Concept explainers
Interpretation:
The mechanisms for the competing
Concept introduction:
The
The nucleophile forms a bond with the electrophilic carbon in the substrate, with the bond between that carbon and the leaving group breaking at the same time. Since the leaving group hasn’t departed when the nucleophile-carbon bond is formed, the nucleophile must approach the substrate from a direction opposite to the leaving group. This results in an inversion of configuration if the reaction center is a chiral carbon.
The
The E2 is a single-step, bimolecular elimination reaction. A proton from a carbon adjacent to the one attached to the leaving group is extracted by a base. The
An E1 reaction is a two-step, unimolecular reaction. The first step of E1 is the same as the first step of the
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Organic Chemistry: Principles and Mechanisms (Second Edition)
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