Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 43.1, Problem 2SB
Summary Introduction
To review:
The outline of molecular events that take place in the sliding filament model of muscle contraction.
Introduction:
Sliding filament model of muscle contraction is also called cross-bridge theory. It involves the actin and myosin proteins where the head of myosin filament attaches to actin filament forming the cross bridge. The contraction and relaxation of these muscles help in muscle contraction.
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Chapter 43 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 43.1 - Prob. 1SBCh. 43.1 - Prob. 2SBCh. 43.1 - Prob. 3SBCh. 43.2 - Prob. 1SBCh. 43.2 - Prob. 2SBCh. 43.3 - Prob. 1SBCh. 43.3 - Prob. 2SBCh. 43 - Prob. 1TYKCh. 43 - Prob. 2TYKCh. 43 - Prob. 3TYK
Ch. 43 - Prob. 4TYKCh. 43 - Prob. 5TYKCh. 43 - Prob. 6TYKCh. 43 - Which of the following is not an example of a...Ch. 43 - Endoskeletons: a. protect internal organs and...Ch. 43 - Prob. 9TYKCh. 43 - Prob. 10TYKCh. 43 - Prob. 11TYKCh. 43 - Prob. 12TYKCh. 43 - Prob. 13TYKCh. 43 - Prob. 14TYKCh. 43 - Prob. 15TYKCh. 43 - Prob. 1ITDCh. 43 - Prob. 2ITDCh. 43 - Prob. 3ITDCh. 43 - Prob. 4ITD
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- What is the function of the sarcoplasmic reticulum in muscle cell contraction?arrow_forwardThe sliding-filament model of skeletal-muscle contraction assumes a sliding or slipping of interdigitating filaments of actin and myosin. Electron micrographs show that during contraction the actin and my-osin filaments remain of constant length while the distance between Z lines shortens. Explain how this happens in terms of the molecular structure of the muscle filaments. What is the role of regulatory pro-teins (troponin and tropomyosin) in contraction?arrow_forwardExplain how the sliding filament model is responsible for muscle contraction.arrow_forward
- Thank youarrow_forwardExplain the molecular mechanism of muscle contraction.arrow_forwardDescribe the contraction of a muscle fiber, starting with what events take place at the neuromuscular junction, explaining how depolarization along the length of the sarcolemma occurs, the role of calcium (where it is released, what it binds to, etc.), and the events that occur after calcium binds to troponin. Draw a few simple, labelled diagrams of a neuromuscular junction and sarcomere and outline the steps of excitation-contraction coupling, including power stroke, recovery stroke, formation of cross bridges, role of ATP, etc.arrow_forward
- Pluripotent stem cells undergo a number of changes as they progress through developmental stages to become the terminally differentiated cell type known as a skeletal muscle myofiber. a) Describe the stages and key anatomic and functional changes that occur during differentiation of myofibers. b) Despite the fact that myofibers are terminally differentiated, muscle can regenerate itself following a trauma or injury. Describe how this can occur.arrow_forwardDiscuss the sequence of events between a Motor Neuron Action Potential and Skeletal Muscle Fiber Contraction?arrow_forwardCompare and contrast the major biochemical and mechanical properties of the three primary types of muscle fibers found in human skeletal muscle.arrow_forward
- Explain Molecular Mechanisms of Skeletal Muscle Contraction?arrow_forwardAs mentioned in class, one additional major use of ATP in skeletal muscle (besides powering the myosin heads) is the recycling of calcium ions back into the sarcoplasmic reticulum after depolarization. The resting concentration of Ca++ in the muscle cell cytoplasm is about 50-100 nM, and the spike concentration after depolarization is about 10-20 μΜ. a) Consider a single sarcomere. What is the number of free calcium ions within the sarcomere at rest? What is the number of free calcium ions after depolarization? b) The major ion pump responsible for calcium ion recycling is SERCA (sarco/endoplasmic reticulum calcium ATPase). SERCA uses one molecule of ATP to pump two calcium ions, and the resting level can be restored in about 10-20 ms. How many molecules of ATP are used in a single sarcomere for pumping calcium in a single "twitch"? c) Assume that a single "twitch" is sufficient to drive one sarcomere from its fully extended length (about 2.5 µm) to its fully contracted length (about 1…arrow_forwardWhat evidence supports a sliding filament-crossbridge mechanism of contraction in smooth muscle?arrow_forward
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