrane
Passive movement of Na+ across the membrane
Part B
Resting membrane potential is approximately -70mV. Explain what resting membrane potential is and what -70mV refers to.
If a cell with the following ion concentrations had a resting membrane potential of -40mV which of the following can you conclude?
Extracellular: Cl- = 110 mM, Na+ = 145 mM, K+ = 5mM.
Intracellular Cl- = 20 mM, Na+ = 10 mM, K+ = 140mM
a) At rest it is only permeable to potassium
b) At rest it has some permeability to more than one of these ions
c) At rest it is only permeable to chloride
d) Rest it is not permeable to sodium
Chapter 33 Solutions
Principles of Biology
Ch. 33.1 - Which of the following is false? The CNS of...Ch. 33.1 - Prob. 2TYKCh. 33.1 - Prob. 1CCCh. 33.2 - Prob. 1CCCh. 33.2 - Prob. 1BCCh. 33.2 - Prob. 1TYKCh. 33.2 - The resting membrane potential occurs because the...Ch. 33.3 - Are ions the only substances that can move through...Ch. 33.3 - Prob. 1CCCh. 33.3 - Prob. 2CC
Ch. 33.3 - Which is false? Graded potentials may die out or...Ch. 33.3 - Action potentials require a threshold potential...Ch. 33.4 - Prob. 1CCCh. 33.4 - Prob. 1TYKCh. 33.4 - Prob. 2TYKCh. 33.5 - Prob. 1BCCh. 33.5 - Prob. 1TYKCh. 33.5 - Prob. 2TYKCh. 33.6 - Prob. 1CCCh. 33.6 - Prob. 2CCCh. 33.6 - Prob. 3CCCh. 33.6 - Prob. 1TYKCh. 33.6 - Prob. 2TYKCh. 33.7 - Prob. 1TYKCh. 33.7 - Therapeutic drugs that reduce symptoms of...Ch. 33 - Prob. 1TYCh. 33 - Prob. 2TYCh. 33 - Prob. 3TYCh. 33 - Neurons that function mainly in connecting other...Ch. 33 - Prob. 5TYCh. 33 - Prob. 6TYCh. 33 - Prob. 7TYCh. 33 - Prob. 8TYCh. 33 - Prob. 9TYCh. 33 - Prob. 10TYCh. 33 - Describe the differences between graded and action...Ch. 33 - Prob. 2CCQCh. 33 - Prob. 3CCQCh. 33 - Prob. 1CBQCh. 33 - Prob. 2CBQ
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- Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardWhat is the equilibrium membrane potential due to Na+ ions if the extracellular concentration of Na+ ions is 154 mM and the intracellular concentration of Na+ ions is 27 mM at 20 ∘C ? Please answer asap and in short and content should not be palgarised pleasearrow_forwardLet's say you have neurons in a petrie dish bath in a solution in which the extracellular K+ concentration is 5 mM and the intracellular concentration is 100 mM. Now you flood the dish with a solution containing K+ at 115 mM. What will be the Equilibrium Potential now for the cell (rounded up to the next integer)? O O mv O 4 mv O 70 mv O -70 mvarrow_forward
- A cell has an actual membrane potential (Em) at rest of -75mV. The equilibrium potential for Na+ is +120mV and the equilibrium potential for K+ is -95mV. Calculate the net driving force for Na+ in mV.arrow_forwardThe above depolarization of a neuron will result in which of the following ionic currents? a potassium current will transport K+ ions out of the cytoplasm a sodium current will transport Na+ ions out of the cytoplasm a potassium current will transport K+ ions into the cytoplasm a sodium current will transport K+ ions out of the cytoplasm E. a sodium current will transport Na+ ions into the cytoplasmarrow_forwardThere is no inward current at a membrane potential of +65mV because: The membrane potential is near or at the equilibrium potential for Na+ The membrane potential is near or at the equilibrium potential for neither Na+ or K+ The membrane potential is near or at the equilibrium potential for both Na+ and K+ The membrane potential is near or at the equilibrium potential for K+arrow_forward
- In an experiment, the extracellular [Na+] surrounding a nerve cell was reduced from 145 to 45 mM. Which of the following is the most likely effect of this on action potentials? No action potentials would occur because the concentration of extracellular Na+ is too low. The membrane potential would become more negative so the threshold for action potential generation could not be reached. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarisation phase would be slower. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarization phase would be more rapid.arrow_forwardIf the equilibrium potential for K* is -90mV, and the charge inside the cell is -70mV, which direction will K move across the membrane assuming there is permeability (membrane leak channels) which allow it to pass?arrow_forwardRepolarization occurs because Multiple Choice more sodium ions diffuse into the cell than potassium ions diffuse out of it. potassium ions continue to diffuse out of the cell after the inactivation gates of the voltage-gated sodium ion channels begin to close. the increased potassium ion permeability lasts slightly longer than the time required to bring the membrane potential back to its resting level. the extra efflux of potassium ions causes the membrane potential to become slightly more positive than the resting value. the inactivation gates of the voltage-gated sodium ion channels begin to open and the diffusion of sodium ions decreases.arrow_forward
- Membrane potential in cells is constantly fluctuating. These fluctuations are called graded potentials and we will learn more about them in future lectures. Look at the fluctuating graded potential in the graph as an example. If Cl- generally has a relatively low membrane permeability, how would increasing Cl- permeability affect this graph?arrow_forwardPlease explain what the resting membrane potential is and its value. Make sure you include all structures involved in the creation and maintenance of the resting membrane potential. Explanation addressing the question above Membrane potential is the difference in electric potential between the interior and the exterior of a biological cell. With respect to the exterior of the cell, typical values of membrane potential range from -40 mV to -80 mV. The membrane potential has two basic functions as a battery and transmitting signals between different parts of a cell. In non-excitable cells, the membrane potential is held at a relatively stable value, called the resting potential. The resting membrane potential of a neuron is about -70 mV. At rest, there are relatively more sodium ions outside the neuron and more potassium ions inside that neuron. It is determined by concentration gradients of ions across the membrane and by membrane permeability to each type of ion. Structure and…arrow_forwardThe membrane potential for an excitable cell membrane is -70 mV, for sodium ions the Nernst equilibrium potential is +50 mV, the conductivity of the single sodium channel is 10 pS. What is the electrochemical potential difference that is the driving force for sodium ions to migrate? How much current flows through an open sodium channel under these conditions?arrow_forward
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