Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 33.3, Problem 2TYK
Action potentials
- require a threshold potential around –55 to –50 mV in order to occur.
- have many different shapes and sizes, depending on how a cell was stimulated.
- occur only in myelinated neurons.
- occur whenever a neuron is sufficiently hyperpolarized.
- are limited in their frequency by inactivation gates of
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Based upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Help
A neuron has a resting membrane potential of -70 milivolts (mV) and a threshold value of -55 mV. Three synapses on the body of this neuron receive the
impulses listed below.
hyperpolarisation by 5 mV
• depolarisation by 15 mV
• depolarisation by 10 mV
ENTER THE MEMBRANE POTENTIAL AS A NUMBER WITH + OR - IN FRONT OF IT.
The final membrane potential will be
mV and this
cause an action potential becasue it is
v than the
Describe the contribution of each of the following to the establishment and maintenance of membrane potential:
Part A
Na+K+ Pump
Passive movement of K+ across the membrane
Passive movement of Na+ across the membrane
Part B
Resting membrane potential is approximately -70mV. Explain what resting membrane potential is and what -70mV refers to.
Chapter 33 Solutions
Principles of Biology
Ch. 33.1 - Which of the following is false? The CNS of...Ch. 33.1 - Prob. 2TYKCh. 33.1 - Prob. 1CCCh. 33.2 - Prob. 1CCCh. 33.2 - Prob. 1BCCh. 33.2 - Prob. 1TYKCh. 33.2 - The resting membrane potential occurs because the...Ch. 33.3 - Are ions the only substances that can move through...Ch. 33.3 - Prob. 1CCCh. 33.3 - Prob. 2CC
Ch. 33.3 - Which is false? Graded potentials may die out or...Ch. 33.3 - Action potentials require a threshold potential...Ch. 33.4 - Prob. 1CCCh. 33.4 - Prob. 1TYKCh. 33.4 - Prob. 2TYKCh. 33.5 - Prob. 1BCCh. 33.5 - Prob. 1TYKCh. 33.5 - Prob. 2TYKCh. 33.6 - Prob. 1CCCh. 33.6 - Prob. 2CCCh. 33.6 - Prob. 3CCCh. 33.6 - Prob. 1TYKCh. 33.6 - Prob. 2TYKCh. 33.7 - Prob. 1TYKCh. 33.7 - Therapeutic drugs that reduce symptoms of...Ch. 33 - Prob. 1TYCh. 33 - Prob. 2TYCh. 33 - Prob. 3TYCh. 33 - Neurons that function mainly in connecting other...Ch. 33 - Prob. 5TYCh. 33 - Prob. 6TYCh. 33 - Prob. 7TYCh. 33 - Prob. 8TYCh. 33 - Prob. 9TYCh. 33 - Prob. 10TYCh. 33 - Describe the differences between graded and action...Ch. 33 - Prob. 2CCQCh. 33 - Prob. 3CCQCh. 33 - Prob. 1CBQCh. 33 - Prob. 2CBQ
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- Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardWhich of the following voltages would most likely be measured during the relative refractory period? +30 mV 0 mV -45 mV -80 mvarrow_forwardAssume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and presynaptic excitatory neuron B terminates on the same postsynaptic cell on a dendrite located on the side of the cell body opposite the axon hillock. Explain why rapid firing of presynaptic neuron A could bring the postsynaptic neuron to threshold through temporal summation, thus initiating an action potential, whereas firing of presynaptic neuron B at the same frequency and the same magnitude of EPSPs may not bring the postsynaptic neuron to threshold.arrow_forward
- A neuron responds to adequate stimulation with _______, a type of self-propagating signal.arrow_forwardFigure 35.11 Potassium channel blockers, such as amiodarone and procainamide, which are used to treat abnormal electrical activity in the heart, called cardiac dysrhythmia, impede the movement of K+ through voltage-gated K+ channels. Which part of the action potential would you expect potassium channels to affect?arrow_forwardA common membrane-bound intermediary between the receptor and the effector protein within the plasma membrane is the __________________.arrow_forward
- Draw details of the repolarization phase of an action potential from the following descriptions of the sequences of AfterHyperPolarization (AHP) and AfterDePolarization (ADP) sequences. Make the distinct phases clear and noticeable (5 % each) A complex AHP consisting of a first component AHP, an ADP, and a second component AHP before repolarization to resting membrane potential a first fast AHP component, followed by a slower AHP, followed by a fast ADP, and a second late AHP component before repolarization to restarrow_forwardGive a detailed, step-by-step description of the stages of an action potential, including a description of and explanation for the refractory periods and the rising and falling phases as well as return to rest. In your explanation, make sure to include 1) summation principles, 2) key membrane potentials (values), 3) location of voltage changes along the membrane, 4) states of the various voltage-gated channels. The more detail, the better. There are 5 main steps.arrow_forwardIn an experiment, the extracellular [Na+] surrounding a nerve cell was reduced from 145 to 45 mM. Which of the following is the most likely effect of this on action potentials? No action potentials would occur because the concentration of extracellular Na+ is too low. The membrane potential would become more negative so the threshold for action potential generation could not be reached. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarisation phase would be slower. The nerve cell would still produce an action potential but its amplitude would be reduced and the depolarization phase would be more rapid.arrow_forward
- Consider the following three diagrams of a nerve cell membrane. They show resting potential, depolarization, and hyperpolarization. Figure out which one is which, then draw them in the order they occur in a cell that undergoes an action potential outside + Na* inside K* Na* Nat K Nat K Na potential: -80 mV outside + Na K* Na* inside Na+ K Nat Na* K+ potential: +30 mV outside Na Na Na Na* K+ inside K* Na* Kt potential: -70 mVarrow_forwardIn the figure to the left, name the 4 phases of the action potential (Note: you have to write in where phase 4 occurs). Describe what happens in each phase with a focus on Na+ and K+ flow through channels and the membrane potential. Discuss the importance of threshold. How does this relate to the concept of APs being all or none?arrow_forwardEach of the following is a correct relationship between action potential phase and channel status except Select one: O A. hyperpolarizing phase; Na channels open O B. repolarizing phase; K channels open O C. depolarization; Na channels open O D. hyperpolarizing phase; K channels open O E. repolarizing phase; Na channels closedarrow_forward
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