Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 15, Problem 63TQ
Summary Introduction

To review:

The enzymes that catalyze the formation and regeneration of 5,6,7,8-tetrahydrobiopterinand cause the symptoms of phenylketonuria (PKU).

Introduction:

5,6,7,8-tetrahydrobiopterin (BH4) is a pteridine with a unique ring structure. It follows the pyrimidine ring structure. It is named so as it was first isolated from the wings (Ptera in Greek means wings) of the English butterfly. It is a cofactor that is involved in many enzyme activities and is present in almost all the tissues of higher animals. 

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Biochemistry: The Molecular Basis of Life

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