Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 16.3, Problem 2TYK
Which of the following statements regarding X-chromosome inactivation is false?
- Xic is the site where X-chromosome inactivation begins.
- Xic is where the Xist gene is located.
- The Xist gene on the inactivated X chromosome (the Barr body) is not expressed.
- The product of the Xist gene coats the inactivated X chromosome.
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Which of the following statements regarding X-inactivation is TRUE?(posted)
Inactivated X chromosomes are only found in somatic cells of females.
After X-inactivation happens in a cell, all daughter cells resulting from mitotic events of that cell will have the same X chromosome ina none of the statements listed here are true
X-inactivation is a random event that happens during human development right before a fetus is born. all of the statements listed here are true)
Following X-chromosome inactivation, most of the genes on theinactivated X chromosome are silenced. Explain how. Name onegene that is not silenced.
What is the spreading phase of X-chromosome inactivation? Whydo you think it is called a spreading phase?
Chapter 16 Solutions
Principles of Biology
Ch. 16.1 - Which of the following is an epigenetic change...Ch. 16.2 - If you crossed an Igf 2 Igf 2- male mouse to an...Ch. 16.2 - Prob. 1TYKCh. 16.2 - Prob. 2TYKCh. 16.3 - Prob. 1CCCh. 16.3 - Prob. 1TYKCh. 16.3 - Which of the following statements regarding...Ch. 16.4 - Prob. 1TYKCh. 16.4 - Prob. 2TYKCh. 16.5 - Prob. 1BC
Ch. 16.5 - Prob. 1CCCh. 16.5 - Prob. 1TYKCh. 16.5 - Prob. 2TYKCh. 16.6 - Prob. 1CCCh. 16.6 - Prob. 1BCCh. 16.6 - Prob. 1TYKCh. 16.6 - Genes that are linked do not conform to Mendels...Ch. 16 - Which of the following is an example of an...Ch. 16 - In mice, the allele of the Igf2 gene that is...Ch. 16 - Prob. 3TYCh. 16 - The marking process for genomic imprinting...Ch. 16 - According to Mary Lyons hypothesis, the patchwork...Ch. 16 - Prob. 6TYCh. 16 - Prob. 7TYCh. 16 - Prob. 8TYCh. 16 - Prob. 9TYCh. 16 - Prob. 10TYCh. 16 - Prob. 1CCQCh. 16 - Prob. 2CCQCh. 16 - Prob. 3CCQCh. 16 - Prob. 1CBQCh. 16 - Prob. 2CBQ
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Although most tortoiseshell cats are female, a litter of kittens will occasionally contain a male tortoiseshell. Which of the following can explain tortoiseshell coat color in a male kitten? Please explain in detail. The male kitten has an extra Y chromosome The male kitten has an extra X chromosome The male kitten has no X chromosome The male kitten cannot carry out X-inactivationarrow_forwardOutline the process of X-chromosome inactivation.arrow_forwardwhat is X-chromosome reactivation.?arrow_forward
- Why do females not produce more protein encoded by genes on the X chromosome than males? One X chromosome is inactivated There are no proteins encoded by genes on the X chromosome They do produce more protein encoded by genes on the X chromosome The genes on the Y chromosome are the same as the ones on the X chromosomearrow_forwardWhich of the following statements is false? Dosage compensation is accomplished in humans by stimulation of gene expression from the single X chromosome. Dosage compensation is accomplished in humans by inactivating a female X chomosome. An individual with Turner Syndrome has no Barr bodies. An individual with Klinefelter syndrome generally has one Barr body. A typical XX human female has one Barr body.arrow_forwardBarr bodies are formed to adjust X chromosome dosage in species other than humans, such as Drosophila (fruit flies) and C. elegans (nematodes). True or False ?arrow_forward
- In the past, the IOC has employed two genetic sex- determination tests. The Barr body test screens for the presence of two X chromosomes. In XX somatic cells, one copy of the X chromosome condenses into a largely inactive structure called a Barr body, which can be seen using a light microscope. In more recent years, a polymerase chain reaction-based screen has been used to amplify the DNA sequence of the SRY gene, which is found only on the Y chromosome. Based on their karyotypes, what would be the outcome of these two tests for each of the four individuals? Drag the labels to indicate the presence or absence of a Barr body and the SRY gene sequence.arrow_forwardThe Xg cell-surface antigen is coded for by a gene located on the X chromosome. No equivalent gene exists on the Y chromosome. Two codominant alleles of this gene have been identified: Xg1 and Xg2. A woman of genotype Xg2/Xg2 bears children with a man of genotype Xg1/Y, and they produce a son with Klinefelter syndrome of genotype Xg1/Xg2Y. Using proper genetic terminology, briefly explain how this individual was generated. In which parent and in which meiotic division did the mistake occur?arrow_forwarddescribe X-chromosome reactivation.arrow_forward
- Occasionally, a mouse X chromosome is broken into two pieces and each piece becomes attached to a different autosome. In this event, the genes on only one of the two pieces undergo X inactivation. What does this observation indicate about the mechanism of X-chromosome inactivation?arrow_forwardThe genotype of a dwarf mouse is Igf2 Igf2–. What is the genotype of its father who has normal body size? Indicate which allele is on the maternal chromosome and which allele is on the paternal chromosome for both dwarf mouse and its father.arrow_forwardFigure 19.25 shows that the Sxl protein binds to the mRNA of the msl-2 gene, inhibiting translation of the mRNA’s proper reading frame. The MSL-2 protein is a transcription factor that binds to the X chromosome in XY males to double the level of X-linked gene transcription, thus equalizing X-linked gene expression in XY males and XX females. a. In which sex, XY males or XX females, would the Sxl protein bind to the msl-2 mRNA? b. As discussed in Problem 35, some Sxl alleles are lethal to females and others are lethal to males. Is the function of Sxl in regulating the synthesis of Msl-2 protein sufficient to explain the sex-specific lethality caused by both kinds of alleles? c. Predict the effect of loss-of-function mutations in msl-2 on male and female fertility and viability.arrow_forward
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