Concept explainers
(a)
Interpretation:
The most basic site in the given species is to be determined.
Concept introduction:
Basicity of a compound depends on the
pKa value of a functional group in different compounds is similar in the absence of resonance involving the functional group.
This concept can be used to compare the basicity of different functional groups that may be present in a compound.
(b)
Interpretation:
The most basic site in the given species is to be determined.
Concept introduction:
Basicity of a compound depends on the functional groups present in it. The pKa value of a functional group determines its acidic strength as well as the strength of its conjugate base. The conjugate base formed from a weak acid is strong, and the conjugate base formed from a strong acid is a weak. The higher the pKa, weaker the acid and therefore stronger the conjugate base.
pKa value of a functional group in different compounds is similar in the absence of resonance involving the functional group.
This concept can be used to compare the basicity of different functional groups that may be present in a compound.
(c)
Interpretation:
The most basic site in the given species is to be determined.
Concept introduction:
Basicity of a compound depends on the functional groups present in it. The pKa value of a functional group determines its acidic strength as well as the strength of its conjugate base. The conjugate base formed from a weak acid is strong, and the conjugate base formed from a strong acid is a weak. The higher the pKa, weaker the acid and therefore stronger the conjugate base.
pKa value of a functional group in different compounds is similar in the absence of resonance involving the functional group.
This concept can be used to compare the basicity of different functional groups that may be present in a compound.
(d)
Interpretation:
The most basic site in the given species is to be determined.
Concept introduction:
Basicity of a compound depends on the functional groups present in it. The pKa value of a functional group determines its acidic strength as well as the strength of its conjugate base. The conjugate base formed from a weak acid is strong, and the conjugate base formed from a strong acid is a weak. The higher the pKa, weaker the acid and therefore stronger the conjugate base.
pKa value of a functional group in different compounds is similar in the absence of resonance involving the functional group.
This concept can be used to compare the basicity of different functional groups that may be present in a compound.
(e)
Interpretation:
The most basic site in the given species is to be determined.
Concept introduction:
Basicity of a compound depends on the functional groups present in it. The pKa value of a functional group determines its acidic strength as well as the strength of its conjugate base. The conjugate base formed from a weak acid is strong, and the conjugate base formed from a strong acid is a weak. The higher the pKa, weaker the acid and therefore stronger the conjugate base.
pKa value of a functional group in different compounds is similar in the absence of resonance involving the functional group.
This concept can be used to compare the basicity of different functional groups that may be present in a compound.
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Chapter 6 Solutions
Organic Chemistry: Principles and Mechanisms (Second Edition)
- Please draw the conjugate base for each below as indicated in the picture below and offer a detailed explanation. Thank you so much.arrow_forwardHighlight in red each acidic location on the organic molecule at left. Highlight in blue each basic location on the organic molecule at right.arrow_forwardOn the following two molecules, circle the most acidic proton, andrationalize your choice. Simply citing pKa values is not sufficient to answer this question. Include structures and a brief written explanation to support your choice.arrow_forward
- 2) For two of the following pairs of compounds, identify the most basic atom in each compound, and determine which of each pair is more basic, explaining your reasoning. a) b)arrow_forwardThe structure shown below is has a very high pKa because the conjugate base is very unstable. Using the provided resonance structures, draw the curved electron-pushing arrows to show the deprotonation step. Then, draw the curved electron-pushing arrows to show the interconversion between resonance hybrid contributors. Be sure to account for all bond-breaking and bond-making steps. H Select to Add Arrows CH3CH2CH2CH2Li H Select to Edit Arrows H H LIⒸarrow_forwardfor each pair of compounds, circle the the most acidic proton in each molecule, and then indicate which is the stronger acid of the twoarrow_forward
- In the picture, Each of the following compounds has more than one kind of (a-H's). First draw all a-H in, and circle the ones that are more acidic (that is, the ones more likely removed with a suitable base) in each compound. Thank you!arrow_forwardProvide the approximate pKa of the following and circle the most acidic hydrogen.arrow_forwardCircle the most acidic compound of each of the following pairsarrow_forward
- Consider the below molecule and its hydrogen atoms labeled a through e. Rank the named hydrogen atoms in order of increasing acidity. Explain your choice.arrow_forwardShow the mechanism for the forward acid-base reactions only. In other words, use arrow formalism to track electrons. Acid-base mechanismstypicallyrequire two arrows, flowing in the same direction.Refer to your notesfor proper arrow direction and flow, if necessary. It should be obvious which is the acid and which is the base.arrow_forwardIn each pair circle the most basic, assuming that the solvent is waterarrow_forward
Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning