Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 15, Problem 74TQ
Summary Introduction
To review:
The Krebs bicycle and calculate the ATPs degraded or synthesized and if the urea cycle is theenergy-requiring or synthesizing reaction.
Introduction:
The relationship between the CAC (citric acid cycle) and the urea cycle is often referred to as the Krebs bicycle. The urea cycle is a process of several biochemical reactions that occur in ureotelic animals for the conversion of toxic ammonia to nontoxic urea. This was the first
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_____________ pathways can function in both anabolic and catabolic processes.
A metabolic pathway that functions in both anabolic andcatabolic processes is called an _____________________pathway.
The Hatch–Slack pathway is an alternative name for _____________.
Chapter 15 Solutions
Biochemistry: The Molecular Basis of Life
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- In the glyoxylate cycle, two molecules of acetyl-CoA areconverted into _______________ and malate.arrow_forwardOrotic aciduria is an autosomal recessive disease caused by a deficiency of the enzyme UMP synthase (a bifunctional protein composed of orotate pyrophosphoribosyl transferase and OMP decarboxylase activities). What symptom accounts for the disease’s name? Suggest a possible treatment.arrow_forwardAmino acids that degrade yielding acetyl-CoA or acetoacetyl-CoA are referred to as _____________.arrow_forward
- Orotic aciduria results when one of the enzyme activities of UMP synthetase is absent. This syndrome is characterized by large amounts of orotic acid in the blood and urine, megaloblastic anemia (characterized by large, immature , and dysfunctional red blood cells) and retarded growth. Suggest a possible treatment for this condition.arrow_forwardThe hexokinases are a class of enzymes that catalyze the ATP-dependent phosphorylation of hexoses (sugars with six carbons). The hexokinases will bind only D-hexose sugars and not their L-counterparts. In general terms, describe the features of enzyme structure that make this specificity possible.arrow_forwardThe uncatalyzed reaction rate for the conversion of substrate X to product Y is one year. The enzyme-catalyzedrate is one millisecond. Describe the features of theenzyme that are probably responsible for this ratedifference.arrow_forward
- _____________ is a small matrix protein that functions as an electron acceptor for dehydrogenases in fatty acid oxidation.arrow_forward_____________ produced in the citric acid cycle is an important carbon source for gluconeogenesis.arrow_forwardQuestion 9 The nucleoside monophosphates are seen in metabolic pathways because their phosphoric anhydride bonds can be hydrolyzed off for energy. A) True B) Falsearrow_forward
- The acetyl group of acetyl-CoA is derived from the breakdown of lipids, carbohydrates, and certain _____________.arrow_forwardQuestion 1. a) Explain how 5 specific fatty acids ultimately generate specific classes of prostaglandins and leukotrienes that are involved in blood pressure, platelet aggregation and inflammation.b) Indicate and explain the specific effects of each of these classes of prostaglandins and leukotrienes on blood pressure, platelet aggregation and inflammation.c) Identify which foods, functional foods and nutraceuticals provide one or more of these 5 fatty acids.arrow_forwardGlycogen phosphorylase, an enzyme that catalyzes the breakdown of glycogen to form glucose, is active when a phosphate group is added. This is an example of enzyme regulation by ____________________________.arrow_forward
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