Explanation Primates and birds do not possess the enzyme, urate oxidase. This enzyme is responsible for the conversion of uric acid to allantoin. This melatonin is then converted to allonate and is finally to urea. The absence of this enzyme can result in the condition of gout, as the conversion of uric acid to allonate is not catalyzed...

Biochemistry: The Molecular Basis of Life

6th Edition

ISBN: 9780190209896

Author: Trudy McKee, James R. McKee

Publisher: Oxford University Press

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Question

Chapter 15, Problem 5Q

Summary Introduction

To explain:

The reason accounting for the nonoccurrence of gout in the animals possessing urate oxidase.

Introduction:

Gout is a medical condition characterized by an increase in uric acid. Uric acid crystallizes and deposits in the joints. The common symptoms of the mentioned medical condition include pain, rednes, snd swelling in the joints. It is an inflammatory form of arthritis where the episodes of pain are sudden and severe.

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Chapter 15 Solutions

Biochemistry: The Molecular Basis of Life

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Solution Summary: The author explains that primates and birds do not possess the enzyme, urate oxidase, which is responsible for the conversion of uric acid to allantoin.

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